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Fourier Transform Infrared microspectroscopy identifies single cancer cells in blood. A feasibility study towards liquid biopsy (2023)
Journal Article
Dowling, L. M., Roach, P., Magnussen, E. A., Kohler, A., Pillai, S., van Pittius, D. G., …Sulé-Suso, J. (in press). Fourier Transform Infrared microspectroscopy identifies single cancer cells in blood. A feasibility study towards liquid biopsy. PLoS ONE, 18(8), Article e0289824. https://doi.org/10.1371/journal.pone.0289824

The management of cancer patients has markedly improved with the advent of personalised medicine where treatments are given based on tumour antigen expression amongst other. Within this remit, liquid biopsies will no doubt improve this personalised c... Read More about Fourier Transform Infrared microspectroscopy identifies single cancer cells in blood. A feasibility study towards liquid biopsy.

Fourier transform infrared spectroscopy as a non-destructive method for analysing herbarium specimens. (2023)
Journal Article
Barnes, M., Sule-Suso, J., Millett, J., & Roach, P. (2023). Fourier transform infrared spectroscopy as a non-destructive method for analysing herbarium specimens. Biology Letters, 19(3), Article 20220546. https://doi.org/10.1098/rsbl.2022.0546

Dried plant specimens stored in herbaria are an untapped treasure chest of information on environmental conditions, plant evolution and change over many hundreds of years. Owing to their delicate nature and irreplaceability, there is limited access f... Read More about Fourier transform infrared spectroscopy as a non-destructive method for analysing herbarium specimens..

Domes and semi-capsules as model systems for infrared microspectroscopy of biological cells. (2023)
Journal Article
Solheim, J., Brandsrud, M., Kong, B., Banyasz, A., Borondics, F., Micouin, G., …Kohler, A. (2023). Domes and semi-capsules as model systems for infrared microspectroscopy of biological cells. Scientific reports, 13(1), Article 3165. https://doi.org/10.1038/s41598-023-30130-z

It is well known that infrared microscopy of micrometer sized samples suffers from strong scattering distortions, attributed to Mie scattering. The state-of-the-art preprocessing technique for modelling and removing Mie scattering features from infra... Read More about Domes and semi-capsules as model systems for infrared microspectroscopy of biological cells..