Outputs (143)

Inadequacy of Existing Clinical Prediction Models for Predicting Mortality after Transcatheter Aortic Valve Implantation (2016)
Journal Article
Mamas. (2016). Inadequacy of Existing Clinical Prediction Models for Predicting Mortality after Transcatheter Aortic Valve Implantation. American Heart Journal, 97-105. https://doi.org/10.1016/j.ahj.2016.10.020

Background
The performance of emerging transcatheter aortic valve implantation (TAVI) clinical prediction models (CPMs) in national TAVI cohorts distinct from those where they have been derived is unknown. This study aimed to investigate the perform... Read More about Inadequacy of Existing Clinical Prediction Models for Predicting Mortality after Transcatheter Aortic Valve Implantation.

Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system (2016)
Journal Article
Mamas, M., & Mallen, C. (2016). Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system. Medicine, e4973. https://doi.org/10.1097/md.0000000000004973

Multimorbidity is common among older people and presents a major challenge to health systems worldwide. Metrics of multimorbidity are, however, crude: focusing on measuring comorbid conditions at single time-points rather than reflecting the longitud... Read More about Predicting Mortality from Change-over-time in the Charlson Comorbidity Index: A retrospective cohort study in a data-intensive UK health system.

Comparison of the Effects of Incomplete Revascularization on 12-month Mortality in Patients <80 compared to =80 Years of Age Undergoing Percutaneous Coronary Intervention (2016)
Journal Article
Mamas. (2016). Comparison of the Effects of Incomplete Revascularization on 12-month Mortality in Patients

Although randomized trial data suggest that complete revascularization improves outcomes after percutaneous coronary intervention (PCI), the impact of differing revascularization strategies in octogenarians is not well defined. We performed a retrosp... Read More about Comparison of the Effects of Incomplete Revascularization on 12-month Mortality in Patients <80 compared to =80 Years of Age Undergoing Percutaneous Coronary Intervention.

Rheumatic mitral valve disease is associated with worse outcomes in stroke: a Thailand National Database Study (2016)
Journal Article
Mamas. (2016). Rheumatic mitral valve disease is associated with worse outcomes in stroke: a Thailand National Database Study. Stroke, 2695-2701. https://doi.org/10.1161/STROKEAHA.116.014512

Background and Purpose—
Rheumatic valvular heart disease is associated with the increased risk of cerebrovascular events, although there are limited data on the prognosis of patients with rheumatic mitral valve disease (RMVD) after stroke.

Method... Read More about Rheumatic mitral valve disease is associated with worse outcomes in stroke: a Thailand National Database Study.

The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice (2016)
Journal Article
Mamas. (2016). The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice. Biochemical and Biophysical Research Communications, 708-714. https://doi.org/10.1016/j.bbrc.2016.09.147

The G-protein-coupled receptors (GPCRs) family of proteins play essential roles in the heart, including in the regulation of cardiac hypertrophy. One member of this family, the oxoglutarate receptor 1 (OXGR1), may have a crucial role in the heart bec... Read More about The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice.

Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis (2016)
Journal Article
Wu, P., Shing Kwok, C., Haththotuwa, R., Kotronias, R. A., Babu, A., Fryer, A. A., …Mamas, M. A. (2016). Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis. Diabetologia, 59, 2518-2526. https://doi.org/10.1007/s00125-016-4098-x

Aims/hypothesis: Pre-eclampsia is a pregnancy-specific multi-system disorder and a state of physiological insulin resistance. Our aim is to systematically evaluate and quantify the evidence on the relationship between pre-eclampsia and the future ris... Read More about Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis.

Influence of access site choice for cardiac catheterization on risk of adverse neurological events: a systematic review and meta-analysis (2016)
Journal Article
Mamas, & Nolan. (2016). Influence of access site choice for cardiac catheterization on risk of adverse neurological events: a systematic review and meta-analysis. American Heart Journal, 107-119. https://doi.org/10.1016/j.ahj.2016.06.027

Background: Stroke is a rare but potentially catastrophic complication of cardiac catheterization. While some procedural aspects are known to influence stroke risk, the impact of radial versus femoral access site use is unclear. Early observational s... Read More about Influence of access site choice for cardiac catheterization on risk of adverse neurological events: a systematic review and meta-analysis.

Impact of hemoglobin levels and anemia on mortality in acute stroke: analysis of UK regional registry data, systematic review and meta-analysis (2016)
Journal Article
Mamas. (2016). Impact of hemoglobin levels and anemia on mortality in acute stroke: analysis of UK regional registry data, systematic review and meta-analysis. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.115.003019

Background: The impact of hemoglobin levels and anemia on stroke mortality remains controversial. We aimed to systematically assess this association and quantify the evidence. Methods and Results: We analysed data from a cohort of 8,013 stroke patien... Read More about Impact of hemoglobin levels and anemia on mortality in acute stroke: analysis of UK regional registry data, systematic review and meta-analysis.

The incidence, determinants and outcomes of coronary perforation during percutaneous coronary intervention in the United Kingdom between 2006–2013: an analysis of 527,121 cases from the British Cardiovascular Intervention Society database (2016)
Journal Article
Mamas. (2016). The incidence, determinants and outcomes of coronary perforation during percutaneous coronary intervention in the United Kingdom between 2006–2013: an analysis of 527,121 cases from the British Cardiovascular Intervention Society database. Circulation: Cardiovascular Interventions, https://doi.org/10.1161/CIRCINTERVENTIONS.115.003449

Background: As coronary perforation (CP) is a rare but serious complication of percutaneous coronary intervention (PCI) the current evidence base is limited to small series. Using a national PCI database the incidence, predictors and outcomes of CP a... Read More about The incidence, determinants and outcomes of coronary perforation during percutaneous coronary intervention in the United Kingdom between 2006–2013: an analysis of 527,121 cases from the British Cardiovascular Intervention Society database.

Meta-analysis of Percutaneous Coronary Intervention with Drug Eluting Stent Versus Coronary Artery Bypass Grafting for Isolated Proximal Left Anterior Descending Coronary Disease (2016)
Journal Article
Mamas. (2016). Meta-analysis of Percutaneous Coronary Intervention with Drug Eluting Stent Versus Coronary Artery Bypass Grafting for Isolated Proximal Left Anterior Descending Coronary Disease. American Journal of Cardiology, 1171-1177. https://doi.org/10.1016/j.amjcard.2016.07.030

We performed a meta-analysis of the studies comparing the efficacy and safety of coronary artery bypass surgery (CABG) against percutaneous coronary intervention with drug-eluting stents (PCI-DES) among patients with isolated LAD disease. Due to limi... Read More about Meta-analysis of Percutaneous Coronary Intervention with Drug Eluting Stent Versus Coronary Artery Bypass Grafting for Isolated Proximal Left Anterior Descending Coronary Disease.