Outputs (57)

The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells (2016)
Journal Article
Mohammed, H. N., Pickard, M. R., & Mourtada-Maarabouni, M. (2016). The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells. Cellular Signalling, 1389 - 1400. https://doi.org/10.1016/j.cellsig.2016.06.011

Background:
The control of breast cell survival is of critical importance for preventing breast cancer initiation and progression. The activity of many proteins which regulate cell survival is controlled by reversible phosphorylation, so that the re... Read More about The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells.

The Vacuolar ATPase Subunit E regulates cell death in human breast cancer cells (2015)
Presentation / Conference
Maarabouni, M. (2015, November). The Vacuolar ATPase Subunit E regulates cell death in human breast cancer cells. Presented at 11th NCRI Cancer Conference, Liverpool

The long non-coding RNA NEAT1 regulates cell survival in breast cancer cell lines (2015)
Presentation / Conference
Almnaseer, Z., Pickard, M. R., & Mourtada Maarabouni, M. (2015, November). The long non-coding RNA NEAT1 regulates cell survival in breast cancer cell lines. Presented at 11th NCRI Cancer Conference, Liverpool

Role of Protein Phosphatase 4 in Chronic Myeloid Leukaemia (2015)
Presentation / Conference
Al-Khazraji, S., & Mourtada Maarabouni, M. (2015, November). Role of Protein Phosphatase 4 in Chronic Myeloid Leukaemia. Presented at 11th NCRI Cancer Conference, Liverpool

The vacuolar ATPase subunit E controls apoptosis and is down-regulated in breast cancer (2015)
Presentation / Conference
Mohammed, S., & Mourtada-Maarabouni, M. (2015, November). The vacuolar ATPase subunit E controls apoptosis and is down-regulated in breast cancer. Poster presented at 11th NCRI Cancer Conference, Liverpool

Background
Vacuolar H+-ATPase (v-ATPase) is a large multisubunit proton pump that mediates the acidification of many intracellular compartments. Previous studies have strongly implicated v-ATPase in carcinogenesis and tumour progression and indicat... Read More about The vacuolar ATPase subunit E controls apoptosis and is down-regulated in breast cancer.

Interactions between PP4 and PEA-15 in the regulation of cell proliferation and apoptosis of breast cancer cells (2015)
Presentation / Conference
Mohammed, H., Pickard, M., & Mourtada-Maarabouni, M. (2015, November). Interactions between PP4 and PEA-15 in the regulation of cell proliferation and apoptosis of breast cancer cells. Presented at 11th NCRI Cancer Conference, Liverpool

Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate (2014)
Journal Article
Hudson, W. H., Pickard, M. R., de Vera, I. M. S., Kuiper, E. G., Mourtada-Maarabouni, M., Conn, G. L., …Ortlund, E. A. (2014). Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate. Nature Communications, 5(1), Article 5395. https://doi.org/10.1038/ncomms6395

The majority of the eukaryotic genome is transcribed, generating a significant number of long intergenic noncoding RNAs (lincRNAs). Although lincRNAs represent the most poorly understood product of transcription, recent work has shown lincRNAs fulfil... Read More about Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate.

Regulation of the cell cycle and cell death by protein phosphatase 4 in breast cancer cell lines (2014)
Presentation / Conference
Mohammed, H., Pickard, M., Williams, G., & Mourtada-Maarabouni, M. (2014, November). Regulation of the cell cycle and cell death by protein phosphatase 4 in breast cancer cell lines. Presented at NCRI Cancer Conference, Liverpool

Role of GAS5 Noncoding RNA in Mediating the Effects of Rapamycin and Its Analogues on Mantle Cell Lymphoma Cells (2014)
Journal Article
Mourtada-Maarabouni, M., & Williams, G. T. (2014). Role of GAS5 Noncoding RNA in Mediating the Effects of Rapamycin and Its Analogues on Mantle Cell Lymphoma Cells. Clinical Lymphoma, Myeloma and Leukemia, 14(6), 468-473. https://doi.org/10.1016/j.clml.2014.02.011

Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS5 (2013)
Journal Article
Mourtada-Maarabouni, M., & Williams, G. T. (2013). Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS5. BioMed Research International, 2013, Article 358015. https://doi.org/10.1155/2013/358015

Nonsense-mediated decay is a key RNA surveillance mechanism responsible for the rapid degradation of mRNAs containing premature termination codons and hence prevents the synthesis of truncated proteins. More recently, it has been shown that nonsense-... Read More about Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS5.