Outputs (1141)

Accessing active fragments for drug discovery utilising nitroreductase biocatalysis. (2024)
Journal Article
Holder, L., Yuce, E., Oriomah, G., Jenkins, A.-P., Reynisson, J., Winter, A., & Cosgrove, S. (in press). Accessing active fragments for drug discovery utilising nitroreductase biocatalysis. ChemBioChem, 25(18), Article e202400428. https://doi.org/10.1002/cbic.202400428

Biocatalysis has played a limited role in the early stages of drug discovery. This is often attributed to the limited substrate scope of enzymes not affording access to vast areas of novel chemical space. Here, we have shown a promiscuous nitroreduct... Read More about Accessing active fragments for drug discovery utilising nitroreductase biocatalysis..

Entomological survey of sibling species in the Anopheles funestus group in Tanzania confirms the role of Anopheles parensis as a secondary malaria vector. (2024)
Journal Article
Mapua, S. A., Samb, B., Nambunga, I. H., Mkandawile, G., Bwanaly, H., Kaindoa, E. W., …Tripet, F. (2024). Entomological survey of sibling species in the Anopheles funestus group in Tanzania confirms the role of Anopheles parensis as a secondary malaria vector. Parasites and Vectors, 17(1), 1-10. https://doi.org/10.1186/s13071-024-06348-9

Malaria transmission in Tanzania is driven by mosquitoes of the Anopheles gambiae complex and Anopheles funestus group. The latter includes An. funestus s.s., an anthropophilic vector, which is now strongly resistant to public health insecticides, an... Read More about Entomological survey of sibling species in the Anopheles funestus group in Tanzania confirms the role of Anopheles parensis as a secondary malaria vector..

International Biological Flora: Ceratonia siliqua (2024)
Journal Article
Thomas, P. A., Garcia‐Martí, X., Mukassabi, T. A., & Tous, J. (in press). International Biological Flora: Ceratonia siliqua. Journal of Ecology, https://doi.org/10.1111/1365-2745.14325

This account presents information on all aspects of the biology of Ceratonia siliqua L. (Carob) that are relevant to understanding its ecological characteristics and behaviour. The main topics are presented within the standard framework of the Intern... Read More about International Biological Flora: Ceratonia siliqua.

Effect of cardiolipin on the lamellarity and elongation of liposomes hydrated in PBS (2024)
Journal Article
Piccinini, A., Kohlbrecher, J., Moussaoui, D., Winter, A., & Prévost, S. (in press). Effect of cardiolipin on the lamellarity and elongation of liposomes hydrated in PBS. Journal of Colloid and Interface Science, 669, 844-855. https://doi.org/10.1016/j.jcis.2024.04.211

Lamellarity and shape are important factors in the formation of vesicles and determine their role in biological systems and pharmaceutical applications. Cardiolipin (CL) is a major lipid in many biological membranes and exerts a gr... Read More about Effect of cardiolipin on the lamellarity and elongation of liposomes hydrated in PBS.

Identifying archived insect bulk samples using DNA metabarcoding: A case study using the long-term Rothamsted Insect Survey (2024)
Journal Article
Petsopoulos, D., Cuff, J. P., Bell, J. R., Kitson, J. J. N., Collins, L., Boonham, N., …Evans, D. M. (2024). Identifying archived insect bulk samples using DNA metabarcoding: A case study using the long-term Rothamsted Insect Survey. Environmental DNA, 6(3), e542. https://doi.org/10.1002/edn3.542

Insect populations are declining in many parts of the world, but a lack of long-term monitoring data is impeding our ability to understand and mitigate the causes of insect biodiversity loss. Whilst high-throughput sequencing (HTS) approaches, such a... Read More about Identifying archived insect bulk samples using DNA metabarcoding: A case study using the long-term Rothamsted Insect Survey.

DISRUPTIONS IN LIVELIHOODS, HEALTHCARE ACCESS AND HEALTH OUTCOMES IN WEST AFRICA DURING EMERGING INFECTIOUS DISEASE OUTBREAKS (2024)
Working Paper
Ansumana, R., Bockarie, A. S., Konneh, M., Haider, N., Cadmus, E., Korvah, A., …Alders, R. DISRUPTIONS IN LIVELIHOODS, HEALTHCARE ACCESS AND HEALTH OUTCOMES IN WEST AFRICA DURING EMERGING INFECTIOUS DISEASE OUTBREAKS

Background Outbreaks of infectious diseases like Ebola virus disease, Lassa fever, and COVID-19 have severely strained infrastructural systems and social services across West Africa. We investigated the disruptions caused by emerging outbreaks on acc... Read More about DISRUPTIONS IN LIVELIHOODS, HEALTHCARE ACCESS AND HEALTH OUTCOMES IN WEST AFRICA DURING EMERGING INFECTIOUS DISEASE OUTBREAKS.

Genetic Diversity and Population Structure of the Invasive Oriental Fruit Fly, Bactrocera dorsalis (Diptera: Tephritidae) in Burkina Faso (2024)
Journal Article
Traoré, N., Kientega, M., Maïga, H., Nebié, K., Zida, I., Galizi, R., …Diabaté, A. (2024). Genetic Diversity and Population Structure of the Invasive Oriental Fruit Fly, Bactrocera dorsalis (Diptera: Tephritidae) in Burkina Faso. Insects, 15(5), Article 298. https://doi.org/10.3390/insects15050298

Bactrocera dorsalis Hendel is a highly invasive horticultural pest that is of major economic importance worldwide. In Burkina Faso, it is one of the main insect pests that affects the production and exportation of mangos. Understanding the biology an... Read More about Genetic Diversity and Population Structure of the Invasive Oriental Fruit Fly, Bactrocera dorsalis (Diptera: Tephritidae) in Burkina Faso.

How aphids fly: take off, free flight and implications for short and long distance migration (2024)
Journal Article
Bell, J., & Shephard, G. (2024). How aphids fly: take off, free flight and implications for short and long distance migration. Agricultural and forest entomology,

444 Differential Transcriptome Signatures of Success are Identified within Different Cell Populations used for Treating Cartilage Defects in the Knee (2024)
Presentation / Conference
Tierney, L., Jones, A., McCarthy, H. S., Roberts, S., Tonge, D., & Wright, K. T. (2024, April). 444 Differential Transcriptome Signatures of Success are Identified within Different Cell Populations used for Treating Cartilage Defects in the Knee. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

How aphids fly: take off, free flight and implications for short and long distance migration (2024)
Journal Article
Bell, J. R., & Shephard, G. (in press). How aphids fly: take off, free flight and implications for short and long distance migration. Agricultural and forest entomology, 1-10. https://doi.org/10.1111/afe.12623

An introduction to high‐speed photography and its entomological impact is provided, emphasizing the importance of high frame rates and high resolution. The take‐off and free flight of Drepanosiphum platanoidis and Myzus persicae were studied in still... Read More about How aphids fly: take off, free flight and implications for short and long distance migration.