Skip to main content

Research Repository

Advanced Search

New insights into the application of pair distribution function studies to biogenic and synthetic hydroxyapatites

Arnold, EL; Keeble, DS; Greenwood, CE; Rogers, KD

New insights into the application of pair distribution function studies to biogenic and synthetic hydroxyapatites Thumbnail


Authors

EL Arnold

DS Keeble

KD Rogers



Abstract

Biogenic and synthetic hydroxyapatites are confounding materials whose properties remain uncertain, even after years of study. Pair distribution function (PDF) analysis was applied to hydroxyapatites in the 1970’s and 1980’s, but this area of research has not taken full advantage of the relatively recent advances in synchrotron facilities. Here, synchrotron X-ray PDF analysis is compared to techniques commonly used to characterise hydroxyapatite (such as wide angle X-ray scattering, Fourier-transform infrared spectroscopy and thermogravimetric analysis) for a range of biogenic and synthetic hydroxyapatites with a wide range of carbonate substitution. Contributions to the pair distribution function from collagen, carbonate and finite crystallite size were examined through principal component analysis and comparison of PDFs. Noticeable contributions from collagen were observed in biogenic PDFs when compared to synthetic PDFs (namely r?<?15 Å), consistent with simulated PDFs of collagen structures. Additionally, changes in local structure were observed for PDFs of synthetic hydroxyapatites with differing carbonate content, notably in features near 4 Å, 8 Å and 19 Å. Regression models were generated to predict carbonate substitution from peak position within the PDFs.

Journal Article Type Article
Acceptance Date Sep 14, 2020
Publication Date Nov 11, 2020
Journal Scientific Reports
Print ISSN 2045-2322
Publisher Nature Publishing Group
Peer Reviewed Peer Reviewed
Volume 10
Article Number 19597
DOI https://doi.org/10.1038/s41598-020-73200-2
Publisher URL https://doi.org/10.1038/s41598-020-73200-2

Files







You might also like



Downloadable Citations