Vibrational spectroscopy in stem cell characterisation: is there a niche?

Sulé-Suso, J.; Forsyth, N.R.; Untereiner, V.; Sockalingum, G.D.

Abstract

Vibrational spectroscopy using both infrared and Raman spectroscopies has been used in recent years with the aim to aid clinicians in disease diagnosis. More recently, these techniques have been applied to study stem cell differentiation and to determine stem cell presence in tissues. These studies have demonstrated the potential of these techniques in better characterising stem cell differentiation phenotypes with potential applications in tissue engineering strategies. However, before the translation of vibrational spectroscopy into clinical practice becomes a reality, several issues still need to be addressed. We describe here an overview of the work carried out so far and the problems that might be encountered when using vibrational spectroscopy.

Citation

Sulé-Suso, J., Forsyth, N., Untereiner, V., & Sockalingum, G. (2014). Vibrational spectroscopy in stem cell characterisation: is there a niche?. Trends in Biotechnology, 32(5), 254-262. https://doi.org/10.1016/j.tibtech.2014.03.002

• Journal Article Type: Article
• Online Publication Date: Apr 3, 2014
• Publication Date: 2014-05
• Deposit Date: Jun 13, 2023
• Journal: Trends in Biotechnology
• Print ISSN: 0167-7799
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 32
• Issue: 5
• Pages: 254-262
• DOI: https://doi.org/10.1016/j.tibtech.2014.03.002
• Keywords: Bioengineering; Biotechnology; stem cells; Raman spectroscopy; infrared spectroscopy; embryonic stem cell; mesenchymal stem cell
• Additional Information: This article is maintained by: Elsevier; Article Title: Vibrational spectroscopy in stem cell characterisation: is there a niche?; Journal Title: Trends in Biotechnology; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.tibtech.2014.03.002; Content Type: article; Copyright: Copyright © 2014 Elsevier Ltd. All rights reserved.