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All Outputs (57)

The hip injection trial (HIT) nested qualitative study: experiences of living with hip Osteoarthritis and receiving trial treatments. (2020)
Presentation / Conference Contribution
Holden, M., Hawarden, A., Paskins, Z., Roddy, E., Mallen, C., Jinks, C., & Trial Team, T. H. The hip injection trial (HIT) nested qualitative study: experiences of living with hip Osteoarthritis and receiving trial treatments. Presented at 2020 OARSI World Congress on Osteoarthritis; 30 April-3 May 2020, Messe Wien Exhibition & Congress Center, Vienna, Austria

Purpose: Evidence about the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited. The HIT trial compared ultrasound-guided intra-articular hip injection (USGI) of triamcinolone acetonide and 1% lidocaine hy... Read More about The hip injection trial (HIT) nested qualitative study: experiences of living with hip Osteoarthritis and receiving trial treatments..

O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT) (2020)
Presentation / Conference Contribution
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., Hall, A., Holden, M., Oppong, R., Kigozi, J., Stevenson, K., Menon, A., Roberts, P., Peat, G., Jinks, C., Foster, N. E., Mallen, C. D., & Roddy, E. (2020, April). O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT). Presented at British Society for Rheumatology Annual Conference 2020, Glasgow, Scotland, UK

Background
Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited. The HIT trial compared the clinical and cost-effectiveness of an ultrasound-guided intra-articular hip injection (USGI) of 4... Read More about O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT).

Foot symptom trajectories over seven years and relationship to potential prognostic factors: the clinical assessment study of the foot (2020)
Presentation / Conference Contribution
Marshall, M., Bucknall, M., Rathod-Mistry, T., Thomas, M., Edwards, J., Peat, G., Menz, H. B., & Roddy, E. Foot symptom trajectories over seven years and relationship to potential prognostic factors: the clinical assessment study of the foot. Presented at 2020 OARSI World Congress on Osteoarthritis (30 April-3 May 2020), Messe Wien Exhibition & Congress Center, Vienna, Austria

P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care (2020)
Presentation / Conference Contribution
Watson, L., Belcher, J., Nicholls, E., Chandratre, P., Blagojevic-Bucknall, M., Hider, S., Lawton, S. A., Mallen, C. D., Muller, S., Rome, K., & Roddy, E. P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care

Background
Gout affects 2.5% of adults in the UK but is often poorly managed. It can impair health-related quality of life (HRQOL), yet little is known about which people with gout are at risk of worse outcomes. We investigated factors associated wi... Read More about P142 Factors associated with change in health-related quality of life in people living with gout: a three-year prospective cohort study in primary care.

P143 The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of an open-label, parallel group, randomised controlled trial (2020)
Presentation / Conference Contribution
Burton, C. L., Rathod-Mistry, T., Blagojevic-Bucknall, M., Chesterton, L. S., Davenport, G., Dziedzic, K. S., Jowett, S. M., Myers, H. L., Oppong, R. A., der Windt, D. A. V., Hay, E. M., & Roddy, E. P143 The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of an open-label, parallel group, randomised controlled trial. Presented at British Society for Rheumatology Annual Conference 2020

Background
Patients with mild-to-moderate carpal tunnel syndrome (CTS) are commonly treated with night splints and/or local corticosteroid injection. In the INSTINCTS (INjection versus SplinTing in Carpal Tunnel Syndrome) trial, we previously report... Read More about P143 The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome: 24-month follow-up of an open-label, parallel group, randomised controlled trial.

Association of a Gout Polygenic Risk Score with Disease Severity Phenotypes Amongst Caucasian Gout Patients in Three Independent Cohorts (2019)
Presentation / Conference Contribution
Sumpter, N., Merriman, T., Reynolds, R., Abhishek, A., Andres, M., Dalbeth, N., Doherty, M., Jacobsson, L., Janssen, M., Jansen, T., Joosten, L., Kapetanovic, M., Liote, F., Matsuo, H., McCarthy, G., Perez-Ruiz, F., Riches, P., Richette, P., Roddy, E., Stiburkova, B., …Uhlig, T. (2019, November). Association of a Gout Polygenic Risk Score with Disease Severity Phenotypes Amongst Caucasian Gout Patients in Three Independent Cohorts. Paper presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose:

This study aimed to determine whether a polygenic risk score (PRS) based on gout-associated genetic variants is associated with gout disease severity phenotypes such as age at onset, presence of tophi and flare frequency.

Me... Read More about Association of a Gout Polygenic Risk Score with Disease Severity Phenotypes Amongst Caucasian Gout Patients in Three Independent Cohorts.

Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT) (2019)
Presentation / Conference Contribution
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., Hall, A., Holden, M., Oppong, R., Stevenson, K., Menon, A., Roberts, P., Peat, G., Jinks, C., Foster, N., Mallen, C., & Roddy, E. (2019, November). Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT). Paper presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT).

"If It Was Unicorn Dust I'd Have It Again." Patient Experiences of Hip Osteoarthritis and Treatments in the Hip Injection Trial (2019)
Presentation / Conference Contribution
Jinks, C., Hawarden, A., Roddy, E., Paskins, Z., Mallen, C., & Holden, M. (2019, November). "If It Was Unicorn Dust I'd Have It Again." Patient Experiences of Hip Osteoarthritis and Treatments in the Hip Injection Trial. Presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about "If It Was Unicorn Dust I'd Have It Again." Patient Experiences of Hip Osteoarthritis and Treatments in the Hip Injection Trial.

202 Gout attack trajectories in a 3-year cohort study in primary care (2019)
Presentation / Conference Contribution
Watson, L., Belcher, J., Mallen, C. D., & Roddy, E. 202 Gout attack trajectories in a 3-year cohort study in primary care

Background: Gout affects 2.5% of adults in the UK but is often poorly managed. Whilst the hallmark of gout is recurrent sudden-onset attacks of acute joint pain and swelling, little is known about the pattern (trajectory) of attacks over time. We aim... Read More about 202 Gout attack trajectories in a 3-year cohort study in primary care.

Efficacy of Shoe-Stiffening Inserts for First Metatarsophalangeal Joint Osteoarthritis: Preliminary Findings from the Simple Randomised Controlled Trial (2018)
Presentation / Conference Contribution
Munteanu, S., Landorf, K., McClelland, J., Roddy, E., Cicuttini, F., Shiell, A., Auhl, M., Allan, J., Buldt, A., & Menz, H. B. (2018, October). Efficacy of Shoe-Stiffening Inserts for First Metatarsophalangeal Joint Osteoarthritis: Preliminary Findings from the Simple Randomised Controlled Trial

Background/Purpose: This trial assessed the efficacy of shoe-stiffening inserts for reducing pain associated with first metatarsophalangeal joint (MTPJ) osteoarthritis (OA).

Methods: One hundred participants (45 men 55 women, mean age 57.5, SD 10.... Read More about Efficacy of Shoe-Stiffening Inserts for First Metatarsophalangeal Joint Osteoarthritis: Preliminary Findings from the Simple Randomised Controlled Trial.

FRI0690 Risk of fracture among patients with gout: a population-based cohort study (2017)
Presentation / Conference Contribution
Sultan, A. A., Whittle, R., Muller, S., Roddy, E., Mallen, C., Blagojevic-Bucknall, M., Helliwell, T., Hider, S., & Paskins, Z. (2017, June). FRI0690 Risk of fracture among patients with gout: a population-based cohort study. Poster presented at Annual European Congress of Rheumatology

SAT0672 Risk of fragility fracture among patients with psoriasis: a population based matched cohort study from the united kingdom (2017)
Presentation / Conference Contribution
Paskins, Z., Whittle, R., Sultan, A. A., Muller, S., Helliwell, T., Blagojevic-Bucknall, M., Hider, S., Roddy, E., & Mallen, C. (2017, June). SAT0672 Risk of fragility fracture among patients with psoriasis: a population based matched cohort study from the united kingdom. Poster presented at Annual European Congress of Rheumatology, 14–17 June, 2017

THU0464 A genome-wide association study of gout in people of european ancestry (2017)
Presentation / Conference Contribution
Merriman, T., Cadzow, M., Merriman, M., Phipps-Green, A., Topless, R., Abhishek, A., Andres, M., Bradbury, L., Buchanan, R., Cremin, K., Guzman, E. D., Zoysa, J. D., Doherty, M., Hill, C., Huizinga, T., Jansen, T., Janssen, M., Joosten, L., Kurreeman, F., Lester, S., …Flynn, T. (2017, June). THU0464 A genome-wide association study of gout in people of european ancestry. Paper presented at Annual European Congress of Rheumatology, 14–17 June, 2017

CELEBRATING TEN YEARS OF SUCCESSFUL PATIENT INVOLVEMENT IN RESEARCH OF INFLAMMATORY CONDITIONS (2017)
Presentation / Conference Contribution
Higginbottom, A., Blackburn, S., Campbell, L., Rhodes, C., Taylor, R., Machin, A., Hider, S., Roddy, E., Chew-Graham, C. A., & Dziedzic, K. (2017, June). CELEBRATING TEN YEARS OF SUCCESSFUL PATIENT INVOLVEMENT IN RESEARCH OF INFLAMMATORY CONDITIONS. Poster presented at EULAR: Annual European Congress of Rheumatology 2017, Madrid, Spain

Seeing the light at the end of the carpal tunnel: the challenges of recruiting sites to a clinical trial of an investigational medicinal product in primary care (2017)
Presentation / Conference Contribution
Myers, H., Burton, C., Robinson, M., Davenport, G., Dziedzic, K., van der Windt, D., Chesterton, L., Roddy, E., & Hay, E. (2017, May). Seeing the light at the end of the carpal tunnel: the challenges of recruiting sites to a clinical trial of an investigational medicinal product in primary care. Poster presented at 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials, Liverpool, UK

POPULATION PREVALENCE AND DISTRIBUTION OF ANKLE PAIN AND SYMPTOMATIC RADIOGRAPHIC ANKLE OSTEOARTHRITIS IN COMMUNITY-DWELLING OLDER ADULTS (2016)
Presentation / Conference Contribution
Murray, C. L., Marshall, M., Rathod, T., Menz, H., & Roddy, E. POPULATION PREVALENCE AND DISTRIBUTION OF ANKLE PAIN AND SYMPTOMATIC RADIOGRAPHIC ANKLE OSTEOARTHRITIS IN COMMUNITY-DWELLING OLDER ADULTS. Presented at Rheumatology 2016, SECC Glasgow, UK

Background: OA is highly prevalent in the UK general population, particularly in adults =50 years of age. Numerous epidemiological studies have estimated the population prevalence of OA at joint sites such as the hands, hips and knees, while fewer st... Read More about POPULATION PREVALENCE AND DISTRIBUTION OF ANKLE PAIN AND SYMPTOMATIC RADIOGRAPHIC ANKLE OSTEOARTHRITIS IN COMMUNITY-DWELLING OLDER ADULTS.