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All Outputs (73)

Clinical validation of the Oswestry-Bristol Classification as part of a decision algorithm for trochlear dysplasia surgery (2021)
Journal Article
Sharma, N., Rehmatullah, N., Kuiper, J. H., Gallacher, P., & Barnett, A. J. (2021). Clinical validation of the Oswestry-Bristol Classification as part of a decision algorithm for trochlear dysplasia surgery. The Bone & Joint Journal, 103-B(10), 1586-1594. https://doi.org/10.1302/0301-620x.103b10.bjj-2020-1984.r1

The Oswestry-Bristol Classification (OBC) is an MRI-specific assessment tool to grade trochlear dysplasia. The aim of this study is to validate clinically the OBC by demonstrating its use in selecting treatments that are safe and effective.

Contralateral strength training attenuates muscle performance loss following anterior cruciate ligament (ACL) reconstruction: a randomised-controlled trial. (2021)
Journal Article
Kuiper. (2021). Contralateral strength training attenuates muscle performance loss following anterior cruciate ligament (ACL) reconstruction: a randomised-controlled trial. European Journal of Applied Physiology, 3551-3559. https://doi.org/10.1007/s00421-021-04812-3

PURPOSE: To investigate the effects of cross-education (CE) exercise on strength and performance at 10 and 24 weeks post anterior cruciate ligament (ACL) surgery.

METHODS: Design: randomised controlled trial. N?=?44 ACL-reconstruction patients, r... Read More about Contralateral strength training attenuates muscle performance loss following anterior cruciate ligament (ACL) reconstruction: a randomised-controlled trial..

Identifying Consensus and Open Questions around Assessing or Predicting the Quality and Success of Cartilage Repair: A Delphi Study (2021)
Journal Article
Kuiper. (2021). Identifying Consensus and Open Questions around Assessing or Predicting the Quality and Success of Cartilage Repair: A Delphi Study. Surgeries, 286 - 302. https://doi.org/10.3390/surgeries2030029

<jats:p>A range of surgical techniques have been developed for the repair or regeneration of lesioned cartilage in the human knee and a corresponding array of scoring systems have been created to assess their outcomes. The published literature displa... Read More about Identifying Consensus and Open Questions around Assessing or Predicting the Quality and Success of Cartilage Repair: A Delphi Study.

An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans. (2021)
Journal Article
Wright, K., Roberts, S., & Kuiper, J. (2021). An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans. Cells, https://doi.org/10.3390/cells10081903

Chondrocyte-based cartilage repair strategies, such as articular chondrocyte implantation, are widely used, but few studies addressed the communication between native subchondral bone cells and the transplanted chondrocytes. An indirect co-culture mo... Read More about An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans..

Does statin-treated hyperlipidemia affect rotator cuff healing or muscle fatty infiltration after rotator cuff repair? (2021)
Journal Article
Amit, P., Kuiper, J. H., James, S., & Snow, M. (2021). Does statin-treated hyperlipidemia affect rotator cuff healing or muscle fatty infiltration after rotator cuff repair?. Journal of Shoulder and Elbow Surgery, 2465-2474. https://doi.org/10.1016/j.jse.2021.05.014

PURPOSE: Hyperlipidemia is linked to poor tendon to bone healing and progression of fatty infiltration after rotator cuff repair. Statins effectively treat hyperlipidemia, but it is unknown if they have any potential detrimental effects following rot... Read More about Does statin-treated hyperlipidemia affect rotator cuff healing or muscle fatty infiltration after rotator cuff repair?.

Design and psychometric testing of a new patient-reported outcome measure for ankle treatment (2021)
Journal Article
Sykes, J. G., Bailey, A., Bing, A. J., Kuiper, N. J., Makwana, N., Richardson, J., & Kuiper, J. (2021). Design and psychometric testing of a new patient-reported outcome measure for ankle treatment. Foot, 49, 101793. https://doi.org/10.1016/j.foot.2021.101793

Several outcome scores are used to assess the outcome of ankle surgery, but many are not validated and there is currently no ‘gold-standard’. Consequently, there is demand to develop a new ‘gold-standard’ score to assess ankle surgery. The study aim... Read More about Design and psychometric testing of a new patient-reported outcome measure for ankle treatment.

Mechano-driven regeneration predicts response variations in large animal model based on scaffold implantation site and individual mechano-sensitivity (2021)
Journal Article
Kuiper. (2021). Mechano-driven regeneration predicts response variations in large animal model based on scaffold implantation site and individual mechano-sensitivity. BONE, https://doi.org/10.1016/j.bone.2020.115769

It is well founded that the mechanical environment may regulate bone regeneration in orthopedic applications. The purpose of this study is to investigate the mechanical contributions of the scaffold and the host to bone regeneration, in terms of subj... Read More about Mechano-driven regeneration predicts response variations in large animal model based on scaffold implantation site and individual mechano-sensitivity.

Evaluating patient perspectives on participating in scientific research and clinical trials for the treatment of spinal cord injury (2021)
Journal Article
Bahsoun, S., Kuiper, J., Hulme, C., Twigg, A., El Masri, W., Glass, C., …Wright, K. (2021). Evaluating patient perspectives on participating in scientific research and clinical trials for the treatment of spinal cord injury. Scientific reports, 11, Article 4361. https://doi.org/10.1038/s41598-021-83211-2

A questionnaire was developed to evaluate patients' perspective on research aimed at improving functions and overcoming complications associated with spinal cord injury (SCI). The first three sections were based on published and validated assessment... Read More about Evaluating patient perspectives on participating in scientific research and clinical trials for the treatment of spinal cord injury.

Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach? (2021)
Journal Article
Garcia, J., McCarthy, H. S., Kuiper, J. H., Melrose, J., & Roberts, S. (2021). Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?. Biomolecules, 11(1), Article ARTN 92. https://doi.org/10.3390/biom11010092

Articular cartilage is considered to have limited regenerative capacity, which has led to the search for therapies to limit or halt the progression of its destruction. Perlecan, a multifunctional heparan sulphate (HS) proteoglycan, promotes embryonic... Read More about Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?.

Biomechanical Evaluation Comparing Pulvertaft Weave and Side-to-Side Tenorrhaphy Using Porcine Tendons. (2020)
Journal Article
Kuiper. (2020). Biomechanical Evaluation Comparing Pulvertaft Weave and Side-to-Side Tenorrhaphy Using Porcine Tendons. https://doi.org/10.1142/S2424835520500484

Background: Pulvertaft Weave (PTW) is an established method of tenorrhapy in tendon transfers. Previous studies have suggested that a Side-to-Side (STS) tenorrhapy is easier to perform has the same advantages and has greater load to failure, ultimate... Read More about Biomechanical Evaluation Comparing Pulvertaft Weave and Side-to-Side Tenorrhaphy Using Porcine Tendons..

Characterization of regional meniscal cell and chondrocyte phenotypes and chondrogenic differentiation with histological analysis in osteoarthritic donor-matched tissues (2020)
Journal Article
Wang, J., Roberts, S., Kuiper, J., Zhang, W., Garcia, J., Cui, Z., & Wright, K. (2020). Characterization of regional meniscal cell and chondrocyte phenotypes and chondrogenic differentiation with histological analysis in osteoarthritic donor-matched tissues. Scientific reports, 10, Article 21658. https://doi.org/10.1038/s41598-020-78757-6

Meniscus degeneration is closely related to the progression of knee osteoarthritis (OA). However, there is currently a lack of quantitative and objective metrics to assess OA meniscal cell phenotypes. In this study we investigated the phenotypic mark... Read More about Characterization of regional meniscal cell and chondrocyte phenotypes and chondrogenic differentiation with histological analysis in osteoarthritic donor-matched tissues.

Soft Tissue Radiological Knee (SToRK) Index: An observational cohort study to produce an index that quantifies the magnitude of soft tissue around the knee using standard radiographs (2020)
Journal Article
Sajid, S., Kuiper, J. H., Dhawan, R., Banerjee, R., & Lewthwaite, S. (2020). Soft Tissue Radiological Knee (SToRK) Index: An observational cohort study to produce an index that quantifies the magnitude of soft tissue around the knee using standard radiographs. Journal of Clinical Orthopaedics and Trauma, 11, S909-S915. https://doi.org/10.1016/j.jcot.2020.08.001

Scoliosis in paediatric onset spinal cord injuries. (2020)
Journal Article
Kuiper. (2020). Scoliosis in paediatric onset spinal cord injuries. Spinal Cord, https://doi.org/10.1038/s41393-020-0418-6

STUDY DESIGN: This is a retrospective longitudinal review. OBJECTIVE: The purpose of this review was to identify predictors of developing clinical scoliosis and compare between traumatic and neurological aetiologies of SCI. SETTING: This study was co... Read More about Scoliosis in paediatric onset spinal cord injuries..

The Oswestry-Bristol Classification. (2019)
Journal Article
Kuiper. (2019). The Oswestry-Bristol Classification. The Bone & Joint Journal, 102 - 107. https://doi.org/10.1302/0301-620X.102B1.BJJ-2019-0366.R3

AIMS: Trochlear dysplasia is a significant risk factor for patellofemoral instability. The Dejour classification is currently considered the standard for classifying trochlear dysplasia, but numerous studies have reported poor reliability on both pla... Read More about The Oswestry-Bristol Classification..

Isolated medial patellofemoral ligament reconstruction significantly improved quality of life in patients with recurrent patella dislocation: a response to Hiemstra et al.'s letter to the editor. (2019)
Journal Article
Kuiper. (2019). Isolated medial patellofemoral ligament reconstruction significantly improved quality of life in patients with recurrent patella dislocation: a response to Hiemstra et al.'s letter to the editor. Knee Surgery, Sports Traumatology, Arthroscopy, 3735 - 3737. https://doi.org/10.1007/s00167-019-05690-1

Letter to the editor.

Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells. (2019)
Journal Article
Kuiper. (2019). Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells. Journal of Orthopaedic Research, 1303-1309. https://doi.org/10.1002/jor.24184

The study reports the prospective outcome of treating severe recalcitrant fracture nonunion in patients with autologous bone marrow-derived mesenchymal stromal cells (BMSC) from 2003 to 2010 and analyze predictors of union. Autologous BMSC were cultu... Read More about Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells..