All Outputs (74)

Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus. (2016)
Journal Article
Garcia, J., Wright, K., Roberts, S., Herman Kuiper, J., Mangham, C., Richardson, J., & Mennan, C. (2016). Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus. Scientific reports, 6, 24295 -?. https://doi.org/10.1038/srep24295

The infrapatellar fat pad (FP) and synovial fluid (SF) in the knee serve as reservoirs of mesenchymal stromal cells (MSCs) with potential therapeutic benefit. We determined the influence of the donor on the phenotype of donor matched FP and SF derive... Read More about Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus..

Autologous Bone Plug Supplemented With Autologous Chondrocyte Implantation in Osteochondral Defects of the Knee. (2016)
Journal Article
Bhattacharjee, A., McCarthy, H. S., Tins, B., Roberts, S., Kuiper, J. H., Harrison, P. E., & Richardson, J. B. (2016). Autologous Bone Plug Supplemented With Autologous Chondrocyte Implantation in Osteochondral Defects of the Knee. American Journal of Sports Medicine, 44(5), 1249 - 1259. https://doi.org/10.1177/0363546516631739

BACKGROUND: Structural and functional outcome of bone graft with first- or second-generation autologous chondrocyte implantation (ACI) in treating cartilage and subchondral bone defect has not been reported previously. PURPOSE: To evaluate the outcom... Read More about Autologous Bone Plug Supplemented With Autologous Chondrocyte Implantation in Osteochondral Defects of the Knee..

Alternative tension band technique for olecranon fractures: A biomechanical study (2016)
Journal Article
Singh, S., Kuiper, J., Behzadian, A., Madhusudhan, T., & Sinha, A. (2016). Alternative tension band technique for olecranon fractures: A biomechanical study. Injury, 47(2), 294-295. https://doi.org/10.1016/j.injury.2015.12.008

Objectives: To investigate whether an alternative tension band wire technique will produce greater compression and less displacement at olecranon (elbow) fracture sites compared to a standard figure of eight tension band technique. Olecranon fracture... Read More about Alternative tension band technique for olecranon fractures: A biomechanical study.

Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty (2015)
Journal Article
Khan, M., Kuiper, J., Sieniawska, C., & Richardson, J. (2016). Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty. Journal of Orthopaedics, 13(4), 450-454. https://doi.org/10.1016/j.jor.2015.10.006

Background/aims
Cobalt and chromium are released from MOM hips and their precise nature (ions/particles) is not known. Their distribution in serum, plasma, and whole blood may help to determine their nature.

Methods
We measured cobalt and chromi... Read More about Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty.

Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability (2015)
Journal Article
Walter, M., Kohli, N., Major, T., Fuller, H., Wright, K., Kuiper, J., & Johnson, W. (2015). Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability. Journal of Stem Cells and Regenerative Medicine, 11(1), 18-24. https://doi.org/10.46582/jsrm.1101004

Mesenchymal stem cells (MSCs) stimulate angiogenesis within a wound environment and this effect is mediated through paracrine interactions with the endothelial cells present. Here we report that human MSC-conditioned medium (n=3 donors) significantly... Read More about Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability.

The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study (2015)
Journal Article
Kuiper. (2015). The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study. https://doi.org/10.1016/j.knee.2015.03.011

Background
A new twin-peg version of the Oxford knee was introduced in 2003. However, until now there has been no information about its survivorship. The aim of this study was to determine the survivorship, and the patients' perception of outcome ov... Read More about The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study.

ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion (2015)
Journal Article
Roberts, S., Evans, H., Wright, K., van Niekerk, L., Caterson, B., Richardson, J., …Kuiper, J. (2015). ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion. Osteoarthritis and Cartilage, 23(9), 1622-1626. https://doi.org/10.1016/j.joca.2015.05.006

Objective
To evaluate the potential of ADAMTS-4 (aggrecanase -1) activity in synovial fluid (SF) as a biomarker of knee injury and joint disease.

Design
We have measured ADAMTS-4 activity in the synovial fluid of 170 orthopaedic patients with di... Read More about ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion.

Gonadotropin-releasing hormone (GnRH) analogues for premenstrual syndrome (PMS) (2014)
Journal Article
Naheed, B., Uthman, O. A., O'Mahony, F., Kuiper, J. H., & O'Brien, P. M. S. (2014). Gonadotropin-releasing hormone (GnRH) analogues for premenstrual syndrome (PMS). Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd011330

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To evaluate the therapeutic efficacy of GnRH agonists and antagonists in the management of PMS and PMDD.

Hip resurfacing arthroplasty : A new method to assess and quantify learning phase (2014)
Journal Article
AULAKH, T. S., JAYASEKERA, N., SINGH, R., PATEL, A., KUIPER, J. H., & RICHARDSON, J. B. (2014). Hip resurfacing arthroplasty : A new method to assess and quantify learning phase. Acta Orthopaedica Belgica, 80(3), 397-402

Hip resurfacing had initially gained acceptance and popularity as it helps preserve femoral bone stock. In this study we tried to answer the following questions ; 1. Whether there is a learning curve for hip resurfacing ? 2. Is it present in surgeons... Read More about Hip resurfacing arthroplasty : A new method to assess and quantify learning phase.

Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritis (2014)
Journal Article
Cartwright, A., Schmutz, C., Askari, A., Kuiper, J., & Middleton, J. (2014). Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritis. Cytokine, 67(2), 53-59. https://doi.org/10.1016/j.cyto.2014.02.015

Chemokine receptors on leukocytes mediate the recruitment and accumulation of these cells within affected joints in chronic inflammatory diseases such as rheumatoid arthritis (RA). Identification of involved receptors offers potential for development... Read More about Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritis.

Ponseti casting for club foot – above- or below-knee?: A prospective randomised clinical trial (2013)
Journal Article
Maripuri, S. N., Gallacher, P. D., Bridgens, J., Kuiper, J. H., & Kiely, N. T. (2013). Ponseti casting for club foot – above- or below-knee?: A prospective randomised clinical trial. The Bone & Joint Journal, 95-B(11), 1570-1574. https://doi.org/10.1302/0301-620x.95b11.31899

We undertook a randomised clinical trial to compare treatment times and failure rates between above- and below-knee Ponseti casting groups. Eligible children with idiopathic clubfoot, treated using the Ponseti method, were randomised to either below-... Read More about Ponseti casting for club foot – above- or below-knee?: A prospective randomised clinical trial.

The Oswestry Risk Index: An aid in the treatment of metastatic disease of the spine (2013)
Journal Article
Balain, B., Jaiswal, A., Trivedi, J. M., Eisenstein, S. M., Kuiper, J. H., & Jaffray, D. C. (2013). The Oswestry Risk Index: An aid in the treatment of metastatic disease of the spine. The Bone & Joint Journal, 95-B(2), 210-216. https://doi.org/10.1302/0301-620x.95b2.29323

The revised Tokuhashi, Tomita and modified Bauer scores are commonly used to make difficult decisions in the management of patients presenting with spinal metastases. A prospective cohort study of 199 consecutive patients presenting with spinal metas... Read More about The Oswestry Risk Index: An aid in the treatment of metastatic disease of the spine.

No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients (2010)
Journal Article
Kuiper. (2010). No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients. Acta Orthopaedica Belgica, 619 - 627

We performed a prospective, randomised controlled trial to assess the differences in the use of a conventional suction drain, an Autologous Blood Transfusion (ABT) drain and no drain, in 168 patients. There was no significant difference between the d... Read More about No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients.

The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study. (2009)
Journal Article
Kuiper. (2009). The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study. Journal of Orthopaedic Surgery and Research, 17 -?. https://doi.org/10.1186/1749-799X-4-17

BACKGROUND: Disease modifying anti-rheumatic drugs (DMARDs) may interfere with bone healing. Previous studies give conflicting advice regarding discontinuation of these drugs in the peri-operative setting. No consensus exists in current practice espe... Read More about The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study..