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All Outputs (78)

Scoliosis in paediatric onset spinal cord injuries. (2020)
Journal Article
Kuiper. (2020). Scoliosis in paediatric onset spinal cord injuries. Spinal Cord, https://doi.org/10.1038/s41393-020-0418-6

STUDY DESIGN: This is a retrospective longitudinal review. OBJECTIVE: The purpose of this review was to identify predictors of developing clinical scoliosis and compare between traumatic and neurological aetiologies of SCI. SETTING: This study was co... Read More about Scoliosis in paediatric onset spinal cord injuries..

The Oswestry-Bristol Classification. (2019)
Journal Article
Kuiper. (2019). The Oswestry-Bristol Classification. The Bone & Joint Journal, 102 - 107. https://doi.org/10.1302/0301-620X.102B1.BJJ-2019-0366.R3

AIMS: Trochlear dysplasia is a significant risk factor for patellofemoral instability. The Dejour classification is currently considered the standard for classifying trochlear dysplasia, but numerous studies have reported poor reliability on both pla... Read More about The Oswestry-Bristol Classification..

Isolated medial patellofemoral ligament reconstruction significantly improved quality of life in patients with recurrent patella dislocation: a response to Hiemstra et al.'s letter to the editor. (2019)
Journal Article
Kuiper. (2019). Isolated medial patellofemoral ligament reconstruction significantly improved quality of life in patients with recurrent patella dislocation: a response to Hiemstra et al.'s letter to the editor. Knee Surgery, Sports Traumatology, Arthroscopy, 3735 - 3737. https://doi.org/10.1007/s00167-019-05690-1

Letter to the editor.

Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells. (2019)
Journal Article
Kuiper. (2019). Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells. Journal of Orthopaedic Research, 1303-1309. https://doi.org/10.1002/jor.24184

The study reports the prospective outcome of treating severe recalcitrant fracture nonunion in patients with autologous bone marrow-derived mesenchymal stromal cells (BMSC) from 2003 to 2010 and analyze predictors of union. Autologous BMSC were cultu... Read More about Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells..

A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - II: The effects of co-implantation (2019)
Journal Article
Naire, & Kuiper. (2019). A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - II: The effects of co-implantation. Journal of Tissue Engineering, 1-14. https://doi.org/10.1177/2041731419827792

We present a mathematical model of cartilage regeneration after cell therapy, to show how co-implantation of stem cells (mesenchymal stem cells) and chondrocytes into a cartilage defect can impact chondral healing. The key mechanisms involved in the... Read More about A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - II: The effects of co-implantation.

A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - I: The effects of growth factors (2019)
Journal Article
Campbell, K., Kuiper, J., & Naire, S. (2019). A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - I: The effects of growth factors. Journal of Tissue Engineering, 1-16. https://doi.org/10.1177/2041731419827791

Autologous Chondrocyte Implantation is a cell-based therapy for treating chondral defects. The procedure begins by inserting chondrocytes into the defect region. The chondrocytes initiate healing by proliferating and depositing extracellular matrix,... Read More about A mathematical model of cartilage regeneration after chondrocyte and stem cell implantation - I: The effects of growth factors.

Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements (2019)
Journal Article
Kuiper. (2019). Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements. Journal of Clinical Orthopaedics and Trauma, 350-357. https://doi.org/10.1016/j.jcot.2017.12.008

Introduction
40?mm large diameter heads offer the advantages of lesser dislocation rates and better stability while highly cross linked polyethylene have lower wear rates than ultra high molecular weight polyethylene. Studies of the survivorship of... Read More about Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements.

Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy. (2018)
Journal Article
Kuiper, J., & Wright, K. (2018). Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy. European cells & materials, 255 - 267. https://doi.org/10.22203/eCM.v035a18

High hopes have been pinned on regenerative medicine strategies in order to prevent the progression of cartilage damage to osteoarthritis, particularly by autologous chondrocyte implantation (ACI). The loss of chondrocyte phenotype during in vitro mo... Read More about Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy..

External rotation bracing for first-time anterior dislocation of the shoulder: A discontinued randomised controlled trial comparing external rotation bracing with conventional sling (2018)
Journal Article
Chan, S. K., Bentick, K. R., Kuiper, J. H., & Kelly, C. P. (2019). External rotation bracing for first-time anterior dislocation of the shoulder: A discontinued randomised controlled trial comparing external rotation bracing with conventional sling. Shoulder and Elbow, 11(4), 256-264. https://doi.org/10.1177/1758573218768521

Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy (2018)
Journal Article
Sykes, J., Kuiper, J., Richardson, J., Wright, K., & Kuiper, N. (2018). Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy. Osteoarthritis and Cartilage, 26(S1), https://doi.org/10.1016/j.joca.2018.02.221

Purpose
High hopes have been pinned on regenerative medicine strategies to meet the challenge of preventing the progression to osteoarthritis, in particular autologous chondrocyte implantation (ACI). The loss of chondrocyte phenotype during in vitro... Read More about Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy.

The twin peg Oxford knee — Medium term survivorship and surgical principles (2018)
Journal Article
Kuiper. (2018). The twin peg Oxford knee — Medium term survivorship and surgical principles. https://doi.org/10.1016/j.knee.2018.01.001

A multicentre study of single peg Oxford knees reported failure associated with osteoarthritis progression, femoral component loosening, unexplained pain and meniscal bearing dislocation. Suboptimally positioned femoral components and intraoperative... Read More about The twin peg Oxford knee — Medium term survivorship and surgical principles.

Tendon end separation with loading in an Achilles tendon repair model: comparison of non-absorbable vs. absorbable sutures (2017)
Journal Article
Kuiper. (2017). Tendon end separation with loading in an Achilles tendon repair model: comparison of non-absorbable vs. absorbable sutures. Journal of Experimental Orthopaedics, https://doi.org/10.1186/s40634-017-0101-9

Background: Rupture of the Achilles tendon often leads to long-term morbidity, particularly calf weakness associated with tendon elongation. Operative repair of Achilles tendon ruptures leads to reduced tendon elongation. Tendon lengthening is a key... Read More about Tendon end separation with loading in an Achilles tendon repair model: comparison of non-absorbable vs. absorbable sutures.

Similar phenotypes of cells in the repair tissues following microfracture or autologous chondrocyte implantation (2017)
Journal Article
Garcia, J., Hulme, C., Roberts, S., Richardson, J., Kuiper, J., & Wright, K. (2017). Similar phenotypes of cells in the repair tissues following microfracture or autologous chondrocyte implantation. International Journal of Experimental Pathology, 98(3), A23

Introduction

Autologous chondrocyte implantation (ACI) and microfracture are both used in the treatment of cartilage injuries. Previous findings suggest that the efficacy of these two therapies is similar in terms of short-term clinical outcome, h... Read More about Similar phenotypes of cells in the repair tissues following microfracture or autologous chondrocyte implantation.

Efficacy and safety of autologous cell therapies for knee cartilage defects (autologous stem cells, chondrocytes or the two): randomized controlled trial design. (2017)
Journal Article
Richardson, J. B., Wright, K. T., Wales, J., Herman Kuiper, J., McCarthy, H. S., Gallacher, P., …Roberts, S. (2017). Efficacy and safety of autologous cell therapies for knee cartilage defects (autologous stem cells, chondrocytes or the two): randomized controlled trial design. Regenerative Medicine, 12(5), 493-501. https://doi.org/10.2217/rme-2017-0032

AIM: The main aim of this trial is to test the safety and efficacy of autologous stromal/stem cells, chondrocytes or the two combined in the treatment of knee cartilage defects. PATIENTS & METHODS: Patients with symptomatic chondral/osteochondral def... Read More about Efficacy and safety of autologous cell therapies for knee cartilage defects (autologous stem cells, chondrocytes or the two): randomized controlled trial design..

Cartilage harvest elevates sCD14 and MMP-3 in the synovial fluid of the autologous chondrocyte implantation (ACI) treated joint (2017)
Journal Article
Wright, K. T., Wilson, E., Hulme, C., Kuiper, J. H., Gallacher, P., Richardson, J. B., & Roberts, S. (2017). Cartilage harvest elevates sCD14 and MMP-3 in the synovial fluid of the autologous chondrocyte implantation (ACI) treated joint. International Journal of Experimental Pathology, 97(6), A24

Introduction This study aims to examine the impact of the cartilage harvest procedure on synovial fluid biomarkers at the time of autologous chondrocyte implantation (ACI).

Materials and Methods Hyaluronic acid (HA), cartilage oligomeric matrix pr... Read More about Cartilage harvest elevates sCD14 and MMP-3 in the synovial fluid of the autologous chondrocyte implantation (ACI) treated joint.

The absence of detectable ADAMTS-4 (aggrecanase-1) activity in synovial fluid is a predictive indicator of autologous chondrocyte implantation success (2017)
Journal Article
Kuiper, J., Roberts, S., & Wright, K. (2017). The absence of detectable ADAMTS-4 (aggrecanase-1) activity in synovial fluid is a predictive indicator of autologous chondrocyte implantation success. American Journal of Sports Medicine, 1806-1814

Background:
Autologous chondrocyte implantation (ACI) is used worldwide in the treatment of cartilage defects in the knee. Several demographic and injury-specific risk factors have been identified that can affect the success of ACI treatment. Howeve... Read More about The absence of detectable ADAMTS-4 (aggrecanase-1) activity in synovial fluid is a predictive indicator of autologous chondrocyte implantation success.

Surgical treatment for developmental dysplasia of the hip- a single surgeon series of 47 hips with a 7 year mean follow up). (2016)
Journal Article
Kuiper. (2016). Surgical treatment for developmental dysplasia of the hip- a single surgeon series of 47 hips with a 7 year mean follow up)

The treatment of developmental dysplasia of the hip (DDH) in children remains controversial. We describe the clinical and radiological outcomes of  47 hips in 43 children treated with open surgery by one surgeon between 2004 and 2008 for DDH. The mea... Read More about Surgical treatment for developmental dysplasia of the hip- a single surgeon series of 47 hips with a 7 year mean follow up)..