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All Outputs (8)

Lower cell number, lateral defect location and milder grade are associated with improved autologous chondrocyte implantation outcome (2024)
Journal Article
Tierney, L., Kuiper, J. H., Roberts, S., Snow, M., Williams, M., Harrington, M. B., …Wright, K. T. (in press). Lower cell number, lateral defect location and milder grade are associated with improved autologous chondrocyte implantation outcome. Knee Surgery, Sports Traumatology, Arthroscopy, https://doi.org/10.1002/ksa.12433

Purpose
To investigate patient demographic, injury and surgery/treatment-associated factors that can influence the patient-reported outcome (Lysholm score), following autologous chondrocyte implantation (ACI) in a large, ‘real-world’, nonuniform, pr... Read More about Lower cell number, lateral defect location and milder grade are associated with improved autologous chondrocyte implantation outcome.

Journal of Theoretical Biology A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation --Manuscript Draft-- Manuscript Number: JTB-D-23-00814R1 (2024)
Journal Article
Campbell, K., Naire, S., & Kuiper, J.-H. (2024). Journal of Theoretical Biology A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation --Manuscript Draft-- Manuscript Number: JTB-D-23-00814R1. Journal of Theoretical Biology, 592,

Treating bone-cartilage defects is a fundamental clinical problem. The ability of damaged cartilage to self-repair is limited due to its avascularity. Left untreated, these defects can lead to osteoarthritis. Details of osteochondral defect repair ar... Read More about Journal of Theoretical Biology A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation --Manuscript Draft-- Manuscript Number: JTB-D-23-00814R1.

A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation (2024)
Journal Article
Campbell, K., Naire, S., & Kuiper, J.-H. (2024). A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation. Journal of Theoretical Biology, Article 111874. https://doi.org/10.1016/j.jtbi.2024.111874

Treating bone-cartilage defects is a fundamental clinical problem. The ability of damaged cartilage to self-repair is limited due to its avascularity. Left untreated, these defects can lead to osteoarthritis. Details of osteochondral defect repair ar... Read More about A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation.

275 PATIENTS LIVING IN AREAS OF HIGHER SOCIOECONOMIC AREA DEPRIVATION HAVE SIGNIFICANTLY POORER PATIENT-REPORTED OUTCOMES FOLLOWING AUTOLOGOUS CHONDROCYTE IMPLANTATION IN THE UNITED KINGDOM (2024)
Presentation / Conference
Ismael, S., McCarthy, H. S., Williams, M., Barnett, A., Gallacher, P., Jermin, P., …Kuiper, J. H. (2024, April). 275 PATIENTS LIVING IN AREAS OF HIGHER SOCIOECONOMIC AREA DEPRIVATION HAVE SIGNIFICANTLY POORER PATIENT-REPORTED OUTCOMES FOLLOWING AUTOLOGOUS CHONDROCYTE IMPLANTATION IN THE UNITED KINGDOM. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

284 Lower Cell Number Implanted is Consistently Associated with Improved Functional Outcome Post-Autologous Chondrocyte Implantation in Longitudinal Multilevel Modelling Analyses. (2024)
Presentation / Conference
Kuiper, J. H., Dewan, V., Tierney, L., Roberts, S., Harrison, P., Gallacher, P., …Wright, K. T. (2024, April). 284 Lower Cell Number Implanted is Consistently Associated with Improved Functional Outcome Post-Autologous Chondrocyte Implantation in Longitudinal Multilevel Modelling Analyses. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

Assessment of the effectiveness of weight-adjusted antibiotic administration, for reduced duration, in surgical prophylaxis of primary hip and knee arthroplasty. (2024)
Journal Article
Okoro, T., Wan, M., Mukabeta, T. D., Malev, E., Gross, M., Williams, C., …Murnaghan, J. (in press). Assessment of the effectiveness of weight-adjusted antibiotic administration, for reduced duration, in surgical prophylaxis of primary hip and knee arthroplasty. World Journal of Orthopedics, 15(2), 170-179. https://doi.org/10.5312/wjo.v15.i2.170

Prophylactic antibiotics have significantly led to a reduction in the risk of post-operative surgical site infections (SSI) in orthopaedic surgery. The aim of using antibiotics for this purpose is to achieve serum and tissue drug levels that exceed,... Read More about Assessment of the effectiveness of weight-adjusted antibiotic administration, for reduced duration, in surgical prophylaxis of primary hip and knee arthroplasty..