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All Outputs (4)

Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty (2015)
Journal Article
Khan, M., Kuiper, J., Sieniawska, C., & Richardson, J. (2016). Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty. Journal of Orthopaedics, 13(4), 450-454. https://doi.org/10.1016/j.jor.2015.10.006

Background/aims
Cobalt and chromium are released from MOM hips and their precise nature (ions/particles) is not known. Their distribution in serum, plasma, and whole blood may help to determine their nature.

Methods
We measured cobalt and chromi... Read More about Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty.

Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability (2015)
Journal Article
Walter, M., Kohli, N., Major, T., Fuller, H., Wright, K., Kuiper, J., & Johnson, W. (2015). Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability. Journal of Stem Cells and Regenerative Medicine, 11(1), 18-24. https://doi.org/10.46582/jsrm.1101004

Mesenchymal stem cells (MSCs) stimulate angiogenesis within a wound environment and this effect is mediated through paracrine interactions with the endothelial cells present. Here we report that human MSC-conditioned medium (n=3 donors) significantly... Read More about Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability.

ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion (2015)
Journal Article
Roberts, S., Evans, H., Wright, K., van Niekerk, L., Caterson, B., Richardson, J., …Kuiper, J. (2015). ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion. Osteoarthritis and Cartilage, 23(9), 1622-1626. https://doi.org/10.1016/j.joca.2015.05.006

Objective
To evaluate the potential of ADAMTS-4 (aggrecanase -1) activity in synovial fluid (SF) as a biomarker of knee injury and joint disease.

Design
We have measured ADAMTS-4 activity in the synovial fluid of 170 orthopaedic patients with di... Read More about ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion.

The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study (2015)
Journal Article
Kuiper. (2015). The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study. https://doi.org/10.1016/j.knee.2015.03.011

Background
A new twin-peg version of the Oxford knee was introduced in 2003. However, until now there has been no information about its survivorship. The aim of this study was to determine the survivorship, and the patients' perception of outcome ov... Read More about The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study.