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All Outputs (121)

Family-based sexual health intervention for adolescents; A systematic review and meta-analysis (2024)
Journal Article
Mataraarachchi, D., Shepherd, T., Ariyadasa, G., Bajpai, R., Corp, N., & Paudyal, P. (2024). Family-based sexual health intervention for adolescents; A systematic review and meta-analysis. European Journal of Public Health, 34(Supplement_3), https://doi.org/10.1093/eurpub/ckae144.1057

Background Family-based interventions are important in promoting adolescent sexual health outcomes. However, the effectiveness of these interventions in promoting adolescent sexual and reproductive health (ASRH) in Lower and middle-income countries (... Read More about Family-based sexual health intervention for adolescents; A systematic review and meta-analysis.

Exploring online public survey lifestyle datasets with statistical analysis, machine learning and semantic ontology (2024)
Journal Article
Chatterjee, A., Riegler, M. A., Johnson, M. S., Das, J., Pahari, N., Ramachandra, R., …Bajpai, R. (2024). Exploring online public survey lifestyle datasets with statistical analysis, machine learning and semantic ontology. Scientific Reports, 14(1), 1-24. https://doi.org/10.1038/s41598-024-74539-6

Lifestyle diseases significantly contribute to the global health burden, with lifestyle factors playing a crucial role in the development of depression. The COVID-19 pandemic has intensified many determinants of depression. This study aimed to identi... Read More about Exploring online public survey lifestyle datasets with statistical analysis, machine learning and semantic ontology.

Systematic review of prognostic factors for poor outcome in people living with dementia that can be determined from primary care medical records (2024)
Journal Article
Marshall, M., Jordan, J. L., Bajpai, R., Nimmons, D., Smith, T. M., Campbell, P., & Jordan, K. P. (2024). Systematic review of prognostic factors for poor outcome in people living with dementia that can be determined from primary care medical records. BMC Geriatrics, 24(1), Article 801. https://doi.org/10.1186/s12877-024-05389-0

Background: Dementia has a major impact on individuals, their families and caregivers, and wider society. Some individuals experience a faster decline of their function and health compared to others. The objective of this systematic review was to det... Read More about Systematic review of prognostic factors for poor outcome in people living with dementia that can be determined from primary care medical records.

Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis (2024)
Journal Article
Crocker, T. F., Lam, N., Ensor, J., Jordão, M., Bajpai, R., Bond, M., …Clegg, A. (2024). Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis. Health Technology Assessment, 28(48), 224. https://doi.org/10.3310/HNRP2514

Background
Sustaining independence is important for older people, but there is insufficient guidance about which community health and care services to implement.

Objectives
To synthesise evidence of the effectiveness of community services to sus... Read More about Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis.

Identification of variables and development of a prediction model for DIBH eligibility in left-sided breast cancer radiotherapy: a prospective cohort study with temporal validation (2024)
Journal Article
Ahmad, I., Chufal, K. S., Miller, A. A., Bajpai, R., Umesh, P., Sokhal, B. S., …Gairola, M. (in press). Identification of variables and development of a prediction model for DIBH eligibility in left-sided breast cancer radiotherapy: a prospective cohort study with temporal validation. Radiation Oncology, 19(1), Article 115. https://doi.org/10.1186/s13014-024-02512-8

Objective
To identify variables associated with a patients’ ability to reproducibly hold their breath for deep-inspiration breath-hold (DIBH) radiotherapy (RT) and to develop a predictive model for DIBH eligibility.

Methods
This prospective, sin... Read More about Identification of variables and development of a prediction model for DIBH eligibility in left-sided breast cancer radiotherapy: a prospective cohort study with temporal validation.

The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica (2024)
Journal Article
Scott, I. C., Bajpai, R., Hider, S. L., Helliwell, T., Mallen, C. D., & Muller, S. (in press). The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica. Rheumatology Advances in Practice, 8(3), Article rkae081. https://doi.org/10.1093/rap/rkae081

Objective
To examine the association between obesity and patient-reported outcomes measures (PROMs) in a primary care-based cohort of people with polymyalgia rheumatica (PMR).

Methods
The PMR Cohort Study recruited people with incident PMR from... Read More about The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica.

Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials (2024)
Journal Article
Crocker, T. F., Jordão, M., Lam, N., Ramiz, R., Mirza, L., Patel, I., …Walford, R. (2024). Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials. Age and ageing, 53(5), 1-13. https://doi.org/10.1093/ageing/afae102

Introduction Community-based services to sustain independence for older people have varying configurations. A typology of these interventions would improve service provision and research by providing conceptual clarity and enabling the identification... Read More about Development of the Community-based complex Interventions to sustain Independence in Older People (CII-OP) typology: a qualitative synthesis of interventions in randomised controlled trials.

Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review] (2024)
Journal Article
Twohig, H., Bajpai, R., Corp, N., Faux-Nightingale, A., Mallen, C., Robinson, T., …Burton, C. (2024). Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review]. NIHR Open Research, 4(22), https://doi.org/10.3310/nihropenres.13549.1

Background
Children and young people (CYP) may experience prolonged symptoms following COVID-19, commonly termed ‘Long-COVID’. The characteristics of Long-COVID in CYP are unclear, as are the sequalae of acute COVID-19. We aimed to systematically sy... Read More about Long-term outcomes of COVID-19 infection in children and young people: a systematic review and meta-analysis [version 1; peer review: awaiting peer review].

Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study (2024)
Journal Article
Bajpai, R., Partington, R., Muller, S., Forrester, H., Mallen, C. D., Clarson, L., …Roddy, E. (2024). Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study. Rheumatology, Article keae229. https://doi.org/10.1093/rheumatology/keae229

Objectives
Colchicine is commonly used to prevent flares when starting urate-lowering therapy for gout. Patients with gout are frequently concurrently prescribed other medications (such as statins) that may interact with colchicine, increasing the r... Read More about Prognostic factors for colchicine prophylaxis-related adverse events when initiating allopurinol for gout: retrospective cohort study.

Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England (2024)
Journal Article
Lawton, S., Mallen, C., Hussain, Z., Bajpai, R., Muller, S., Holmstrom, C., …Helliwell, T. (2024). Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England. BMJ Open, 14(4), Article e083816. https://doi.org/10.1136/bmjopen-2023-083816

Objectives: To determine General Practice (GP) recording of carer status and the number of patients self-identifying as carers, while self-completing an automated check-in screen prior to a GP consultation.

Design: A descriptive cross-sectional st... Read More about Identifying carers in general practice (STATUS QUO): a multicentre, cross-sectional study in England.

Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. (2024)
Journal Article
Muller, S., Bailey, J., Bajpai, R., Helliwell, T., Harrisson, S. A., Whittle, R., …Ashworth, J. (in press). Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. PAIN, https://doi.org/10.1097/j.pain.0000000000003239

Growing evidence from pharmacovigilance data and postmortem toxicology reports highlights the misuse potential of gabapentinoids. This study aimed to investigate the risk of serious adverse outcomes (drug misuse, overdose, major trauma), and their ri... Read More about Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study..

Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study (2024)
Journal Article
Chufal, K., Ahmad, I., Prakash, A., Miller, A., Umesh, P., Koul, V., …Gairola, M. (in press). Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study. Cardio-Oncology, 10(1), Article 21. https://doi.org/10.1186/s40959-024-00225-1

Objectives
To investigate the association between radiotherapy (RT) and cardiac biomarkers in women with left-sided breast cancer.

Methods
This prospective observational study recruited patients with stage I-III left-sided breast cancer without... Read More about Cardiac markers in left-sided breast cancer patients receiving adjuvant radiotherapy: a prospective study.

Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise (2024)
Journal Article
Ahmad, I., Chufal, K. S., Miller, A. A., Bajpai, R., Umesh, P., Dawer, A., …Gairola, M. (in press). Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise. British Journal of Radiology, 97(1157), 913-919. https://doi.org/10.1093/bjr/tqae068

Oligometastatic Non-Small Cell Lung cancer (OMD NSCLC) has been proposed to bridge the spectrum between non-metastatic to widely metastatic states and is perceived as an opportunity for potential cure if removed. Twelve clinical trials on local treat... Read More about Is it too early to recommend local treatment in oligometastatic NSCLC: a plea for equipoise.

Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis (2024)
Journal Article
Crocker, T. F., Ensor, J., Lam, N., Jordão, M., Bajpai, R., Bond, M., …Clegg, A. (2024). Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis. BMJ, 384, Article e077764. https://doi.org/10.1136/bmj-2023-077764

To synthesise evidence of the effectiveness of community based complex interventions, grouped according to their intervention components, to sustain independence for older people. Systematic review and network meta-analysis. Medline, Embase, CINAHL,... Read More about Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis.

Effects of participatory ‘A’rt-Based Activity On ‘Health’ of Older Community-Dwellers: results from a randomized control trial of the Singapore A-Health Intervention (2023)
Journal Article
Ho, A. H. Y., Ma, S. H. X., Tan, M. K. B., Bajpai, R., Goh, S. S. N., Yeo, G., …Beauchet, O. (in press). Effects of participatory ‘A’rt-Based Activity On ‘Health’ of Older Community-Dwellers: results from a randomized control trial of the Singapore A-Health Intervention. Frontiers in Medicine, 10, Article 1238562. https://doi.org/10.3389/fmed.2023.1238562

Introduction: The practice of participatory art has been found to support the promotion, prevention, and management of health across the lifespan. However, clinical trials investigating the benefits of creative activities curated with and conducted i... Read More about Effects of participatory ‘A’rt-Based Activity On ‘Health’ of Older Community-Dwellers: results from a randomized control trial of the Singapore A-Health Intervention.

Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis (2023)
Journal Article
Shivakumar, M., Welsh, V., Bajpai, R., Helliwell, T., Mallen, C., Robinson, M., & Shepherd, T. (2024). Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis. Rheumatology International, 44, 235–247. https://doi.org/10.1007/s00296-023-05500-5

Agricultural workers constitute two-thirds of the population of Low- and Middle-Income Countries (LMIC) and are at increased risk of developing musculoskeletal disorders (MSD) due to high-risk activities. This systematic review and meta-analysis aim... Read More about Musculoskeletal disorders and pain in agricultural workers in Low- and Middle-Income Countries: a systematic review and meta-analysis.

Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink (2023)
Journal Article
Roddy, E., Bajpai, R., Forrester, H., James Partington, R., D Mallen, C., Clarson, L. E., …Muller, S. (2023). Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, ard-2023-224154. https://doi.org/10.1136/ard-2023-224154

Objectives:
To determine the risk of adverse events associated with colchicine or non-steroidal anti-inflammatory drug (NSAID) prophylaxis when initiating allopurinol for gout.

Methods:
We conducted two matched retrospective cohort studies in... Read More about Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink.

The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol (2023)
Journal Article
Cox, N., Hawarden, A., Bajpai, R., Farooq, S., Twohig, H., Muller, S., & Scott, I. C. (2024). The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol. Rheumatology International, 44, 435–440. https://doi.org/10.1007/s00296-023-05450-y

Pain is a major challenge for patients with inflammatory arthritis (IA). Depression and anxiety are common comorbidities in IA, associating with worse outcomes. How they relate to pain is uncertain, with existing systematic reviews (a) mainly conside... Read More about The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol.

Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual-Participant Data Meta-analysis of Randomized Controlled Trials. (2023)
Journal Article
Sathish, T., Khunti, K., Narayan, K. M. V., Mohan, V., Davies, M. J., Yates, T., …Shaw, J. E. (in press). Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual-Participant Data Meta-analysis of Randomized Controlled Trials. Diabetes Care, 46(11), 1903–1907. https://doi.org/10.2337/dc23-0696

To examine whether the effect of conventional lifestyle interventions on type 2 diabetes incidence differs by glucose-defined prediabetes phenotype. We searched multiple databases until 1 April 2023 for randomized controlled trials that recruited peo... Read More about Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual-Participant Data Meta-analysis of Randomized Controlled Trials..