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All Outputs (3)

Tools for the Quality Control of Pharmaceutical Heparin. (2019)
Journal Article
Devlin, A., Mycroft-West, C., Procter, P., Cooper, L., Guimond, S., Andrade De Lima, M., …Skidmore, M. (2019). Tools for the Quality Control of Pharmaceutical Heparin. Medicina, 55, 636 - 636. https://doi.org/10.3390/medicina55100636

Heparin is a vital pharmaceutical anticoagulant drug and remains one of the few naturally sourced pharmaceutical agents used clinically. Heparin possesses a structural order with up to four levels of complexity. These levels are subject to change bas... Read More about Tools for the Quality Control of Pharmaceutical Heparin..

A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease. (2019)
Journal Article
Mycroft-West, C., Cooper, L., Devlin, A., Procter, P., Guimond, S., Guerrini, M., …Skidmore, M. (2019). A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease. Marine Drugs, 17, 293 -293. https://doi.org/10.3390/md17050293

Therapeutic options for Alzheimer's disease, the most common form of dementia, are currently restricted to palliative treatments. The glycosaminoglycan heparin, widely used as a clinical anticoagulant, has previously been shown to inhibit the Alzheim... Read More about A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease..