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Protocol for validation of the Global Scales for Early Development (GSED) for children under 3 years of age in seven countries (2023)
Journal Article
Cavallera, V., Lancaster, G., Gladstone, M., Black, M., McCray, G., Nizar, A., …Janus, M. (2023). Protocol for validation of the Global Scales for Early Development (GSED) for children under 3 years of age in seven countries. BMJ Open, 13(1), Article e062562. https://doi.org/10.1136/bmjopen-2022-062562

Introduction: Children’s early development is affected by caregiving experiences, with lifelong health and well-being implications. Governments and civil societies need population-based measures to monitor children’s early development and ensure that... Read More about Protocol for validation of the Global Scales for Early Development (GSED) for children under 3 years of age in seven countries.

Association of Metformin with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis (2023)
Journal Article
Parveen, R., Mishra, P., Luthra, R., Bajpai, R., & Agarwal, N. (2023). Association of Metformin with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis. Annals of the National Academy of Medical Sciences (India), 59(01), 013-020. https://doi.org/10.1055/s-0042-1760353

Studies have demonstrated high prevalence of mortality in coronavirus disease (COVID-19) patients with type 2 diabetes mellitus; however, the effects of antidiabetic pharmacotherapy on COVID-19 complications need further exploration. The aim of the s... Read More about Association of Metformin with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis.

Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD (2023)
Journal Article
Card, T. R., Nakafero, G., Grainge, M. J., Mallen, C. D., Van-Tam, J. S. N., Williams, H. C., & Abhishek, A. (2023). Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD. American Journal of Gastroenterology, 118(8), 1388-1394. https://doi.org/10.14309/ajg.0000000000002205

INTRODUCTION: To investigate the association between vaccination against coronavirus disease 2019 (COVID-19) and inflammatory bowel disease (IBD) flare. METHODS: Patients with IBD vaccinated against COVID-19 who consulted for disease flare between De... Read More about Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD.

Diagnostic delay in adult inflammatory bowel disease: A systematic review (2023)
Journal Article
Cross, E., Saunders, B., Farmer, A., & Prior, J. (2023). Diagnostic delay in adult inflammatory bowel disease: A systematic review. Indian Journal of Gastroenterology, 42, 40-52. https://doi.org/10.1007/s12664-022-01303-x

BACKGROUND: The extent of diagnostic delay in inflammatory bowel disease (IBD) is incompletely understood. We aimed to understand the extent of diagnostic delay of IBD in adults and identify associations between patient or healthcare characteristics... Read More about Diagnostic delay in adult inflammatory bowel disease: A systematic review.

The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome (2023)
Journal Article
Fu, C. E., Yong, J. N., Ng, C. H., Nah, B., Chew, N. W. S., Chin, Y. H., …Muthiah, M. (2023). The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome. Alimentary pharmacology & therapeutics, 57(9), 979-987. https://doi.org/10.1111/apt.17397

Background/Aims Metabolic syndrome (MetS) affects over one third of the US adult population. Despite its close association with non-alcoholic fatty liver disease (NAFLD), the traditional definition of MetS does not account for the presence of NAFLD.... Read More about The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome.

A qualitative interview study exploring the psychological health impacts of the SPIN-CHAT program among people with systemic sclerosis at the onset of COVID-19: perceptions of trial participants and research team members (2023)
Journal Article
Wurz, A., Duchek, D., Ellis, K., Bansal, M., Carrier, M., Tao, L., …Culos-Reed, S. N. (2024). A qualitative interview study exploring the psychological health impacts of the SPIN-CHAT program among people with systemic sclerosis at the onset of COVID-19: perceptions of trial participants and research team members. Disability and Rehabilitation, 46(3), 533-545. https://doi.org/10.1080/09638288.2023.2169775

Purpose
Explore trial participants’ and research team members’ perceptions of the impact of the videoconference-based, supportive care program (SPIN-CHAT Program) during early COVID-19 for individuals with systemic sclerosis (SSc).

Methods
Data... Read More about A qualitative interview study exploring the psychological health impacts of the SPIN-CHAT program among people with systemic sclerosis at the onset of COVID-19: perceptions of trial participants and research team members.

The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019 (2023)
Journal Article
Mamas. (2023). The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019. Metabolism, 141, Article 155402. https://doi.org/10.1016/j.metabol.2023.155402

Background: A significant proportion of premature deaths globally are related to metabolic diseases in young adults. We examined the global trends and mortality of metabolic diseases in individuals aged below 40 years using data from the Global Burde... Read More about The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019.

Optimising the process of knowledge mobilisation in Communities of Practice: recommendations from a (multi-method) qualitative study (2023)
Journal Article
Swaithes, L., Paskins, Z., Quicke, J., Stevenson, K., Fell, K., & Dziedzic, K. (2023). Optimising the process of knowledge mobilisation in Communities of Practice: recommendations from a (multi-method) qualitative study. Implementation Science Communications, 4, Article 11. https://doi.org/10.1186/s43058-022-00384-1

Background: Communities of Practice (CoPs) offer a strategy for mobilising knowledge and integrating evidence-based interventions into musculoskeletal practice, yet little is known about their practical application in this context. This study aimed t... Read More about Optimising the process of knowledge mobilisation in Communities of Practice: recommendations from a (multi-method) qualitative study.

Histological and Radiological Assessment of Endogenously Generated Repair Tissue In Vivo Following a Chondral Harvest (2023)
Journal Article
McCarthy, H. S., Tins, B., Gallacher, P. D., Jermin, P., Richardson, J. B., Herman Kuiper, J., & Roberts, S. (2023). Histological and Radiological Assessment of Endogenously Generated Repair Tissue In Vivo Following a Chondral Harvest. Cartilage, 48-58. https://doi.org/10.1177/19476035221149523

OBJECTIVE: To examine repair tissue formed approximately 15 months after a chondral harvest in the human knee. DESIGN: Sixteen individuals (12 males, 4 females, mean age 36 ± 9 years) underwent a chondral harvest in the trochlea as a pre-requisite fo... Read More about Histological and Radiological Assessment of Endogenously Generated Repair Tissue In Vivo Following a Chondral Harvest.

Can prognostic factors for indirect muscle injuries in elite football (soccer) players be identified using data from preseason screening? An exploratory analysis using routinely collected periodic health examination records (2023)
Journal Article
Hughes, T., Riley, R., Callaghan, M. J., & Sergeant, J. C. (2023). Can prognostic factors for indirect muscle injuries in elite football (soccer) players be identified using data from preseason screening? An exploratory analysis using routinely collected periodic health examination records. BMJ Open, 13(1), Article e052772. https://doi.org/10.1136/bmjopen-2021-052772

Background: In elite football, periodic health examination (PHE) may be useful for injury risk prediction.

Objective: To explore whether PHE-derived variables are prognostic factors for indirect muscle injuries (IMIs) in elite players.

Design:... Read More about Can prognostic factors for indirect muscle injuries in elite football (soccer) players be identified using data from preseason screening? An exploratory analysis using routinely collected periodic health examination records.

Evaluation of thyroid function monitoring in people treated with lithium: Advice based on real‐world data (2023)
Journal Article
Duce, H. L., Duff, C. J., Zaidi, S., Parfitt, C., Heald, A. H., & Fryer, A. A. (2023). Evaluation of thyroid function monitoring in people treated with lithium: Advice based on real‐world data. Bipolar Disorders, 25(5), 402-409. https://doi.org/10.1111/bdi.13298

INTRODUCTION: Blood test monitoring is essential for management of lithium treatment and NICE guidance recommends 6-monthly serum testing of thyroid function. We examined conformity to these guidelines and impact of monitoring outside these intervals... Read More about Evaluation of thyroid function monitoring in people treated with lithium: Advice based on real‐world data.

Prognostic factors associated with outcome following an epidural steroid injection for disc-related sciatica: a systematic review and narrative synthesis. (2023)
Journal Article
Nagington, A., Foster, N., Snell, K., Konstantinou, K., & Stynes, S. (2023). Prognostic factors associated with outcome following an epidural steroid injection for disc-related sciatica: a systematic review and narrative synthesis. European Spine Journal, https://doi.org/10.1007/s00586-023-07528-4

PURPOSE: Clinical guidelines recommend epidural steroid injection (ESI) as a treatment option for severe disc-related sciatica, but there is considerable uncertainty about its effectiveness. Currently, we know very little about factors that might be... Read More about Prognostic factors associated with outcome following an epidural steroid injection for disc-related sciatica: a systematic review and narrative synthesis..

The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. (2023)
Journal Article
Mamas, M., Scourfield, A., Dale, C., Takhar, R., Carragher, R., Katsoulis, M., …Thygesen, J. (2023). The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. Nature Medicine, 219 - 225. https://doi.org/10.1038/s41591-022-02158-7

How the Coronavirus Disease 2019 (COVID-19) pandemic has affected prevention and management of cardiovascular disease (CVD) is not fully understood. In this study, we used medication data as a proxy for CVD management using routinely collected, de-id... Read More about The impact of the COVID-19 pandemic on cardiovascular disease prevention and management..

The creation of the Global Scales for Early Development (GSED) for children aged 0–3 years: combining subject matter expert judgements with big data (2023)
Journal Article
McCray, G., McCoy, D., Kariger, P., Janus, M., Black, M. M., Chang, S. M., …Gladstone, M. (2023). The creation of the Global Scales for Early Development (GSED) for children aged 0–3 years: combining subject matter expert judgements with big data. BMJ Global Health, 8(1), https://doi.org/10.1136/bmjgh-2022-009827

INTRODUCTION: With the ratification of the Sustainable Development Goals, there is an increased emphasis on early childhood development (ECD) and well-being. The WHO led Global Scales for Early Development (GSED) project aims to provide population an... Read More about The creation of the Global Scales for Early Development (GSED) for children aged 0–3 years: combining subject matter expert judgements with big data.

Temporal Trends in In-Hospital Outcomes Following Unprotected Left-Main Percutaneous Coronary Intervention: An Analysis of 14 522 Cases From British Cardiovascular Intervention Society Database 2009 to 2017 (2023)
Journal Article
Kinnaird, T., Gallagher, S., Farooq, V., Protty, M., Back, L., Devlin, P., …Curzen, N. (2023). Temporal Trends in In-Hospital Outcomes Following Unprotected Left-Main Percutaneous Coronary Intervention: An Analysis of 14 522 Cases From British Cardiovascular Intervention Society Database 2009 to 2017. Circulation: Cardiovascular Interventions, 16(1), Article e012350. https://doi.org/10.1161/CIRCINTERVENTIONS.122.012350

Background: Percutaneous coronary intervention (PCI) is increasingly used as a treatment option for unprotected left main stem artery (unprotected left main stem percutaneous intervention) disease. However, whether patient outcomes have improved over... Read More about Temporal Trends in In-Hospital Outcomes Following Unprotected Left-Main Percutaneous Coronary Intervention: An Analysis of 14 522 Cases From British Cardiovascular Intervention Society Database 2009 to 2017.