All Outputs (6)

Use of hybrid iron oxide-silver nanoparticles for thermo-responsive drug delivery in pancreatic cancer (2020)
Thesis
Ali Asgari, M. (2020). Use of hybrid iron oxide-silver nanoparticles for thermo-responsive drug delivery in pancreatic cancer. (Thesis). Keele University

Pancreatic cancer is the 4th most aggressive cancer in the Western world. There are very little drugs available as chemotherapies for the treatment of pancreatic cancer. Of the ones used, most of them become eliminated by first pass metabolism before... Read More about Use of hybrid iron oxide-silver nanoparticles for thermo-responsive drug delivery in pancreatic cancer.

Development of a novel doxorubicin delivery system for pancreatic cancer (2020)
Thesis
Al-Ameri, J. J. M. (2020). Development of a novel doxorubicin delivery system for pancreatic cancer. (Thesis). Keele University

Pancreatic cancer is considered as the 4th most aggressive cancer in the Western world. There is a direct link between
pancreatic cancer diagnosis and patient age with high occurrence of the disease happening in the 65-75-year age group. The majori... Read More about Development of a novel doxorubicin delivery system for pancreatic cancer.

Antimicrobial nano-ninjas as chaperones of gemcitabine for pancreatic cancer (2019)
Thesis
Foulkes, R. L. (2019). Antimicrobial nano-ninjas as chaperones of gemcitabine for pancreatic cancer. (Thesis). Keele University

Pancreatic cancer is well known for its extremely high death rate, with the current treatments purely used to extend and better the quality of the patient's life instead of providing a “cure”. Because of this, novel drug delivery methods are being lo... Read More about Antimicrobial nano-ninjas as chaperones of gemcitabine for pancreatic cancer.

Characterising microglial activation: refinement and validation of primary in vitro models (2019)
Thesis
Al-Shaheeb, S. (2019). Characterising microglial activation: refinement and validation of primary in vitro models. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413772

Background: Neuroinflammation is common to many neurodegenerative conditions and is principally mediated by microglia. Microglia maintain homeostasis, respond to trauma/infection and can promote repair. This is achieved by switching between surveilla... Read More about Characterising microglial activation: refinement and validation of primary in vitro models.

Hydroxypropylmethacrylamide based thermoresponsive magnetomicelles for controllable drug delivery in pancreatic cancer (2018)
Thesis
Alsuraifi, A. T. Y. (2018). Hydroxypropylmethacrylamide based thermoresponsive magnetomicelles for controllable drug delivery in pancreatic cancer. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/412030

Thermo-responsive polymers are a class of smart polymers that respond to change in temperature. This property makes this type of polymers useful materials in a wide range of applications especially, in the field of drug delivery system. Polymers, whi... Read More about Hydroxypropylmethacrylamide based thermoresponsive magnetomicelles for controllable drug delivery in pancreatic cancer.

The co-administration of anticancer and pro-apoptotic agents as a novel approach in liver cancer therapy (2018)
Thesis
AL-Shakarchi, W. (2018). The co-administration of anticancer and pro-apoptotic agents as a novel approach in liver cancer therapy. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/411465

Hepatocellular carcinoma accounts for 85% of primary liver cancer that are usually characterised by defective or ineffective apoptosis which is considered to be the main cause of cancer progression. In this study, Cytochrome-C which is a pro-apoptoti... Read More about The co-administration of anticancer and pro-apoptotic agents as a novel approach in liver cancer therapy.