Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder

Trent, Simon; Fry, Jonathan P; Ojarikre, Obah A; Davies, William

doi:10.1186/2040-2392-5-21

All Outputs (2)

Genetic and Pharmacological Modulation of the Steroid Sulfatase Axis Improves Response Control; Comparison with Drugs Used in ADHD (2014)
Journal Article
Davies, W., Humby, T., Trent, S., Eddy, J. B., Ojarikre, O. A., & Wilkinson, L. S. (2014). Genetic and Pharmacological Modulation of the Steroid Sulfatase Axis Improves Response Control; Comparison with Drugs Used in ADHD. Neuropsychopharmacology, 39(11), 2622-2632. https://doi.org/10.1038/npp.2014.115

Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder (2014)
Journal Article
Trent, S., Fry, J. P., Ojarikre, O. A., & Davies, W. (2014). Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder. Molecular Autism, 5, Article 21. https://doi.org/10.1186/2040-2392-5-21

Background
The 39,XY*O mouse, which lacks the orthologues of the ADHD and autism candidate genes STS (steroid sulphatase) and ASMT (acetylserotonin O-methyltransferase), exhibits behavioural phenotypes relevant to developmental disorders. The neurob... Read More about Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder.