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Knee osteoarthritis, joint laxity and PROMs following conservative management versus surgical reconstruction for ACL rupture: a meta-analysis (2022)
Journal Article
Migliorini, F., Oliva, F., Eschweiler, J., Torsiello, E., Hildebrand, F., & Maffulli, N. (2023). Knee osteoarthritis, joint laxity and PROMs following conservative management versus surgical reconstruction for ACL rupture: a meta-analysis. British Medical Bulletin, 145(1), 72-87. https://doi.org/10.1093/bmb/ldac029

AbstractIntroductionPatients whose rupture of the anterior cruciate ligament (ACL) can be managed conservatively or undergo reconstruction surgery.Source of dataCurrent scientific literature published in Web of Science, PubMed and Scopus.Areas of agr... Read More about Knee osteoarthritis, joint laxity and PROMs following conservative management versus surgical reconstruction for ACL rupture: a meta-analysis.

Ossification of the posterior capitellum: description of a new pathology and its radiological appearance (2022)
Journal Article
Schneider, M. M., Hollinger, B., Zimmerer, A., Nietschke, R., Michaely, H., Migliorini, F., …Burkhart, K. J. (2023). Ossification of the posterior capitellum: description of a new pathology and its radiological appearance. Archives of Orthopaedic and Trauma Surgery, 143(7), 4019-4029. https://doi.org/10.1007/s00402-022-04689-7

Background: Boxer elbow and handball goalkeeper elbow are causes of impingement characterized by osteophytes formation at the olecranon and coronoid tip as well as their corresponding fossae. Herein, we present another distinct pathology in these pat... Read More about Ossification of the posterior capitellum: description of a new pathology and its radiological appearance.

Does femoroacetabular impingement syndrome affect range of motion? A systematic review with meta-analysis (2022)
Journal Article
Albertoni, D. B., Gianola, S., Bargeri, S., Hoxhaj, I., Munari, A., Maffulli, N., & Castellini, G. (2023). Does femoroacetabular impingement syndrome affect range of motion? A systematic review with meta-analysis. British Medical Bulletin, 145(1), 45-59. https://doi.org/10.1093/bmb/ldac027

AbstractBackgroundIt is unclear whether femoroacetabular impingement syndrome (FAIS) affect hip range of motion (ROM).Sources of dataWe performed a systematic review with meta-analysis searching six electronic databases from inception to March 21, 20... Read More about Does femoroacetabular impingement syndrome affect range of motion? A systematic review with meta-analysis.

Autologous Matrix-Induced Chondrogenesis (AMIC) for Osteochondral Defects of the Talus: A Systematic Review (2022)
Journal Article
Migliorini, F., Maffulli, N., Bell, A., Hildebrand, F., Weber, C., & Lichte, P. (2022). Autologous Matrix-Induced Chondrogenesis (AMIC) for Osteochondral Defects of the Talus: A Systematic Review. Life, 12(11), 1738. https://doi.org/10.3390/life12111738

Autologous matrix-induced chondrogenesis (AMIC) has been advocated for the management of talar osteochondral lesions (OCLs). This systematic review, which was conducted according to the PRISMA 2020 guidelines, investigated the clinical and imaging ef... Read More about Autologous Matrix-Induced Chondrogenesis (AMIC) for Osteochondral Defects of the Talus: A Systematic Review.

Cephalomedullary nailing for reverse oblique intertrochanteric fractures 31A3 (AO/OTA) (2022)
Journal Article
Marsillo, E., Pintore, A., Asparago, G., Oliva, F., & Maffulli, N. (in press). Cephalomedullary nailing for reverse oblique intertrochanteric fractures 31A3 (AO/OTA). Orthopedic Reviews, 14(6), https://doi.org/10.52965/001c.38560

Introduction Reverse oblique intertrochanteric fractures are classified by the Orthopaedic Trauma Association [OTA]/[AO] as 31A3, and account for up to one-third of all hip fractures, and 2–23% of all trochanteric fractures. The treatment of choice o... Read More about Cephalomedullary nailing for reverse oblique intertrochanteric fractures 31A3 (AO/OTA).

Allogenic Umbilical Cord Tissue for Treatment of Knee Osteoarthritis (2022)
Journal Article
Gupta, A., & Maffulli, N. (2022). Allogenic Umbilical Cord Tissue for Treatment of Knee Osteoarthritis. Sports Medicine and Arthroscopy Review, 30(3), 162-165. https://doi.org/10.1097/jsa.0000000000000350

Interest in use of perinatal allogenic tissues including clinical-grade minimally manipulated umbilical cord tissue-derived allograft formulations to treat knee osteoarthritis (OA) patients is increasing. Limited studies have characterized these form... Read More about Allogenic Umbilical Cord Tissue for Treatment of Knee Osteoarthritis.

Osteoarthritis Risks and Sports: An Evidence-based Systematic Review (2022)
Journal Article
Migliorini, F., Maffulli, N., Pintore, A., Ernst, J., Eschweiler, J., Hildebrand, F., & Betsch, M. (in press). Osteoarthritis Risks and Sports: An Evidence-based Systematic Review. Sports Medicine and Arthroscopy Review, 30(3), 118-140. https://doi.org/10.1097/jsa.0000000000000351

Purpose: Regular sports activities are associated with multiple physical and psychological health benefits. However, sports also may lead to injuries and the development of osteoarthritis (OA). This systematic review investigated the association betw... Read More about Osteoarthritis Risks and Sports: An Evidence-based Systematic Review.

Low-Dose NSAIDs Efficacy in Orthopedic Applications (2022)
Journal Article
Oliva, F., Quaranta, M., Cipollaro, L., Conti, V., De Bellis, E., Filippelli, A., & Maffulli, N. (2022). Low-Dose NSAIDs Efficacy in Orthopedic Applications. Sports Medicine and Arthroscopy Review, 30(3), 147-161. https://doi.org/10.1097/jsa.0000000000000353

Non-steroidal anti-inflammatory drugs (NSAIDs) [cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors] and COXIBs (the COX-2 selective inhibitors) may induce several potentially severe and life-threatening issues especially in elderly pati... Read More about Low-Dose NSAIDs Efficacy in Orthopedic Applications.

Therapeutic ultrasound related pain threshold in elite track & field athletes with tibial bone stress injuries (2022)
Journal Article
Malliaropoulos, N., Bikos, G., Tsifountoudis, I., Alaseirlis, D., Christodoulou, D., Padhiar, N., & Maffulli, N. (2023). Therapeutic ultrasound related pain threshold in elite track & field athletes with tibial bone stress injuries. Surgeon, 21(4), 225-229. https://doi.org/10.1016/j.surge.2022.06.002

Objective
Tibial stress injuries are challenging in terms of early diagnosis, management strategy, and safe return-to-play. In the present study, pain production associated with the application of therapeutic ultrasound (TUS) was used as a primary d... Read More about Therapeutic ultrasound related pain threshold in elite track & field athletes with tibial bone stress injuries.

Osteoarthritis in Athletes Versus Nonathletes: A Systematic Review (2022)
Journal Article
Migliorini, F., Marsilio, E., Torsiello, E., Pintore, A., Oliva, F., & Maffulli, N. (2022). Osteoarthritis in Athletes Versus Nonathletes: A Systematic Review. Sports Medicine and Arthroscopy Review, 30(2), 78-86. https://doi.org/10.1097/jsa.0000000000000339

Introduction: Joint overload and sport-related injuries may accelerate the development of osteoarthritis (OA). A systematic review of the literature was performed to establish the risk of athletes to develop premature OA compared with nonathletes. Ma... Read More about Osteoarthritis in Athletes Versus Nonathletes: A Systematic Review.

Intensive Physical Activity Increases the Risk of Knee and Hip Arthroplasty: A Systematic Review (2022)
Journal Article
Migliorini, F., Pintore, A., Torsiello, E., Oliva, F., Spiezia, F., & Maffulli, N. (2022). Intensive Physical Activity Increases the Risk of Knee and Hip Arthroplasty: A Systematic Review. Sports Medicine and Arthroscopy Review, 30(2), 111-116. https://doi.org/10.1097/jsa.0000000000000340

Purpose: The present study investigated the type of sport and activity level of athletes before they underwent knee and/or hip arthroplasty for osteoarthritis (OA), and compared them with a control group of subjects who did not undergo knee and hip a... Read More about Intensive Physical Activity Increases the Risk of Knee and Hip Arthroplasty: A Systematic Review.

Osteoarthritis of the Knee in Middle-age Athletes: Many Measures are Practiced, but Lack Sound Scientific Evidence (2022)
Journal Article
Quaranta, M., Riccio, I., Oliva, F., & Maffulli, N. (2022). Osteoarthritis of the Knee in Middle-age Athletes: Many Measures are Practiced, but Lack Sound Scientific Evidence. Sports Medicine and Arthroscopy Review, 30(2), 102-110. https://doi.org/10.1097/jsa.0000000000000341

Osteoarthritis of the knee generally affects individuals from the fifth decade, the typical age of middle-age athletes. In the early stages, management is conservative and multidisciplinary. It is advisable to avoid sports with high risk of trauma, b... Read More about Osteoarthritis of the Knee in Middle-age Athletes: Many Measures are Practiced, but Lack Sound Scientific Evidence.

The Influence of Athletes’ Age in the Onset of Osteoarthritis: A Systematic Review (2022)
Journal Article
Migliorini, F., Vecchio, G., Pintore, A., Oliva, F., & Maffulli, N. (2022). The Influence of Athletes’ Age in the Onset of Osteoarthritis: A Systematic Review. Sports Medicine and Arthroscopy Review, 30(2), 97-101. https://doi.org/10.1097/jsa.0000000000000345

Purpose: Whether sport participation is a risk factor for osteoarthritis (OA) development or progression is controversial. Mechanical overload, injuries, genetics, and acquired disorders concur to the onset of OA, with high variability between sports... Read More about The Influence of Athletes’ Age in the Onset of Osteoarthritis: A Systematic Review.

Elderly Runners and Osteoarthritis: A Systematic Review (2022)
Journal Article
Migliorini, F., Marsilio, E., Oliva, F., Hildebrand, F., & Maffulli, N. (2022). Elderly Runners and Osteoarthritis: A Systematic Review. Sports Medicine and Arthroscopy Review, 30(2), 92-96. https://doi.org/10.1097/jsa.0000000000000347

Purpose: The impact of running on the onset of osteoarthritis (OA) is controversial. This study compared the incidence of OA in elderly runners versus nonrunners. Material and Methods: This systematic review was conducted according to the PRISMA guid... Read More about Elderly Runners and Osteoarthritis: A Systematic Review.

Muscle herniae: Conservative and surgical management. Systematic review (2022)
Journal Article
Quaranta, M., Poeta, N., Oliva, F., & Maffulli, N. (2023). Muscle herniae: Conservative and surgical management. Systematic review. Surgeon, 21(3), 181-189. https://doi.org/10.1016/j.surge.2022.02.003

Background
Muscle herniae are often unrecognized. The primary objective of this systematic review is to evaluate the outcomes of conservative and surgical management for muscle herniae. The secondary objective is to define the most appropriate manag... Read More about Muscle herniae: Conservative and surgical management. Systematic review.

Minimally invasive fasciotomy for symptomatic tibialis anterior muscle hernia (2022)
Journal Article
Maffulli, N., Quaranta, M., Poeta, N., Oliva, F., Padhiar, N., & Chan, O. (2023). Minimally invasive fasciotomy for symptomatic tibialis anterior muscle hernia. Surgeon, 21(2), e63-e70. https://doi.org/10.1016/j.surge.2022.01.005

Background
Symptomatic muscle herniae are an uncommon cause of chronic exercise induced leg pain. The most common site for muscle hernia is the tibialis anterior muscle. This study evaluates the outcome of a minimal incision fasciotomy in patients w... Read More about Minimally invasive fasciotomy for symptomatic tibialis anterior muscle hernia.

Prognostic factors in the management of osteonecrosis of the femoral head: A systematic review (2022)
Journal Article
Migliorini, F., Maffulli, N., Baroncini, A., Eschweiler, J., Tingart, M., & Betsch, M. (2023). Prognostic factors in the management of osteonecrosis of the femoral head: A systematic review. Surgeon, 21(2), 85-98. https://doi.org/10.1016/j.surge.2021.12.004

Background
Several hip preserving techniques have been described for the management of osteonecrosis of the femoral head (ONFH). This systematic review identified prognostic factors in the treatment of ONFH that are associated with treatment failure... Read More about Prognostic factors in the management of osteonecrosis of the femoral head: A systematic review.