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Age and biologic survival in patients with moderate-to-severe psoriasis: A cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2025)
Journal Article
Alabas, O., Mason, K. J., Barker, J., Morrison, S., Yiu, Z., Bewley, A., …Zietemann, V. (2025). Age and biologic survival in patients with moderate-to-severe psoriasis: A cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, https://doi.org/10.1093/bjd/ljaf017

The current management of psoriasis does not differentiate between young and old patients in selecting the safest and/or most effective biologic. To explore the effect of age at treatment initiation in response to biologics in patients with moderate-... Read More about Age and biologic survival in patients with moderate-to-severe psoriasis: A cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

Risk of Suicide and Suicidality in Patients with Moderate to Severe Psoriasis: results from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR) (2024)
Journal Article
Williams, K., Lada, G., Reynolds, N. J., Mcelhone, K., Evans, I., Warren, R. B., …Kleyn, C. E. (2024). Risk of Suicide and Suicidality in Patients with Moderate to Severe Psoriasis: results from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR). Clinical and Experimental Dermatology, https://doi.org/10.1093/ced/llae449

Psoriasis is associated with poor mental health and reduced quality of life. Although the high risk for depression in patients with psoriasis is well-established, their suicidality risk is uncertain. Previous studies provide contrasting results and h... Read More about Risk of Suicide and Suicidality in Patients with Moderate to Severe Psoriasis: results from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR).

Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data (2024)
Journal Article
Akthar, M., Mason, K. J., & Scott, I. C. (2024). Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data. Musculoskeletal Care, 22(3), Article e1916. https://doi.org/10.1002/msc.1916

Objective: The Internet has transformed how patients access health information. We examined Google search engine data to understand which aspects of health are most often searched for in combination with inflammatory arthritis (IA). Methods: Using Go... Read More about Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data.

PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2024)
Journal Article
Williams, K., Lada, G., Reynolds, N., Mcelhone, K., Evans, I., Walton, S., …Kleyn, C. E. (2024). PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, 191(Supplement_1), i177-i177. https://doi.org/10.1093/bjd/ljae090.375

Psoriasis is associated with poor mental health, high prevalence of depression and reduced quality of life. However, suicide risk in this group is unclear. Previous meta-analyses have provided conflicting results regarding risk of suicidality outcome... Read More about PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study. (2024)
Journal Article
Ghosal, S., Heron, N., Mason, K., Bailey, J., & Jordan, K. (2024). Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study. British Journal of General Practice (BJGP), BJGP.2023.0684. https://doi.org/10.3399/bjgp.2023.0684

Orlistat is recommended as an adjunct to diet and exercise for weight loss in type 2 diabetes mellitus (T2DM). The aims were to explore (i) associations between patient characteristics and orlistat prescribing and to determine (ii) associations of or... Read More about Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study..

The association of age at psoriasis onset and HLA-C*06:02 with biologic survival in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2023)
Journal Article
Alabas, O. A., Mason, K. J., Yiu, Z. Z. N., Warren, R. B., Dand, N., Barker, J. N., …Warren, R. B. (2024). The association of age at psoriasis onset and HLA-C*06:02 with biologic survival in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, 190(5), 689–700. https://doi.org/10.1093/bjd/ljad481

Background
Few studies have used real-world data to investigate the association between biologic therapy survival and age at psoriasis onset or HLA-C*06:02 status in patients with moderate-to-severe psoriasis. The robustness of these studies is limi... Read More about The association of age at psoriasis onset and HLA-C*06:02 with biologic survival in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study (2023)
Journal Article
Marshall, M., Mason, K. J., Edwards, J. J., Mamas, M. A., Bailey, J., Heron, N., …Jordan, K. P. (2023). Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study. Rheumatology Advances in Practice, 8(1), Article rkad104. https://doi.org/10.1093/rap/rkad104

Objective
Musculoskeletal pain is a common risk factor for co-morbid conditions and might increase the risk of poor outcomes. The objective was to determine whether patients with pre-existing musculoskeletal pain have an increased risk for mortality... Read More about Pre-existing musculoskeletal pain and its association with mortality in newly diagnosed co-morbid conditions: an electronic health record cohort study.

Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study (2023)
Journal Article
Mason, K. J., Alabas, O. A., Dand, N., Warren, R. B., Reynolds, N. J., Barker, J. N. W. N., …Warren, R. (2024). Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study. British Journal of Dermatology, 190(3), 441–444. https://doi.org/10.1093/bjd/ljad446

It is unknown why some psoriasis patients experience long-term effectiveness with their first biologic monotherapy. Our aim was to compare the baseline demographic, disease, genotypic, clinical and lifestyle characteristics of patients with psoriasis... Read More about Characteristics of ‘super responders’ and ‘super nonresponders’ to first biologic monotherapy for psoriasis: a nested case–control study.

Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study (2023)
Journal Article
Png, M. E., Mason, K. J., Marshall, M., Jordan, K. P., Bailey, J., Frisher, M., …Achana, F. (2023). Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study. Current Medical Research and Opinion, 1-8. https://doi.org/10.1080/03007995.2023.2271862

Objective
To investigate the impact of pre-existing painful musculoskeletal conditions on healthcare utilization and costs among patients with five common conditions: acute coronary syndrome (ACS), stroke, cancer, dementia and pneumonia.

Methods... Read More about Estimating the direct healthcare utilization and cost of musculoskeletal pain among people with comorbidity: a retrospective electronic health record study.

Summarizing Evidence of Associations of COVID‐19 With a Future Diagnosis of Inflammatory Rheumatic and Musculoskeletal Diseases: A Rapid Review (2023)
Journal Article
Mudge, H. R., Honey, J. R., Tachoukaft, S., Hider, S. L., Mason, K. J., Welsh, V. K., & Burton, C. (in press). Summarizing Evidence of Associations of COVID‐19 With a Future Diagnosis of Inflammatory Rheumatic and Musculoskeletal Diseases: A Rapid Review. Arthritis Care & Research, 76(1), 40-48. https://doi.org/10.1002/acr.25227

Musculoskeletal symptoms are commonly reported following acute coronavirus disease 2019 (COVID‐19). It is unclear whether those with musculoskeletal symptoms subsequently develop inflammatory rheumatic musculoskeletal disease (iRMD). This review seek... Read More about Summarizing Evidence of Associations of COVID‐19 With a Future Diagnosis of Inflammatory Rheumatic and Musculoskeletal Diseases: A Rapid Review.

Effectiveness and survival of methotrexate versus adalimumab in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2023)
Journal Article
Alabas, O. A., Mason, K. J., Yiu, Z. Z. N., Warren, R. B., Lunt, M., Smith, C. H., …Zietemann, V. (2023). Effectiveness and survival of methotrexate versus adalimumab in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, 189(3), 271–278. https://doi.org/10.1093/bjd/ljad179

Background
Most information on the comparative effectiveness and survival of methotrexate (MTX) and adalimumab (ADA) in the treatment of psoriasis is from randomized control trials and may not translate to the everyday clinical setting.

Objective... Read More about Effectiveness and survival of methotrexate versus adalimumab in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study. (2023)
Journal Article
Welsh, V. K., Mason, K. J., Bailey, J., Bajpai, R., Jordan, K. P., Mallen, C. D., & Burton, C. (2023). Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study. British Journal of General Practice (BJGP), 73(736), BJGP.2022.0648. https://doi.org/10.3399/bjgp.2022.0648

Background
Rheumatic and musculoskeletal diseases (RMDs) are common and generally managed in primary care through supported self-care, physiotherapy, analgesia, and specialist referral where indicated. The COVID-19 pandemic led to abrupt changes in... Read More about Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study..

The impact of the COVID-19 pandemic on referrals to musculoskeletal services from primary care and subsequent incidence of inflammatory rheumatic musculoskeletal disease: an observational study (2023)
Journal Article
Burton, C., Mallen, C., Mason, K., Jordan, K., Welsh, V., Bajpai, R., & Bailey, J. (2023). The impact of the COVID-19 pandemic on referrals to musculoskeletal services from primary care and subsequent incidence of inflammatory rheumatic musculoskeletal disease: an observational study. Rheumatology Advances in Practice, 7(2), Article ARTN rkad044. https://doi.org/10.1093/rap/rkad044

Objectives
To describe the impact of the COVID-19 pandemic upon referral patterns and incident diagnosis of inflammatory rheumatic and musculoskeletal diseases (iRMDs).

Methods
UK primary care data was used to describe referral patterns for pat... Read More about The impact of the COVID-19 pandemic on referrals to musculoskeletal services from primary care and subsequent incidence of inflammatory rheumatic musculoskeletal disease: an observational study.

Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study (2023)
Journal Article
Mason, K. J., Jordan, K. P., Heron, N., Edwards, J. J., Bailey, J., Achana, F. A., …Marshall, M. (2023). Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study. Musculoskeletal Care, 21(3), 749-762. https://doi.org/10.1002/msc.1748

OBJECTIVE: Musculoskeletal painful conditions are a risk factor for cardiovascular disease (CVD), but less is known about whether musculoskeletal pain also worsens prognosis from CVD. The objective was to determine whether patients with musculoskelet... Read More about Musculoskeletal pain and its impact on prognosis following acute coronary syndrome or stroke: A linked electronic health record cohort study.

Effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters and methotrexate for patients with moderate-to-severe psoriasis: a cohort study from BADBIR (2023)
Journal Article
Alabas, O. A., Mason, K. J., Yiu, Z. Z. N., Hampton, P. J., Reynolds, N. J., Owen, C. M., …Study Group, B. (2023). Effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters and methotrexate for patients with moderate-to-severe psoriasis: a cohort study from BADBIR. British Journal of Dermatology, 188(5), 618–627. https://doi.org/10.1093/bjd/ljad004

Background Real-world data evaluating effectiveness and persistence of systemic therapies for patients with psoriasis are limited. Objectives To determine the effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters (FAEs) and met... Read More about Effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters and methotrexate for patients with moderate-to-severe psoriasis: a cohort study from BADBIR.

Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey (2022)
Journal Article
Quirke-McFarlane, S., Weinman, J., Cook, E. S., Yiu, Z. Z. N., Dand, N., Langan, S. M., …Wang, Y.-H. (2023). Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey. British Journal of Dermatology, 188(5), 610-617. https://doi.org/10.1093/bjd/ljac144

Background Nonadherence to immune-modifying therapy is a complex behaviour which, before the COVID-19 pandemic, was shown to be associated with mental health disorders in people with immune-mediated diseases. The COVID-19 pandemic has led to a rise i... Read More about Nonadherence to systemic immune-modifying therapy in people with psoriasis during the COVID-19 pandemic: findings from a global cross-sectional survey.

P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study (2022)
Journal Article
Mason, K. J., Jordan, K. P., Achana, F. A., Bailey, J., Chen, Y., Frisher, M., …Edwards, J. J. (2022). P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.180

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background/Aims</jats:title> <jats:p>There is some evidence of an increased risk of cardiovascular disease in patients with painful musculoskeletal conditions, but it is unclear if musculoskele... Read More about P181 Musculoskeletal pain and prognosis of acute coronary syndrome and cerebrovascular accident: a linked electronic health record cohort study.

Drug survival of biologics across age groups: an analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR study group (2022)
Journal Article
Alabas, O., Mason, K., Yiu, Z., Warren, R., & Griffiths, C. (2022). Drug survival of biologics across age groups: an analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR study group. British Journal of Dermatology (BJD), 186(1),

HLA-C*06:02 allele is associated with higher drug survival in patients with psoriasis on ustekinumab: an analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR and BSTOP study groups (2022)
Journal Article
Alabas, O., Mason, K., Yiu, Z., Warren, R., Dand, N., Barker, J., …Griffiths, C. (2022). HLA-C*06:02 allele is associated with higher drug survival in patients with psoriasis on ustekinumab: an analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR and BSTOP study groups. British Journal of Dermatology, 186(1), e8-e9