All Outputs (9)

Investigation of modified forms of serum C-reactive protein in diabetes mellitus (2019)
Thesis
Mahmood, S. M. (2019). Investigation of modified forms of serum C-reactive protein in diabetes mellitus. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414936

C-reactive protein (CRP) is known to dissociate to its monomeric subunits (mCRP) in vivo. Furthermore, hyperglycaemia associated with diabetes mellitus (DM) results in glycation of serum proteins to a various extent based on their half-life and glyca... Read More about Investigation of modified forms of serum C-reactive protein in diabetes mellitus.

The structure of Lipid A and composition of the oligosaccharides of the lipopolysaccharides of the bacterial species: Veillonella parvula (2019)
Thesis
Pither, M. (2019). The structure of Lipid A and composition of the oligosaccharides of the lipopolysaccharides of the bacterial species: Veillonella parvula. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417815

Veillonella parvula is a Gram-negative bacterium known to be an abundant commensal coloniser of the human gut and mouth; it is linked to progression of childhood immune system but has also been found to be an opportunistic pathogen. Lipopolysaccharid... Read More about The structure of Lipid A and composition of the oligosaccharides of the lipopolysaccharides of the bacterial species: Veillonella parvula.

Changes in human endothelial cells and astrocytes of the blood-brain barrier (BBB) in cerebral malaria: using in vitro BBB models (2019)
Thesis
Andoh, N. E. (2019). Changes in human endothelial cells and astrocytes of the blood-brain barrier (BBB) in cerebral malaria: using in vitro BBB models. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413819

During cerebral malaria (CM), sequestration of Plasmodium falciparum infected red blood cells (PRBC) to the blood-brain barrier (BBB) is associated with BBB disruption and long-term neurological sequelae in CM survivors, possibly linked to the activa... Read More about Changes in human endothelial cells and astrocytes of the blood-brain barrier (BBB) in cerebral malaria: using in vitro BBB models.

Genetic and ecological processes of speciation in the Anopheles coluzzii and Anopheles gambiae sibling species (2019)
Thesis
Dawam, N. N. (2019). Genetic and ecological processes of speciation in the Anopheles coluzzii and Anopheles gambiae sibling species. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414328

Malaria is a leading cause of death, killing thousands every year. Sub-Saharan Africa has the highest mortality rate, with pregnant women and children under the age of five most affected. The culprits responsible for transmission of the disease are m... Read More about Genetic and ecological processes of speciation in the Anopheles coluzzii and Anopheles gambiae sibling species.

Through fog: An autoethnography of childhood emotional neglect. (2019)
Thesis
Blanchard, A. (2019). Through fog: An autoethnography of childhood emotional neglect. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413773

Childhood emotional neglect is increasingly recognised as significant and widespread, potentially linked to adult depression and anxiety, yet it remains hidden, poorly understood, ill-defined, foggy. Less widely researched than other forms of child m... Read More about Through fog: An autoethnography of childhood emotional neglect..

Investigation into the role of small nucleolar RNA U44 in leukaemia (2019)
Thesis
Gawlik, C. (2019). Investigation into the role of small nucleolar RNA U44 in leukaemia. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417894

Small nucleolar RNAs (snoRNAs) are a class of small non-coding RNAs that act as guide RNAs for post-transcriptional chemical modifications of ribosomal and spliceosome RNAs. Recent independent reports have indicated that these small non-coding RNAs a... Read More about Investigation into the role of small nucleolar RNA U44 in leukaemia.

An evaluation of the antiparasitic activities of a novel natural product and open-access Pathogen Box libraries (2019)
Thesis
Hameed, H. N. (2019). An evaluation of the antiparasitic activities of a novel natural product and open-access Pathogen Box libraries. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413079

Using a novel library of natural products isolated from temperate zone plants, the antiparasitic activity of 643 Phytopure library compounds were determined against intraerytrocytic P. falciparum, the blood-stream form of T. b brucei and axenic amast... Read More about An evaluation of the antiparasitic activities of a novel natural product and open-access Pathogen Box libraries.

Biochemical, biophysical, and structural studies of seed proteins from Moringa oleifera and implications for traditional water purification (2019)
Thesis
Moulin, M. (2019). Biochemical, biophysical, and structural studies of seed proteins from Moringa oleifera and implications for traditional water purification. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413067

Moringa oleifera is a tropical plant that belongs to the Moringaceae family and is native to northern India. Moringa oleifera is called The Miracle Tree because many of its parts have valuable applications. In particular, seed extracts from the plant... Read More about Biochemical, biophysical, and structural studies of seed proteins from Moringa oleifera and implications for traditional water purification.

Biophysical studies of dynamic CD4 changes implicated in HIV-1 infection (2019)
Thesis
Channell, J. A. (2019). Biophysical studies of dynamic CD4 changes implicated in HIV-1 infection. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413133

Cluster of differentiation 4 (CD4) is a receptor protein found on the surface of cells of the immune system and is the primary receptor of the human immuno-deficiency virus-1 (HIV-1) envelope glycoprotein 120 (gp120). The extracellular portion of CD4... Read More about Biophysical studies of dynamic CD4 changes implicated in HIV-1 infection.