All Outputs (4)

GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer (2008)
Journal Article
Mourtada-Maarabouni, M., Pickard, M. R., Hedge, V. L., Farzaneh, F., & Williams, G. T. (2009). GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. Oncogene, 28, 195–208. https://doi.org/10.1038/onc.2008.373

Effective control of both cell survival and cell proliferation is critical to the prevention of oncogenesis and to successful cancer therapy. Using functional expression cloning, we have identified GAS5 (growth arrest-specific transcript 5) as critic... Read More about GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer.

Investigation of the roles of novel apoptosis-controlling genes in breast cancer (2008)
Presentation / Conference
Williams, G., Mourtada-Maarabouni, M., Pickard, M., Hedge, V., & Sutherland, A. (2008, May). Investigation of the roles of novel apoptosis-controlling genes in breast cancer. Poster presented at Breast Cancer Research 2008, London, UK

Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5) (2008)
Journal Article
Mourtada-Maarabouni, M., Hedge, V. L., Kirkham, L., Farzaneh, F., & Williams, G. T. (2008). Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5). Journal of Cell Science, 121(7), 939-946. https://doi.org/10.1242/jcs.024646

The control of growth of lymphocyte populations is crucial to the physiological regulation of the immune system, and to the prevention of both leukaemic and autoimmune disease. This control is mediated through modulation of the cell cycle and regulat... Read More about Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5).

Protein phosphatase 4 regulates apoptosis, proliferation and mutation rate of human cells (2008)
Journal Article
Mourtada-Maarabouni, M., & Williams, G. T. (2008). Protein phosphatase 4 regulates apoptosis, proliferation and mutation rate of human cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1783(8), 1490-1502. https://doi.org/10.1016/j.bbamcr.2008.03.005

The proteins which regulate apoptosis are of great importance both in normal cell biological processes and in the development of pathology in the diverse diseases which involve apoptosis dysfunction. The activity of many of these proteins is controll... Read More about Protein phosphatase 4 regulates apoptosis, proliferation and mutation rate of human cells.