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The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol (2017)
Journal Article
Healey, E., Jinks, C., Foster, N., Chew-Graham, Chew-Graham, C., Pincus, T., …McBeth, J. (2017). The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol. Musculoskeletal Care, 16(1), https://doi.org/10.1002/msc.1222

INTRODUCTION: This pilot trial will inform the design and methods of a future full-scale randomized controlled trial (RCT) and examine the feasibility, acceptability and fidelity of the Increasing Physical activity in Older People with chronic Pain (... Read More about The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol.

The effect of variation in interpretation of the La Trobe radiographic foot atlas on the prevalence of foot osteoarthritis in older women: the Chingford general population cohort. (2017)
Journal Article
McQueen, P., Gates, L., Marshall, M., Doherty, M., Arden, N., & Bowen, C. (in press). The effect of variation in interpretation of the La Trobe radiographic foot atlas on the prevalence of foot osteoarthritis in older women: the Chingford general population cohort. Journal of Foot and Ankle Research, 10, Article 54. https://doi.org/10.1186/s13047-017-0239-9

Background: The prevalence of foot osteoarthritis (OA) is much less understood than hip, knee and hand OA. The foot is anatomically complex and different researchers have investigated different joints with lack of methodological standardisation acros... Read More about The effect of variation in interpretation of the La Trobe radiographic foot atlas on the prevalence of foot osteoarthritis in older women: the Chingford general population cohort..

The long-term impact of childhood wartime trauma on anxiety in later life: an exploration of the literature (2017)
Journal Article
(2017). The long-term impact of childhood wartime trauma on anxiety in later life: an exploration of the literature. Mental Health Practice, https://doi.org/10.7748/mhp.2017.e1215

At any point in time up to 10% of people over the age of 65 experience symptoms of anxiety. Yet the effects of anxiety in the older population are under-researched. Paternal separation in childhood has been cited as a factor for psychological well-be... Read More about The long-term impact of childhood wartime trauma on anxiety in later life: an exploration of the literature.

Effect sizes and their variance for AB/BA crossover design studies (2017)
Journal Article
(2017). Effect sizes and their variance for AB/BA crossover design studies. Empirical Software Engineering, 1982 - 2017. https://doi.org/10.1007/s10664-017-9574-5

Vegas et al. IEEE Trans Softw Eng 42(2):120:135 (2016) raised concerns about the use of AB/BA crossover designs in empirical software engineering studies. This paper addresses issues related to calculating standardized effect sizes and their variance... Read More about Effect sizes and their variance for AB/BA crossover design studies.

Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST). (2017)
Journal Article
Barnett, L., Mallen, C., Lewis, A., & Peat, G. (2017). Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST). Trials, 18, 585 - ?. https://doi.org/10.1186/s13063-017-2329-1

BACKGROUND: Selection bias is a concern when designing cluster randomised controlled trials (c-RCT). Despite addressing potential issues at the design stage, bias cannot always be eradicated from a trial design. The application of bias analysis prese... Read More about Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST)..

A Preliminary Core Domain Set for Clinical Trials of Shoulder Disorders: A Report from the OMERACT 2016 Shoulder Core Outcome Set Special Interest Group (2017)
Journal Article
Buchbinder, R., Page, M. J., Huang, H., Verhagen, A. P., Beaton, D., Kopkow, C., …Set Special Interest Group, T. S. C. O. (2017). A Preliminary Core Domain Set for Clinical Trials of Shoulder Disorders: A Report from the OMERACT 2016 Shoulder Core Outcome Set Special Interest Group. Journal of Rheumatology, 44(12), 1880-1883

Objective. The Outcome Measures in Rheumatology (OMERACT) Shoulder Core Outcome Set Special Interest Group (SIG) was established to develop a core outcome set (COS) for clinical trials of shoulder disorders.

Methods. In preparation for OMERACT 201... Read More about A Preliminary Core Domain Set for Clinical Trials of Shoulder Disorders: A Report from the OMERACT 2016 Shoulder Core Outcome Set Special Interest Group.

Predictive and prognostic factors influencing outcomes of rituximab therapy in systemic lupus erythematosus (SLE): A systematic review (2017)
Journal Article
Van Der Windt. (2017). Predictive and prognostic factors influencing outcomes of rituximab therapy in systemic lupus erythematosus (SLE): A systematic review. Seminars in Arthritis and Rheumatism, 384-396. https://doi.org/10.1016/j.semarthrit.2017.04.010

Background
The clinical outcomes following rituximab (RTX) treatment in patients with systemic lupus erythematosus (SLE) is highly variable. We aimed to identify predictive and prognostic factors associated with RTX therapy outcomes in patients with... Read More about Predictive and prognostic factors influencing outcomes of rituximab therapy in systemic lupus erythematosus (SLE): A systematic review.

Exploring the Added Value of Video-Stimulated Recall in Researching the Primary Care Doctor-Patient Consultation: A Process Evaluation (2017)
Journal Article
Paskins, Z., Sanders, T., Croft, P. R., & Hassell, A. B. (2017). Exploring the Added Value of Video-Stimulated Recall in Researching the Primary Care Doctor-Patient Consultation: A Process Evaluation. International Journal of Qualitative Methods, https://doi.org/10.1177/1609406917719623

Background:
Video-stimulated recall (VSR) is a method whereby researchers show research participants a video of their own behavior to prompt and enhance their recall and interpretation after the event, for example, in a postconsultation interview. T... Read More about Exploring the Added Value of Video-Stimulated Recall in Researching the Primary Care Doctor-Patient Consultation: A Process Evaluation.

Real-world use of fumaric acid esters in psoriasis: results from the British Association of Dermatologists Biologic Interventions Register (BADBIR) (2017)
Presentation / Conference
Mason, K. J., Lunt, M., Hunter, H. J., Jabbar-Lopez, Z. K., Kirby, B., Kleyn, C. E., …Grp, B. A. D. B. I. R. S. (2017, November). Real-world use of fumaric acid esters in psoriasis: results from the British Association of Dermatologists Biologic Interventions Register (BADBIR). Paper presented at Psoriasis Gene to Clinic, 8th International Congress, The Queen Elizabeth II Conference Centre, London, UK

CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness (2017)
Report
Bosanquet, K., Adamson, J., Atherton, K., Bailey, D., Baxter, C., Beresford-Dent, J., …Gilbody, S. (in press). CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness. NIHR

Background
Depression in older adults is common and is associated with poor quality of life, increased morbidity and early mortality, and increased health and social care use. Collaborative care, a low-intensity intervention for depression that is s... Read More about CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness.

A real-world comparison of effectiveness and safety outcomes between clinical trial-eligible and -ineligible patients in the British Association of Dermatologists Biologic Interventions Register (BADBIR) (2017)
Presentation / Conference
Mason, K., Barker, J., Smith, C., Hampton, P., Lunt, M., McElhone, K., …Burden, A. (2017, November). A real-world comparison of effectiveness and safety outcomes between clinical trial-eligible and -ineligible patients in the British Association of Dermatologists Biologic Interventions Register (BADBIR). Paper presented at Psoriasis Gene to Clinic, 8th International Congress, The Queen Elizabeth II Conference Centre, London, UK

Hyperglycaemia and the SOAR stroke score in predicting mortality (2017)
Journal Article
McCall, S. J., Alanazi, T. A., Clark, A. B., Musgrave, S. D., Bettencourt-Silva, J. H., Bachmann, M. O., …Myint, P. K. (2018). Hyperglycaemia and the SOAR stroke score in predicting mortality. Diabetes and Vascular Disease Research, 15(2), 114-121. https://doi.org/10.1177/1479164117743034

Background:
We assessed the association between admission blood glucose levels and acute stroke mortality and examined whether there was any incremental value of adding glucose status to the validated acute stroke mortality predictor – the SOAR (str... Read More about Hyperglycaemia and the SOAR stroke score in predicting mortality.

Impact of Access Site Practice on Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention Following Thrombolysis for ST-Segment Elevation Myocardial Infarction in the United Kingdom : An Insight From the British Cardiovascular Intervention Society Dataset (2017)
Journal Article
Rashid, M., Rushton, C. A., Kwok, C. S., Kinnaird, T., Kontopantelis, E., Olier, I., …Mamas, M. (2017). Impact of Access Site Practice on Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention Following Thrombolysis for ST-Segment Elevation Myocardial Infarction in the United Kingdom : An Insight From the British Cardiovascular Intervention Society Dataset. JACC. Cardiovascular interventions, 10(22), 2258 -2265. https://doi.org/10.1016/j.jcin.2017.07.049

Objectives
This study sought to examine the relationship between access site practice and clinical outcomes in patients requiring percutaneous coronary intervention (PCI) following thrombolysis for ST-segment elevation myocardial infarction (STEMI).... Read More about Impact of Access Site Practice on Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention Following Thrombolysis for ST-Segment Elevation Myocardial Infarction in the United Kingdom : An Insight From the British Cardiovascular Intervention Society Dataset.

25 Vascular access site and outcomes among 26,807 CTO-PCI cases from the national angioplasty audit (2017)
Journal Article
Kinnaird, T., Anderson, R., Gallagher, S., Large, A., Strange, J., Ludman, P., …Mamas, M. (2017). 25 Vascular access site and outcomes among 26,807 CTO-PCI cases from the national angioplasty audit. Heart, 103(S7), https://doi.org/10.1136/heartjnl-2017-BCIS.25

Background Use of radial access in chronic total occlusion percutaneous coronary intervention (CTO-PCI) warrants further investigation. Using the BCIS PCI database, access site choice and outcomes after CTO-PCI were assessed.

Methods Data were ana... Read More about 25 Vascular access site and outcomes among 26,807 CTO-PCI cases from the national angioplasty audit.

Intentional and Unintentional Medication Non-Adherence in Psoriasis: The Role of Patients' Medication Beliefs and Habit Strength (2017)
Journal Article
Thorneloe, R. J., Griffiths, C. E., Emsley, R., Ashcroft, D. M., Cordingley, L., Biologic Interventions Register, B. A. O. D., …Warren, R. (2018). Intentional and Unintentional Medication Non-Adherence in Psoriasis: The Role of Patients' Medication Beliefs and Habit Strength. Journal of Investigative Dermatology, 138(4), 785 - 794. https://doi.org/10.1016/j.jid.2017.11.015

Medication non-adherence is a missed opportunity for therapeutic benefit. We assessed "real-world" levels of self-reported non-adherence to conventional and biologic systemic therapies used for psoriasis and evaluated psychological and biomedical fac... Read More about Intentional and Unintentional Medication Non-Adherence in Psoriasis: The Role of Patients' Medication Beliefs and Habit Strength.

Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort (2017)
Journal Article
Konstantinou, K., Dunn, K., Ogollah, R., Lewis, M., Van Der Windt, D., Hay, E., & Study Team, A. (2017). Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort. Spine Journal, 1030-1040. https://doi.org/10.1016/j.spinee.2017.10.071

Background Context
Evidence is lacking on the prognosis and prognostic factors of back-related leg pain and sciatica in patients seeing their primary care physicians. This evidence could guide timely appropriate treatment and referral decisions.... Read More about Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.

An innovative long final year assistantship in general practice: description and evaluation (2017)
Journal Article
McKinley, R. K., Bartlett, M., Gay, S., Gibson, S., Panesar, A., & Webb, M. (2017). An innovative long final year assistantship in general practice: description and evaluation. Education for Primary Care, 35-42. https://doi.org/10.1080/14739879.2017.1399829

We describe and evaluate an innovative immersive 15 week final year assistantship in general practice. Evaluation data was taken from five years of routinely collected School data and available national comparative data. The assistantship aims to ena... Read More about An innovative long final year assistantship in general practice: description and evaluation.