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All Outputs (329)

What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study (2017)
Journal Article
Liddle, J., Bartlam, R., Mallen, C. D., Mackie, S. L., Prior, J. A., Helliwell, T., & Richardson, J. C. (2017). What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study. BMJ Open, 7(8), e017073 -?. https://doi.org/10.1136/bmjopen-2017-017073

OBJECTIVES: Clinical management of giant cell arteritis (GCA) involves balancing the risks and burdens arising from the disease with those arising from treatment, but there is little research on the nature of those burdens. We aimed to explore the im... Read More about What is the impact of giant cell arteritis on patients’ lives? A UK qualitative study.

Towards Accurate Predictions of Customer Purchasing Patterns (2017)
Conference Proceeding
Valero-Fernandez, R., Collins, D. J., Lam, K., Rigby, C., & Bailey, J. (2017). Towards Accurate Predictions of Customer Purchasing Patterns. . https://doi.org/10.1109/CIT41763.2017

range of algorithms was used to classify online retail customers of a UK company using historical transaction data. The predictive capabilities of the classifiers were assessed using linear regression, Lasso and regression trees. Unlike most related... Read More about Towards Accurate Predictions of Customer Purchasing Patterns.

First‐line uterotonics for treating postpartum haemorrhage: a systematic review and network meta‐analysis (2017)
Journal Article
Parry Smith, W. R., Gallos, I. D., Williams, H. M., Widmer, M., Angolkar, M., Tobias, A., …Coomarasamy, A. (2017). First‐line uterotonics for treating postpartum haemorrhage: a systematic review and network meta‐analysis. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD012754

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

Primary

To assess the relative effectiveness and produce a clinically meaningful hierarchy of first‐line uterotonic drugs for the treatment of postpartum ha... Read More about First‐line uterotonics for treating postpartum haemorrhage: a systematic review and network meta‐analysis.

Association of religion and cultural tradition with alcohol use among some tribal communities of Arunachal Pradesh, India. (2017)
Journal Article
Bajpai. (2017). Association of religion and cultural tradition with alcohol use among some tribal communities of Arunachal Pradesh, India. Journal of Ethnicity in Substance Abuse, 1 - 13. https://doi.org/10.1080/15332640.2017.1355766

Arunachal Pradesh, a land of high mountains and dense forest, is home to many tribal communities, which comprise two thirds of the state's population. Alcohol is one of the common addictive substances used traditionally among them despite much awaren... Read More about Association of religion and cultural tradition with alcohol use among some tribal communities of Arunachal Pradesh, India..

Management of Acute Stroke in the Older Person. (2017)
Journal Article
Parr, E., Ferdinand, P., & Roffe, C. (2017). Management of Acute Stroke in the Older Person. Geriatrics, 2(3), Article 27. https://doi.org/10.3390/geriatrics2030027

The majority of people who suffer a stroke are older adults. The last two decades have brought major progress in the diagnosis and management of stroke, which has led to significant reductions in mortality, long-term disability, and the need for inst... Read More about Management of Acute Stroke in the Older Person..

A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects. (2017)
Journal Article
(2017). A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects. Biometrics, 548 - 556. https://doi.org/10.1111/biom.12762

Random-effects meta-analyses are very commonly used in medical statistics. Recent methodological developments include multivariate (multiple outcomes) and network (multiple treatments) meta-analysis. Here, we provide a new model and corresponding est... Read More about A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects..

mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review (2017)
Journal Article
Gire, N., Farooq, S., Naeem, F., Duxbury, J., McKeown, M., Kundi, P. S., …Husain, N. mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review. mHealth, 3, 33-33. https://doi.org/10.21037/mhealth.2017.07.03

The relative burden of mental health disorders is increasing globally, in terms of prevalence and disability. There is limited data available to guide treatment choices for clinicians in low resourced settings, with mHealth technologies being a poten... Read More about mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review.

'Knowledge leech' to 'part of the team': students' learning in rural communities of practice. (2017)
Journal Article
Rees. (2017). 'Knowledge leech' to 'part of the team': students' learning in rural communities of practice. Education for Primary Care, 5-10. https://doi.org/10.1080/14739879.2017.1362664

BACKGROUND: Keele Medical School has a small accommodation hub for students placed within ten associated general practices in a predominantly rural area of England. Groups of up to eleven final year students spend fifteen weeks learning generic and t... Read More about 'Knowledge leech' to 'part of the team': students' learning in rural communities of practice..

Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992–2013 (2017)
Journal Article
Yu, D., Jordan, K., Bedson, J., Englund, M., Blyth, F., Turkiewicz, A., …Peat, G. (2017). Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992–2013. Rheumatology, 56(11), 1902-1917. https://doi.org/10.1093/rheumatology/kex270

Objective
To determine recent trends in the rate and management of new cases of OA presenting to primary healthcare using UK nationally representative data.

Methods
Using the Clinical Practice Research Datalink we identified new cases of diagnos... Read More about Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992–2013.

TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer (2017)
Journal Article
Gaweł-Bęben, K., Ali, N., Ellis, V., Velasco, G., Poghosyan, Z., Ager, A., & Knäuper, V. (2017). TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer. Cell Biology International, 42(3), 273 - 280. https://doi.org/10.1002/cbin.10832

TMEFF2 is a type I transmembrane protein with two follistatin (FS) and one EGF-like domain over-expressed in prostate cancer; however its biological role in prostate cancer development and progression remains unclear, which may, at least in part, be... Read More about TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer.

Gender Rights and Sustainable Development Education: The case of domestic violence with particular reference to Africa (2017)
Journal Article
(2017). Gender Rights and Sustainable Development Education: The case of domestic violence with particular reference to Africa

Domestic violence is a major global problem with the majority of victims being women and children. Yet, domestic violence is often hidden and/or normalised, especially in ‘peacetime’, everyday contexts. Neoliberal development seems to go hand-in-hand... Read More about Gender Rights and Sustainable Development Education: The case of domestic violence with particular reference to Africa.

Effects of antenatal diet and physical activity on maternal and fetal outcomes: individual patient data meta-analysis and health economic evaluation. (2017)
Journal Article
(2017). Effects of antenatal diet and physical activity on maternal and fetal outcomes: individual patient data meta-analysis and health economic evaluation. Health Technology Assessment, 1 -158. https://doi.org/10.3310/hta21410

BACKGROUND: Diet- and physical activity-based interventions in pregnancy have the potential to alter maternal and child outcomes. OBJECTIVES: To assess whether or not the effects of diet and lifestyle interventions vary in subgroups of women, based o... Read More about Effects of antenatal diet and physical activity on maternal and fetal outcomes: individual patient data meta-analysis and health economic evaluation..

Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data (2017)
Journal Article
(2017). Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data. Statistical Methods in Medical Research, 1896 -1911. https://doi.org/10.1177/0962280215592269

Hierarchical models such as the bivariate and hierarchical summary receiver operating characteristic (HSROC) models are recommended for meta-analysis of test accuracy studies. These models are challenging to fit when there are few studies and/or spar... Read More about Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data.

The British Society for Rheumatology Guideline for the Management of Gout (2017)
Journal Article
Mallen, C., & Roddy, E. (2017). The British Society for Rheumatology Guideline for the Management of Gout. Rheumatology, 56(7), E1-E20. https://doi.org/10.1093/rheumatology/kex156

OBJECTIVES: We previously found large variations in general practitioner (GP) hypertension treatment probability in oldest-old (>80 years) between countries. We wanted to explore whether differences in country-specific cardiovascular disease (CVD) bu... Read More about The British Society for Rheumatology Guideline for the Management of Gout.

Length of Time on Peritoneal Dialysis and Encapsulating Peritoneal Sclerosis — Position Paper for ISPD: 2017 Update (2017)
Journal Article
Brown, E. A., Bargman, J., van Biesen, W., Chang, M., Finkelstein, F. O., Hurst, H., …Woodrow, G. (2017). Length of Time on Peritoneal Dialysis and Encapsulating Peritoneal Sclerosis — Position Paper for ISPD: 2017 Update. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 37(4), 362-374. https://doi.org/10.3747/pdi.2017.00018

Hand dysfunction after transradial artery catheterization for coronary procedures (2017)
Journal Article
Ayyaz Ul Haq, M., Rashid, M., Shing Kwok, C., Wai Wong, C., Nolan, J., & Mamas, M. A. (2017). Hand dysfunction after transradial artery catheterization for coronary procedures. World Journal of Cardiology, 9(7), 609-619. https://doi.org/10.4330/wjc.v9.i7.609

AIM
To sythesize the available literature on hand dysfunction after transradial catheterization.

METHODS
We searched MEDLINE and EMBASE. The search results were reviewed by two independent judicators for studies that met the inclusion criteria a... Read More about Hand dysfunction after transradial artery catheterization for coronary procedures.

Increase in body weight over a two-year period is associated with an increase in midfoot pressure and foot pain (2017)
Journal Article
(2017). Increase in body weight over a two-year period is associated with an increase in midfoot pressure and foot pain. Journal of Foot and Ankle Research, https://doi.org/10.1186/s13047-017-0214-5

Background
There is a well-recognised relationship between body weight, plantar pressures and foot pain, but the temporal association between these factors is unknown. The aim of this study was to investigate the relationships between increasing wei... Read More about Increase in body weight over a two-year period is associated with an increase in midfoot pressure and foot pain.

Vitamin K antagonists versus low-molecular-weight heparin for the long term treatment of symptomatic venous thromboembolism. (2017)
Journal Article
(2017). Vitamin K antagonists versus low-molecular-weight heparin for the long term treatment of symptomatic venous thromboembolism. Cochrane Database of Systematic Reviews, CD002001 - ?. https://doi.org/10.1002/14651858.CD002001.pub3

BACKGROUND: People with venous thromboembolism (VTE) generally are treated for five days with intravenous unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH), followed by three months of vitamin K antagonists (VKAs). Treatment... Read More about Vitamin K antagonists versus low-molecular-weight heparin for the long term treatment of symptomatic venous thromboembolism..