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All Outputs (574)

Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR) (2020)
Journal Article
Littlewood, C., Bateman, M., Butler-Walley, S., Bathers, S., Bromley, K., Lewis, M., …Foster, N. E. (2020). Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR). Clinical Rehabilitation, 35(6), 829-839. https://doi.org/10.1177/0269215520978859

OBJECTIVE: To evaluate the feasibility of a multi-centre randomised controlled trial to compare the clinical and cost-effectiveness of early patient-directed rehabilitation versus standard rehabilitation following surgical repair of the rotator cuff... Read More about Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR).

Radiation protection in the cardiac catheterisation lab: best practice (2020)
Journal Article
Roguin, A., & Nolan, J. (2021). Radiation protection in the cardiac catheterisation lab: best practice. Heart, 107(1), 76-82. https://doi.org/10.1136/heartjnl-2019-316369

Occupational doses of radiation in cardiac procedures guided by fluoroscopy are the highest registered among medical staff using X-rays.1–5 Electrophysiologists and interventional cardiologists are the group with the highest exposure. Patient and ope... Read More about Radiation protection in the cardiac catheterisation lab: best practice.

'As easy as riding a bike': a systematic review of injuries and illness in road cycling. (2020)
Journal Article
Rooney, D., Sarriegui, I., & Heron, N. (2020). 'As easy as riding a bike': a systematic review of injuries and illness in road cycling. BMJ Open Sport & Exercise Medicine, e000840 - ?. https://doi.org/10.1136/bmjsem-2020-000840

Objectives: To allow the implementation of effective injury and illness prevention programmes for road cyclists, we wanted to first identify the injury/illness burden to this group of athletes. We, therefore, undertook a systematic review of all repo... Read More about 'As easy as riding a bike': a systematic review of injuries and illness in road cycling..

Dementia Research Activity in Sri Lanka: A Review (2020)
Journal Article
Abhayasinghe, K., Dissanayake, L., Saunders, B., Campbell, P., & Sumathipala, A. (2020). Dementia Research Activity in Sri Lanka: A Review. Journal of Neurodegenerative Disorders, 3(1), 89-100. https://doi.org/10.36959/459/603

Background: As a result of the global rise in life expectancy, dementia has become a major global health concern; it is considered to be one of the most burdensome conditions of later life. Despite 66% of older adults with dementia living in Low-and-... Read More about Dementia Research Activity in Sri Lanka: A Review.

Penalisation and shrinkage methods can produce unreliable clinical prediction models especially when sample size is small (2020)
Journal Article
(2020). Penalisation and shrinkage methods can produce unreliable clinical prediction models especially when sample size is small. Journal of Clinical Epidemiology, 88-96. https://doi.org/10.1016/j.jclinepi.2020.12.005

Objectives
When developing a clinical prediction model, penalization techniques are recommended to address overfitting, as they shrink predictor effect estimates toward the null and reduce mean-square prediction error in new individuals. However, sh... Read More about Penalisation and shrinkage methods can produce unreliable clinical prediction models especially when sample size is small.

Patients' Views on the Implementation Potential of a Stratified Treatment Approach for Low Back Pain in Germany: A Qualitative Study. (2020)
Journal Article
Karstens, S., Lang, S., & Saunders, B. (2020). Patients' Views on the Implementation Potential of a Stratified Treatment Approach for Low Back Pain in Germany: A Qualitative Study. Health Services Insights, 13, https://doi.org/10.1177/1178632920977894

Stratified care for low back pain (LBP) has been shown to be clinically- and cost-effective in the UK, but its transferability to the German healthcare system is unknown. This study explores LBP patients' perspectives regarding future implementation... Read More about Patients' Views on the Implementation Potential of a Stratified Treatment Approach for Low Back Pain in Germany: A Qualitative Study..

A note on estimating the Cox-Snell R2 from a reported C statistic (AUROC) to inform sample size calculations for developing a prediction model with a binary outcome. (2020)
Journal Article
(2020). A note on estimating the Cox-Snell R2 from a reported C statistic (AUROC) to inform sample size calculations for developing a prediction model with a binary outcome. Statistics in Medicine, https://doi.org/10.1002/sim.8806

In 2019 we published a pair of articles in Statistics in Medicine that describe how to calculate the minimum sample size for developing a multivariable prediction model with a continuous outcome, or with a binary or time-to-event outcome. As for any... Read More about A note on estimating the Cox-Snell R2 from a reported C statistic (AUROC) to inform sample size calculations for developing a prediction model with a binary outcome..

Percutaneous coronary intervention in octogenarians: A risk scoring system to predict 30-day outcomes in the elderly. (2020)
Journal Article
Mamas. (2020). Percutaneous coronary intervention in octogenarians: A risk scoring system to predict 30-day outcomes in the elderly. Catheterization and Cardiovascular Interventions, 1300 - 1307. https://doi.org/10.1002/ccd.29406

OBJECTIVE: Octogenarians are a high-risk group presenting for percutaneous coronary intervention (PCI). We aimed to create a 30-day mortality risk model for octogenarians presenting with both acute coronary syndrome (ACS) and chronic stable angina (C... Read More about Percutaneous coronary intervention in octogenarians: A risk scoring system to predict 30-day outcomes in the elderly..

A qualitative exploration of two risk calculators using video-recorded NHS health check consultations (2020)
Journal Article
(2020). A qualitative exploration of two risk calculators using video-recorded NHS health check consultations. BMC Family Practice, https://doi.org/10.1186/s12875-020-01315-6

<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>The aim of the study was to explore practitioner-patient interactions and patient responses when using QRISK®2 or JBS3 cardiovascular disease (CVD) risk calculato... Read More about A qualitative exploration of two risk calculators using video-recorded NHS health check consultations.

The LENT index predicts 30 day outcomes following hospitalization for heart failure (2020)
Journal Article
Mamas. (2020). The LENT index predicts 30 day outcomes following hospitalization for heart failure. ESC Heart Failure, https://doi.org/10.1002/ehf2.13109

AIMS: The LE index (Length of hospitalization plus number of Emergent visits =6 months) predicts 30 day all-cause readmission or death following hospitalization for heart failure (HF). We combined N-terminal pro-B type natriuretic peptide (NT-proBNP)... Read More about The LENT index predicts 30 day outcomes following hospitalization for heart failure.

Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register. (2020)
Journal Article
Iskandar, I., Warren, R., Lunt, M., Mason, K., Evans, I., McElhone, K., …Ashcroft, D. (2020). Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register. JAMA Dermatology, 157(1), 66-73. https://doi.org/10.1001/jamadermatol.2020.4202

Importance: Treatments for psoriasis may be less effective in everyday practice than in clinical trials. Emulating a target trial using data from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) can provide t... Read More about Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register..

Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry. (2020)
Journal Article
Lambie. (2020). Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry. Clinical Kidney Journal, 1003 - 1011. https://doi.org/10.1093/ckj/sfaa051

Background: There is limited information available on the use of assisted peritoneal dialysis (PD) over time and the impact of economic incentives on its utilization. The aim of this study was to describe the trends in assisted PD utilization and the... Read More about Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry..

The prognostic value of Tei index in acute myocardial infarction: a systematic review (2020)
Journal Article
(2020). The prognostic value of Tei index in acute myocardial infarction: a systematic review. Echo Research and Practice, 49 - 58. https://doi.org/10.1530/ERP-20-0017

Background: Echocardiographic evaluation of left ventricular ejection fraction (LVEF) is used in the risk stratification of patients with an acute myocardial infarction (AMI). However, the prognostic value of the Tei index, an alternative measure of... Read More about The prognostic value of Tei index in acute myocardial infarction: a systematic review.

Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis. (2020)
Journal Article
(2020). Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis. Health Technology Assessment, 1 - 252. https://doi.org/10.3310/hta24720

BACKGROUND: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk is needed to plan management. OBJECTIVES: To assess the performance of existing pre-eclampsia prediction models and... Read More about Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis..

Transoral Robotic Surgery for Residual and Recurrent Oropharyngeal Cancers (2020)
Journal Article
(2020). Transoral Robotic Surgery for Residual and Recurrent Oropharyngeal Cancers. Otolaryngologic Clinics of North America, 1091 -1108. https://doi.org/10.1016/j.otc.2020.07.016

Trans-oral robotic surgery (TORS) was approved by the FDA in 2009 and over the past decade head and neck surgeons have adopted the technology for the benefit of their patients. Whilst the surgical methods have evolved, there has been little considera... Read More about Transoral Robotic Surgery for Residual and Recurrent Oropharyngeal Cancers.

Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. (2020)
Journal Article
Mamas. (2020). Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. Resuscitation, 166 - 173. https://doi.org/10.1016/j.resuscitation.2020.10.005

AIMS: The aim of this study is to analyse the causes of cardiac arrests (CA) in the emergency departments (ED) in the United States and their clinical outcomes according to whether they had a primary or a secondary diagnosis of CA. METHODS: Data from... Read More about Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample..

Race and racism: are we too comfortable with comfort? (2020)
Journal Article
Silverwood. (2020). Race and racism: are we too comfortable with comfort?. British Journal of General Practice Open (BJGP Open), https://doi.org/10.3399/BJGPO.2020.0143

After the murder of George Floyd and the Black Lives Matter protests, there has been a renewed appetite to tackle racism in all aspects of life. Within medicine and especially primary care, many people seem unclear about the racial disparities in hea... Read More about Race and racism: are we too comfortable with comfort?.