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Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation (2020)
Journal Article
Hodgkinson, T., Gilbert, H., Diwan, A., Hoyland, J., Richardson, S., & Pandya, T. (2020). Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation. International Journal of Molecular Sciences, 7143 - 7143. https://doi.org/10.3390/ijms21197143

<jats:p>Growth differentiation factor (GDF) family members have been implicated in the development and maintenance of healthy nucleus pulposus (NP) tissue, making them promising therapeutic candidates for treatment of intervertebral disc (IVD) degene... Read More about Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation.

Epidemiology and Clinical Outcomes of Patients With Inflammatory Bowel Disease Presenting With Acute Coronary Syndrome (2020)
Journal Article
Mamas, Pemmasani, G., Elgendy, I., Leighton, J. A., Aronow, W. S., & Tremaine, W. J. (2021). Epidemiology and Clinical Outcomes of Patients With Inflammatory Bowel Disease Presenting With Acute Coronary Syndrome. Inflammatory Bowel Diseases, 27(7), 1017-1025. https://doi.org/10.1093/ibd/izaa237

BACKGROUND: Inflammatory bowel disease (IBD) is associated with an increased acute coronary syndrome (ACS) risk. Data are limited regarding the epidemiology and outcomes of ACS in patients with IBD. METHODS: A retrospective cohort analysis of patient... Read More about Epidemiology and Clinical Outcomes of Patients With Inflammatory Bowel Disease Presenting With Acute Coronary Syndrome.

Diffuse coronary artery vasospasm in a patient with subarachnoid hemorrhage: A case report (2020)
Journal Article
Mamas. (2020). Diffuse coronary artery vasospasm in a patient with subarachnoid hemorrhage: A case report. World Journal of Cardiology, 468 - 474. https://doi.org/10.4330/wjc.v12.i9.468

BACKGROUND Coronary artery vasospasm (CAV) is a reversible, transient form of vasoconstriction with clinical manifestations ranging from stable angina to acute coronary syndromes (ACS). Vasospasm of epicardial coronary arteries or associated micro-va... Read More about Diffuse coronary artery vasospasm in a patient with subarachnoid hemorrhage: A case report.

Diffuse coronary artery vasospasm in a patient with subarachnoid hemorrhage: A case report (2020)
Journal Article
Mamas. (2020). Diffuse coronary artery vasospasm in a patient with subarachnoid hemorrhage: A case report. World Journal of Cardiology, 468 - 474. https://doi.org/10.4330/wjc.v12.i9.468

BACKGROUND Coronary artery vasospasm (CAV) is a reversible, transient form of vasoconstriction with clinical manifestations ranging from stable angina to acute coronary syndromes (ACS). Vasospasm of epicardial coronary arteries or associated micro-va... Read More about Diffuse coronary artery vasospasm in a patient with subarachnoid hemorrhage: A case report.

German translation, cross-cultural adaptation and validation of the Musculoskeletal Health Questionnaire: cohort study. (2020)
Journal Article
KARSTENS, S., CHRISTIANSEN, D. H., BRINKMANN, M., HAHM, M., McCRAY, G., HILL, J. C., & JOOS, S. (2020). German translation, cross-cultural adaptation and validation of the Musculoskeletal Health Questionnaire: cohort study. European Journal of Physical and Rehabilitation Medicine, 56(6), 771-779. https://doi.org/10.23736/S1973-9087.20.06054-2

BACKGROUND: The Musculoskeletal Health Questionnaire (MSK-HQ) was developed to measure the health status of patients with various musculoskeletal conditions across multiple settings including rehabilitation. AIM: Formal translation and cross-cultural... Read More about German translation, cross-cultural adaptation and validation of the Musculoskeletal Health Questionnaire: cohort study..

Quantitative examination of video-recorded NHS Health Checks: comparison of the use of QRISK2 versus JBS3 cardiovascular risk calculators (2020)
Journal Article
(2020). Quantitative examination of video-recorded NHS Health Checks: comparison of the use of QRISK2 versus JBS3 cardiovascular risk calculators. BMJ Open, e037790 - ?. https://doi.org/10.1136/bmjopen-2020-037790

OBJECTIVES: Quantitatively examine the content of National Health Service Health Check (NHSHC), patient-practitioner communication balance and differences when using QRISK2 versus JBS3 cardiovascular disease (CVD) risk calculators. DESIGN: RIsk COmmu... Read More about Quantitative examination of video-recorded NHS Health Checks: comparison of the use of QRISK2 versus JBS3 cardiovascular risk calculators.

Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes (2020)
Journal Article
Wu. (2020). Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes. Clinical Science, 134(18), 2435 - 2445. https://doi.org/10.1042/CS20200147

High-risk pregnancies, such as pregnancies with gestational diabetes mellitus (GDM), are becoming more common and as such, have become important public health issues worldwide. GDM increases the risks of macrosomia, premature infants, and preeclampsi... Read More about Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes.

Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature (2020)
Journal Article
Mallen. (2020). Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13725

Background: The 2019 coronavirus disease (COVID-19) has become a global pandemic and the published literature describing the virus has grown exponentially.
Methods: We conducted a systematic review of the literature to identify the symptoms, comorb... Read More about Clinical features and outcomes of adults with COVID-19: A systematic review and pooled analysis of the literature.

Temporal Trends and Outcomes in Utilization of Transcatheter and Surgical Aortic Valve Therapies in Aortic Valve Stenosis Patients with Heart Failure (2020)
Journal Article
Mamas. (2020). Temporal Trends and Outcomes in Utilization of Transcatheter and Surgical Aortic Valve Therapies in Aortic Valve Stenosis Patients with Heart Failure. International Journal of Clinical Practice, e13711 - ?. https://doi.org/10.1111/ijcp.13711

INTRODUCTIONS & AIMS: Heart failure (HF) is a common comorbidity in patients undergoing surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR). We sought to access the temporal trends and outcomes of TAVR or SAVR i... Read More about Temporal Trends and Outcomes in Utilization of Transcatheter and Surgical Aortic Valve Therapies in Aortic Valve Stenosis Patients with Heart Failure.

Excimer laser coronary atherectomy during complex PCI: An analysis of 1,471 laser cases from the British Cardiovascular Intervention Society database. (2020)
Journal Article
Protty, M. B., Hussain, H. I., Gallagher, S., Al-Raisi, S., Aldalati, O., Farooq, V., …Kinnaird, T. (2021). Excimer laser coronary atherectomy during complex PCI: An analysis of 1,471 laser cases from the British Cardiovascular Intervention Society database. Catheterization and Cardiovascular Interventions, 97(5), E653-E660. https://doi.org/10.1002/ccd.29251

INTRODUCTION: Excimer laser coronary atherectomy (ELCA) is a recognized adjunctive therapy utilized in the percutaneous management of complex coronary lesions. Studies examining its safety and utility have been limited by small sample sizes. Our stud... Read More about Excimer laser coronary atherectomy during complex PCI: An analysis of 1,471 laser cases from the British Cardiovascular Intervention Society database..

3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants (2020)
Journal Article
Luis, E., Pan, H., Pan, H. M., Bajpai, R., Bastola, A. K., Bastola, A., …Yeong, W. Y. (2020). 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants. Polymers, 12(9), Article 2136. https://doi.org/10.3390/polym12092136

Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and ar... Read More about 3D Printed Silicone Meniscus Implants: Influence of the 3D Printing Process on Properties of Silicone Implants.

Insights into back pain through linkage of digital patient generated data with electronic health records (2020)
Presentation / Conference
Martinez De Pinillos, A., Helliwell, T., Cooper, M., Mullane, M., Meleck, S., O'hanlon, S., …Dhanjal, J. (2020, September). Insights into back pain through linkage of digital patient generated data with electronic health records. Paper presented at 36th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, Virtual

Background: Back pain affects up to 80% of the population in industrialised countries and is the largest cause of disability in the UK. Physician and patient engagement are critical to ensure timely and multidisciplinary collection of back pain event... Read More about Insights into back pain through linkage of digital patient generated data with electronic health records.

A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs (2020)
Journal Article
Pilkington, K., Ridge, D. T., Igwesi-Chidobe, C., Chew-Graham, C. A., Little, P., Babatunde, O., …Cheshire, A. (2020). A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs. Social Science and Medicine, 265, Article 113369. https://doi.org/10.1016/j.socscimed.2020.113369

Chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) is indicated by prolonged, medically unexplained fatigue (amongst other symptoms), not alleviated by rest, and causing substantial disability. There are limited treatments on offer, which... Read More about A relational analysis of an invisible illness: A meta-ethnography of people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their support needs.

Acceptability of Physician Associate Interns in Primary Care: Results from a Service Evaluation (2020)
Journal Article
Silverwood, & Lawton. (2020). Acceptability of Physician Associate Interns in Primary Care: Results from a Service Evaluation. BMC Family Practice, https://doi.org/10.21203/rs.3.rs-70741/v1

Abstract Background: Physician associates (PA) form part of the policy-driven response to increased primary care demand and a general practitioner recruitment and retention crisis. However, they are novel to the primary care workforce, have limitatio... Read More about Acceptability of Physician Associate Interns in Primary Care: Results from a Service Evaluation.

A Novel Primary Healthcare Physician Associate Internship: Results from a Service Evaluation (2020)
Journal Article
Silverwood, & Lawton. (2020). A Novel Primary Healthcare Physician Associate Internship: Results from a Service Evaluation. BMC Family Practice, https://doi.org/10.21203/rs.3.rs-70742/v1

Abstract Background: Physician associates (PA) are dependent healthcare professionals with two-years post-graduate generalist medical education. PAs can work in primary care immediately after graduation. However, PAs are novel to, and still relativel... Read More about A Novel Primary Healthcare Physician Associate Internship: Results from a Service Evaluation.

Nicotinamide restricts neural precursor proliferation to enhance catecholaminergic neuronal subtype differentiation from mouse embryonic stem cells (2020)
Journal Article
(2020). Nicotinamide restricts neural precursor proliferation to enhance catecholaminergic neuronal subtype differentiation from mouse embryonic stem cells. PloS one, https://doi.org/10.1371/journal.pone.0233477

<jats:title>Abstract</jats:title><jats:p>Emerging evidence indicates that a strong relationship exists between brain regenerative therapies and nutrition. Early life nutrition plays an important role during embryonic brain development, and there are... Read More about Nicotinamide restricts neural precursor proliferation to enhance catecholaminergic neuronal subtype differentiation from mouse embryonic stem cells.

SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study (2020)
Journal Article
Shields, A., Faustini, S. E., Perez-Toledo, M., Jossi, S., Aldera, E., Allen, J. D., …Richter, A. G. (2020). SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study. Thorax, 75(12), 1089 - 1094. https://doi.org/10.1136/thoraxjnl-2020-215414

<jats:sec><jats:title>Objective</jats:title><jats:p>To determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>A cross-s... Read More about SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study.