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All Outputs (5)

A urinary proteomics investigation of pregnancy-related complications (2019)
Thesis
Al-Jasim, W. F. (2019). A urinary proteomics investigation of pregnancy-related complications. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414917

Pre-eclampsia (PE) and intrauterine growth restriction (IUGR) are common disorders associated with placental implantation abnormalities in early pregnancy. Both conditions are heterogeneous, having complex and multiple aetiologies. PE complicates 5-8... Read More about A urinary proteomics investigation of pregnancy-related complications.

A pilot study to identify serum biomarkers for post-stroke spasticity and related skeletal muscle changes (2019)
Thesis
Wasif, A. M. (2019). A pilot study to identify serum biomarkers for post-stroke spasticity and related skeletal muscle changes. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414326

Spasticity is a common sensory-motor dysfunction observed following a stroke, and it is one of the signs indicating damage to the upper motor neurone system at the spinal or cerebral level. Stroke survivors often experience Some resistance to passive... Read More about A pilot study to identify serum biomarkers for post-stroke spasticity and related skeletal muscle changes.

Engineering and optimising a functional in vitro model of basal ganglia circuitry (2019)
Thesis
Kӧse-Dunn, M. J. (2019). Engineering and optimising a functional in vitro model of basal ganglia circuitry. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413812

The majority of neurological diseases (such as Parkinson’s and Huntington’s diseases) are progressive, debilitating and currently incurable. In an ageing population, the prevalence of such diseases will only increase over time, creating a need for be... Read More about Engineering and optimising a functional in vitro model of basal ganglia circuitry.

Design and fabrication of hydrogel scaffolds for osteochondral tissue regeneration (2019)
Thesis
Younus, Z. M. (2019). Design and fabrication of hydrogel scaffolds for osteochondral tissue regeneration. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413770

Osteochondral defects are serious clinical problems relating to damaged articular cartilage within joints, usually resulting from acute traumatic injury or an underlying bone disorder. A variety of therapeutic options have been investigated, with sev... Read More about Design and fabrication of hydrogel scaffolds for osteochondral tissue regeneration.

Application of data science to inform surface engineering for in vitro neural stem cell control (2018)
Thesis
Joseph, G. (2018). Application of data science to inform surface engineering for in vitro neural stem cell control. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/412289

The interest in the clinical use of stem cell therapies is increasing rapidly, with a need for more control over cell populations cultured/expanded in vitro. This is particularly relevant for the treatment of neurological disorders such as Parkinson'... Read More about Application of data science to inform surface engineering for in vitro neural stem cell control.