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Cognitive therapy for depression in tuberculosis treatment: protocol for multicentre pragmatic parallel arm randomised control trial with an internal pilot. (2024)
Journal Article
Fonseka, N., Khan, Z., Lewis, M., Kibria, Z., Ahmad, F., Khan, M. F., …Farooq, S. (2024). Cognitive therapy for depression in tuberculosis treatment: protocol for multicentre pragmatic parallel arm randomised control trial with an internal pilot. BMJ Open, 14(6), Article e083483. https://doi.org/10.1136/bmjopen-2023-083483

Introduction and objectivesThere is an unmet need to develop high-quality evidence addressing tuberculosis (TB)-related mental health comorbidity, particularly in the context of lower-middle-income countries. This study aims to examine the effectiven... Read More about Cognitive therapy for depression in tuberculosis treatment: protocol for multicentre pragmatic parallel arm randomised control trial with an internal pilot..

Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review (2024)
Journal Article
Farooq, S., Fonseka, N., Wajid Ali, M., Milner, A., Hamid, S., Sheikh, S., …Ayub, M. (2024). Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review. Schizophrenia Bulletin, Article sbae025. https://doi.org/10.1093/schbul/sbae025

Background and Hypothesis People with first-episode psychosis (FEP) in low- and lower-middle-income countries (LMIC) experience delays in receiving treatment, resulting in poorer outcomes and higher mortality. There is robust evidence for effective a... Read More about Early Intervention in Psychosis and Management of First Episode Psychosis in Low- and Lower-Middle-Income Countries: A Systematic Review.

The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol (2023)
Journal Article
Cox, N., Hawarden, A., Bajpai, R., Farooq, S., Twohig, H., Muller, S., & Scott, I. C. (2024). The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol. Rheumatology International, 44, 435–440. https://doi.org/10.1007/s00296-023-05450-y

Pain is a major challenge for patients with inflammatory arthritis (IA). Depression and anxiety are common comorbidities in IA, associating with worse outcomes. How they relate to pain is uncertain, with existing systematic reviews (a) mainly conside... Read More about The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol.

The acceptability of the Fire and Rescue Service working with primary care to improve identification of mental health problems in older adults. A mixed-method qualitative study (2023)
Journal Article
Fisher, T., Chew-Graham, C. A., Corp, N., Farooq, S., Kingston, P., Read, I., …Kingstone, T. (2023). The acceptability of the Fire and Rescue Service working with primary care to improve identification of mental health problems in older adults. A mixed-method qualitative study. British Journal of General Practice Open (BJGP Open), 7(4), Article 0059. https://doi.org/10.3399/bjgpo.2023.0059

Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial (2023)
Journal Article
Farooq, S., Sheikh, S., Dikomitis, L., Haq, M. M. U., Khan, A. J., Sanauddin, N., …Lewis, M. (2023). Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open, 13(7), Article e072471. https://doi.org/10.1136/bmjopen-2023-072471

Objectives In low/middle-income countries (LMICs), more than half of patients with first-episode psychosis initially seek treatment from traditional and religious healers as their first care. This contributes to an excessively long duration of untrea... Read More about Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial.

Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial (2023)
Journal Article
Farooq, S., Sheikh, S., Dikomitis, L., Haq, M. M. U., Khan, A. J., Sanauddin, N., …Lewis, M. (2023). Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open, 13(7), e072471. https://doi.org/10.1136/bmjopen-2023-072471

Objectives: In low/middle-income countries (LMICs), more than half of patients with first-episode psychosis initially seek treatment from traditional and religious healers as their first care. This contributes to an excessively long duration of untre... Read More about Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial.

Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review (2023)
Journal Article
Khan, M. F., Ul-Haq, Z., Ul Haq, M. M., Afridi, A., & Farooq, S. (2023). Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review. Pakistan Journal of Medical Sciences, 39(4), https://doi.org/10.12669/pjms.39.4.7286

Many people with Schizophrenia lack the resources and access to mental health services especially in low and middle income countries. Integration of mental health into primary care services can be a cost effective way of reducing the disability assoc... Read More about Role of Primary Care Physicians in management of Schizophrenia in Low and Middle Income Countries (LMIC): A systematic review.

Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan. (2023)
Journal Article
Valkovskaya, M., Hassan, A., Zartaloudi, E., Hussain, F., Umar, M., Khizar, B., …Kuchenbaecker, K. (2023). Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan. Psychiatric Genetics, 33(2), 69-78. https://doi.org/10.1097/ypg.0000000000000333

INTRODUCTION: Globally, 80% of the burdenof major depressive disorder (MDD) pertains to low- and middle-income countries. Research into genetic and environmental risk factors has the potential to uncover disease mechanisms that may contribute to bett... Read More about Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan..

Patients’ and healthcare professionals’ perspectives on a community-based intervention for schizophrenia in Pakistan: A focus group study (2022)
Journal Article
Ishaq Khattak, M., Dikomitis, L., Firaz Khan, M., Ul Haq, M., Saeed, U., Riaz Awan, N., …Farooq, S. (2022). Patients’ and healthcare professionals’ perspectives on a community-based intervention for schizophrenia in Pakistan: A focus group study. PloS one, https://doi.org/10.1371/journal.pone.0273286

OBJECTIVE: To explore the perceptions and experiences of schizophrenia from patients, their care givers, health care providers, spiritual and traditional healers to develop a community-based intervention for improving treatment adherence for people w... Read More about Patients’ and healthcare professionals’ perspectives on a community-based intervention for schizophrenia in Pakistan: A focus group study.

Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia (2022)
Journal Article
Farooq, S., Hattle, M., Dazzan, P., Kingstone, T., Ajnakina, O., Shiers, D., …Van Der Windt, D. (in press). Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia. BMJ Open, 12(4), https://doi.org/10.1136/bmjopen-2021-056420

ABSTRACTIntroductionTreatment Resistant Schizophrenia (TRS) is associated with significant impairment of functioning and high treatment costs. Identification of patients at high risk of TRS at their initial diagnosis may significantly improve clinica... Read More about Study protocol for the development and internal validation of SPIRIT (Schizophrenia Prediction of Resistance to Treatment): A clinical tool for predicting risk of treatment resistance to anti-psychotics in First Episode Schizophrenia.

An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels (2021)
Journal Article
de Leon, J., Schoretsanitis, G., Smith, R. L., Molden, E., Solismaa, A., Seppälä, N., …Marder, S. R. (2021). An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels. Pharmacopsychiatry, 55(02), 73-86. https://doi.org/10.1055/a-1625-6388

This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that clozapine is the third most toxic drug in the United States (US), and... Read More about An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels.

Suicide, self-harm and suicidal ideation during COVID-19: A systematic review (2021)
Journal Article
Farooq, S., Tunmore, J., Ali, W., & Ayub, M. (2021). Suicide, self-harm and suicidal ideation during COVID-19: A systematic review. Psychiatry Research, 306, Article ARTN 114228. https://doi.org/10.1016/j.psychres.2021.114228

We aimed to do a systematic review and meta-analysis of studies describing suicidal ideation, suicide attempts and suicide and associated risk factors during COVID-19 pandemic. We searched following electronic databases using relevant search terms: M... Read More about Suicide, self-harm and suicidal ideation during COVID-19: A systematic review.

The haematological side effects of clozapine: literature review and meta-analysis (2021)
Journal Article
Munshi, T., Naeem, F., Ayub, M., Farooq, S., Khachatryan, D., Asmer, S., …Fairbairn, J. (2021). The haematological side effects of clozapine: literature review and meta-analysis. BJPsych Open, 7(S1), https://doi.org/10.1192/bjo.2021.729

Aims This review and meta-analysis aim to estimate the cumulative incidence of clozapine induced agranulocytosis and leukopenia the impact of the associated factors such as dose of clozapine, duration of follow-up, gender and race on the cumulative... Read More about The haematological side effects of clozapine: literature review and meta-analysis.

Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data (2021)
Journal Article
Farooq. (2021). Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data. BMJ Open, 1-9. https://doi.org/10.1136/bmjopen-2020-042331

Introduction Individuals with schizophrenia are at a high risk of physical health comorbidities and premature mortality. Cardiovascular and metabolic causes are an important contributor. There are gaps in monitoring, documenting and managing these ph... Read More about Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data.

Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives (2021)
Journal Article
Nash, A., Kingstone, T., Farooq, S., Tunmore, J., & Chew-Graham, C. A. (2021). Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives. BMJ Open, e042497 - ?. https://doi.org/10.1136/bmjopen-2020-042497

OBJECTIVES: The side effects of antipsychotic medications (APs) can increase the risk of developing physical health conditions. Some APs pose a higher risk than others. Evidence suggests switching to lower risk APs can support physical health outcome... Read More about Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives.

Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes (2020)
Journal Article
Mohamed, M., Rashid, M., Farooq, S., Siddiqui, N., Parwani, P., Shiers, D., …Mamas, M. (2020). Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes. European Heart Journal, 41(Supplement_2), https://doi.org/10.1093/ehjci/ehaa946.3146

Background Severe mental illness (SMI) is associated with an increased risk of cardiovascular disease and mortality. However, it is unclear whether SMI patients are just as likely to receive guideline-recommended therapy for AMI as those without men... Read More about Acute myocardial infarction in several mental illness: a nationwide analysis of prevalence, management strategies and outcomes.

Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine (2020)
Journal Article
Farooq. (2020). Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine. https://doi.org/10.12669/pjms.36.7.3606

Background and Objectives: Stigma around COVID-19 is a major barrier in global efforts to control the COVID 19 pandemic. Limited data is available regarding stigma faced by COVID-19 patients in low- and middle-income countries (LMIC).... Read More about Scarlett Letter: A study based on experience of stigma by COVID-19 patients in quarantine.

Culturally adapted trauma-focused CBT-based guided self-help (CatCBT GSH) for female victims of domestic violence in Pakistan: feasibility randomized controlled trial. (2020)
Journal Article
Farooq. (2020). Culturally adapted trauma-focused CBT-based guided self-help (CatCBT GSH) for female victims of domestic violence in Pakistan: feasibility randomized controlled trial. Behavioural and Cognitive Psychotherapy, 50-61. https://doi.org/10.1017/S1352465820000685

BACKGROUND: Cognitive behaviour therapy (CBT), self-help and guided self-help interventions have been found to be efficacious and cost effective for victims of trauma, but there are limited data from low- and middle-income countries on culturally ada... Read More about Culturally adapted trauma-focused CBT-based guided self-help (CatCBT GSH) for female victims of domestic violence in Pakistan: feasibility randomized controlled trial..

Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial. (2020)
Journal Article
Farooq. (2020). Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial. British Journal of Psychiatry, 623-629. https://doi.org/10.1192/bjp.2020.138

BACKGROUND: With the development of evidence-based interventions for treatment of priority mental health conditions in humanitarian settings, it is important to establish the cost-effectiveness of such interventions to enable their scale-up. AIMS: To... Read More about Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial..

Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan (2020)
Journal Article
Shepherd, T. A., Ul-Haq, Z., Ul-Haq, M., Firaz Khan, M., Afridi, A., Dikomitis, L., …Farooq, S. (2020). Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan. BMJ Open, 10(6), https://doi.org/10.1136/bmjopen-2019-034709

Introduction: There is a significant treatment gap, with only a few community-based services for people with schizophrenia in Low- and Middle-Income countries. Poor treatment adherence in schizophrenia is associated with poorer health outcomes, suici... Read More about Supervised treatment in outpatients for schizophrenia plus (STOPS+): protocol for a cluster randomised trial of a community-based intervention to improve treatment adherence and reduce the treatment gap for schizophrenia in Pakistan.

Pharmacological interventions for prevention of depression in high risk conditions: Systematic review and meta-analysis. (2020)
Journal Article
Farooq. (2020). Pharmacological interventions for prevention of depression in high risk conditions: Systematic review and meta-analysis. Journal of Affective Disorders, 58 - 69. https://doi.org/10.1016/j.jad.2020.03.024

BACKGROUND: Background Depressive disorders account for almost half of all Disability Adjusted Life Years caused by psychiatric disorders but efficacy of pharmacological interventions to prevent depressive disorders is not known. We aimed to assess e... Read More about Pharmacological interventions for prevention of depression in high risk conditions: Systematic review and meta-analysis..

Do Asian Patients Require Only Half of the Clozapine Dose Prescribed for Caucasians? A Critical Overview (2020)
Journal Article
Farooq. (2020). Do Asian Patients Require Only Half of the Clozapine Dose Prescribed for Caucasians? A Critical Overview. Indian Journal of Psychological Medicine, 4-10. https://doi.org/10.4103/IJPSYM.IJPSYM_379_19

Since 1997, studies have found that Asians need lower clozapine doses than Caucasians. Caucasians with average clozapine metabolism may need from 300 to 600 mg/day to reach the therapeutic range (350 ng/ml). Thus, serum clozapine concentration-to-dos... Read More about Do Asian Patients Require Only Half of the Clozapine Dose Prescribed for Caucasians? A Critical Overview.

Hospital preparedness for disaster and mass casualty management in Pakistan: A cross-sectional evaluation study (2019)
Journal Article
Ul-Haq, Z., Hussain Shah, B., Ishaq Khattak, M., Fazid, S., Basharat, S., Hayat Khan, S., …Huda, Q. (2019). Hospital preparedness for disaster and mass casualty management in Pakistan: A cross-sectional evaluation study. American Journal of Disaster Medicine, 14(3), https://doi.org/10.5055/ajdm.2019.0330

Background: World Health Organization has advocated preemptive readiness of health systems to manage disastrous events. Pakistan is known to be highly susceptible to disasters on the one hand and significantly lacking in coping ability on the other.... Read More about Hospital preparedness for disaster and mass casualty management in Pakistan: A cross-sectional evaluation study.

Patterns of symptoms before a diagnosis of first episode psychosis: a latent class analysis of UK primary care electronic health records. (2019)
Journal Article
Chen, Y., Farooq, S., Edwards, J., Chew-Graham, C. A., Shiers, D., Frisher, M., …Jordan, K. P. (2019). Patterns of symptoms before a diagnosis of first episode psychosis: a latent class analysis of UK primary care electronic health records. BMC Medicine, 17, Article 227. https://doi.org/10.1186/s12916-019-1462-y

Background: The nature of symptoms in the prodromal period of first episode psychosis (FEP) remains unclear. The objective was to determine patterns of symptoms recorded in primary care in the 5-years before FEP diagnosis. Methods: The study was s... Read More about Patterns of symptoms before a diagnosis of first episode psychosis: a latent class analysis of UK primary care electronic health records..

Pharmacoepidemiology Research: delivering evidence about drug safety and effectiveness in mental health (2019)
Journal Article
Farooq. (2019). Pharmacoepidemiology Research: delivering evidence about drug safety and effectiveness in mental health. The Lancet Psychiatry, 363-370. https://doi.org/10.1016/S2215-0366%2819%2930298-6

There is a need for research that provides an evidence base for the pharmacotherapy of people with mental disorders. The abundance of digital data in recent years has facilitated pharmacoepidemiology in the form of observational comparative effective... Read More about Pharmacoepidemiology Research: delivering evidence about drug safety and effectiveness in mental health.

Video intervention for the psychiatric waiting room: proof-of-concept randomised controlled trial of RESOLVE (Relaxation Exercise, SOLVing problem and cognitive Errors). (2019)
Journal Article
Naeem, F., Munshi, T., Gratzer, D., Rodie, D., Irfan, M., Rao, S., …Lecomte, T. (2019). Video intervention for the psychiatric waiting room: proof-of-concept randomised controlled trial of RESOLVE (Relaxation Exercise, SOLVing problem and cognitive Errors). BJPsych Open, e77. https://doi.org/10.1192/bjo.2019.59

BACKGROUND: The waiting room in psychiatric services can provide an ideal setting for offering evidence-based psychological interventions that can be delivered through electronic media. Currently, there is no intervention available that have been d... Read More about Video intervention for the psychiatric waiting room: proof-of-concept randomised controlled trial of RESOLVE (Relaxation Exercise, SOLVing problem and cognitive Errors)..

Sharing information about diagnosis and outcome of firstepisode psychosis in patients presenting to early intervention services (2019)
Journal Article
Farooq. (2019). Sharing information about diagnosis and outcome of firstepisode psychosis in patients presenting to early intervention services. Early Intervention in Psychiatry, 657-666. https://doi.org/10.1111/eip.12670

Aim First-episode psychosis (FEP) can be a serious and debilitating disease, but there is limited literature on how to inform patients and carers about its diagnosis and outcome. We aimed to examine the attitudes, practices and views of clinicians w... Read More about Sharing information about diagnosis and outcome of firstepisode psychosis in patients presenting to early intervention services.

The reliability and clinical utility of ICD-11 schizoaffective disorder: A field trial. (2019)
Journal Article
Farooq. (2019). The reliability and clinical utility of ICD-11 schizoaffective disorder: A field trial. Schizophrenia Research, 235-241. https://doi.org/10.1016/j.schres.2019.02.011

A major goal for the revision of the International Classification of Diseases and Related Health Problems, Tenth Edition (ICD-10) is to increase the clinical utility of the diagnostic system. Schizoaffective disorder has a history of poor diagnostic... Read More about The reliability and clinical utility of ICD-11 schizoaffective disorder: A field trial..

Barriers to using clozapine in treatment-resistant schizophrenia: systematic review (2019)
Journal Article
Farooq. (2019). Barriers to using clozapine in treatment-resistant schizophrenia: systematic review. BJPsych Bulletin, 8-16. https://doi.org/10.1192/bjb.2018.67

Aims and method To systematically review the literature on barriers to the use of clozapine and identify any interventions for optimizing clozapine use in treatment-resistant schizophrenia. Journal databases were searched from 1972 to March 2018. Th... Read More about Barriers to using clozapine in treatment-resistant schizophrenia: systematic review.

Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. (2018)
Journal Article
Choudry, A., & Farooq, S. (2018). Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. BJPsych Bulletin, 345 - 352. https://doi.org/10.1192/pb.bp.116.055269

Aims and method To review the literature to examine the factors that may be affecting recruitment into psychiatry in the UK. We systematically searched four databases to identify studies from 1974 to 2016 and identified 27 papers that met the specifi... Read More about Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views..

Different communication strategies for disclosing a diagnosis of schizophrenia and related disorders. (2017)
Journal Article
Farooq, S., Johal, R. K., Ziff, C., & Naeem, F. (2017). Different communication strategies for disclosing a diagnosis of schizophrenia and related disorders. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD011707.pub2

BACKGROUND: Delivering the diagnosis of a serious illness is an important skill in most fields of medicine, including mental health. Research has found that communication skills can impact on a person's recall and understanding of the diagnosis, trea... Read More about Different communication strategies for disclosing a diagnosis of schizophrenia and related disorders..

mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review (2017)
Journal Article
Gire, N., Farooq, S., Naeem, F., Duxbury, J., McKeown, M., Kundi, P. S., …Husain, N. mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review. mHealth, 3, 33-33. https://doi.org/10.21037/mhealth.2017.07.03

The relative burden of mental health disorders is increasing globally, in terms of prevalence and disability. There is limited data available to guide treatment choices for clinicians in low resourced settings, with mHealth technologies being a poten... Read More about mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review.

Explanatory model of illness of the patients with schizophrenia and the role of educational intervention (2017)
Journal Article
Farooq. (2017). Explanatory model of illness of the patients with schizophrenia and the role of educational intervention. Schizophrenia Research, 68-73. https://doi.org/10.1016/j.schres.2017.03.006

This randomized controlled trial was conducted at Department of Psychiatry, Lady Reading Hospital, Peshawar from February to August 2015 to explore beliefs and concepts of patients with schizophrenia about their illness and to find out the effectiven... Read More about Explanatory model of illness of the patients with schizophrenia and the role of educational intervention.

Adherence to medication in the community: audit cycle of interventions to improve the assessment of adherence (2017)
Journal Article
Farooq, S., & Choudry, A. (2017). Adherence to medication in the community: audit cycle of interventions to improve the assessment of adherence. BJPsych Bulletin, 41 - 44. https://doi.org/10.1192/pb.bp.115.053520

Aims and method To investigate whether medication adherence is monitored during follow-up in out-patient reviews. A retrospective audit was carried out with a sample of 50 follow-up patients with a diagnosis of schizophrenia or schizoaffective disord... Read More about Adherence to medication in the community: audit cycle of interventions to improve the assessment of adherence.

A survey of eMedia-delivered interventions for schizophrenia used in randomized controlled trials (2017)
Journal Article
Farooq. (2017). A survey of eMedia-delivered interventions for schizophrenia used in randomized controlled trials. Neuropsychiatric Disease and Treatment, 233 -243. https://doi.org/10.2147/ndt.s115897

Background: Randomized trials evaluating electronic Media (eMedia) delivery of interventions are increasingly frequent in mental health. Although a number of reviews have reported efficacy of these interventions, none has reviewed the type of eMedia... Read More about A survey of eMedia-delivered interventions for schizophrenia used in randomized controlled trials.

Prescribing pattern of clozapine and other antipsychotics for patients with first-episode psychosis: a cross-sectional survey of early intervention teams (2016)
Journal Article
Tungaraza, T. E., Ahmed, W., Chira, C., Turner, E., Mayaki, S., Nandhra, H. S., …Farooq, S. (2017). Prescribing pattern of clozapine and other antipsychotics for patients with first-episode psychosis: a cross-sectional survey of early intervention teams. Therapeutic Advances in Psychopharmacology, 7(3), 103-111. https://doi.org/10.1177/2045125316683151

Objective: To describe the pattern of antipsychotic drug prescribing in patients with first episode psychosis, with more emphasis in the use of clozapine in this group of patients. Method: A cross-sectional survey involving six early intervention... Read More about Prescribing pattern of clozapine and other antipsychotics for patients with first-episode psychosis: a cross-sectional survey of early intervention teams.

TechCare: mobile assessment and therapy for psychosis - an intervention for clients in the Early Intervention Service: A feasibility study protocol (2016)
Journal Article
Farooq, S. (2016). TechCare: mobile assessment and therapy for psychosis - an intervention for clients in the Early Intervention Service: A feasibility study protocol. SAGE Open Medicine, 2050312116669613 - ?. https://doi.org/10.1177/2050312116669613

OBJECTIVES: Technological advances in healthcare have shown promise when delivering interventions for mental health problems such as psychosis. The aim of this project is to develop a mobile phone intervention for people with psychosis and to conduct... Read More about TechCare: mobile assessment and therapy for psychosis - an intervention for clients in the Early Intervention Service: A feasibility study protocol.

Effect of a Multicomponent Behavioral Intervention in Adults Impaired by Psychological Distress in a Conflict-Affected Area of Pakistan: A Randomized Clinical Trial (2016)
Journal Article
Rahman, A., Hamdani, S. U., Awan, N. R., Bryant, R. A., Dawson, K. S., Khan, M. F., …van Ommeren, M. (2016). Effect of a Multicomponent Behavioral Intervention in Adults Impaired by Psychological Distress in a Conflict-Affected Area of Pakistan: A Randomized Clinical Trial. Journal of the American Medical Association, 316(24), 2609-2607. https://doi.org/10.1001/jama.2016.17165

Importance The mental health consequences of conflict and violence are wide-ranging and pervasive. Scalable interventions to address a range of mental health problems are needed. Objective To test the effectiveness of a multicomponent behavioral... Read More about Effect of a Multicomponent Behavioral Intervention in Adults Impaired by Psychological Distress in a Conflict-Affected Area of Pakistan: A Randomized Clinical Trial.

Prevalence of nonaffective psychosis in intellectually disabled clients: systematic review and meta-analysis. (2016)
Journal Article
Farooq, S. (2016). Prevalence of nonaffective psychosis in intellectually disabled clients: systematic review and meta-analysis. Psychiatric Genetics, 145 - 155. https://doi.org/10.1097/YPG.0000000000000137

Epidemiological studies report high rates of schizophrenia in individuals with intellectual disability (ID). However, this subject has not been reviewed systematically. We aim to review studies that report the prevalence of nonaffective psychosis in... Read More about Prevalence of nonaffective psychosis in intellectually disabled clients: systematic review and meta-analysis..

Reporting and understanding the safety and adverse effect profile of mobile apps for psychosocial interventions: An update (2016)
Journal Article
Farooq. (2016). Reporting and understanding the safety and adverse effect profile of mobile apps for psychosocial interventions: An update. World Journal of Psychiatry, 187 - 191. https://doi.org/10.5498/WJP.v6.i2.187

Recent years have seen a rapidly increasing trend towards the delivery of health technology through mobile devices. Smartphones and tablet devices are thus becoming increasingly popular for accessing information and a wide range of services, includin... Read More about Reporting and understanding the safety and adverse effect profile of mobile apps for psychosocial interventions: An update.

A global mental health fund for serious mental illness in low-income and middle-income countries. (2016)
Journal Article
Farooq. (2016). A global mental health fund for serious mental illness in low-income and middle-income countries. The Lancet Psychiatry, 495 - 497. https://doi.org/10.1016/S2215-0366%2816%2900105-X

Serious Mental Illnesses (SMI) are psychiatric disorders (excluding developmental and substance use disorders) that result in considerable functional impairment. These conditions receive little or no funding in most Low and Middle Income (LAMI) co... Read More about A global mental health fund for serious mental illness in low-income and middle-income countries..

Brief Cognitive Behavioral Therapy for Psychosis (CBTp) for Schizophrenia: Literature Review and Meta-analysis (2016)
Journal Article
Naeem, F., Khoury, B., Munshi, T., Ayub, M., Lecomte, T., Kingdon, D., & Farooq, S. (2016). Brief Cognitive Behavioral Therapy for Psychosis (CBTp) for Schizophrenia: Literature Review and Meta-analysis. International Journal of Cognitive Therapy, 9(1), 73-86. https://doi.org/10.1521/ijct_2016_09_04

There is a great deal of evidence supporting the use of CBT for psychosis (CBTp). In fact, CBTp is recommended by the National Treatment Guidelines in both the U.K. and the U.S. The availability of CBTp, however, remains an issue due to a variety of... Read More about Brief Cognitive Behavioral Therapy for Psychosis (CBTp) for Schizophrenia: Literature Review and Meta-analysis.

Telling the patients about diagnosis and outcome of schizophrenia: what, when and how? (2016)
Journal Article
Farooq, S., Naeem, F., & Singh, S. P. (2016). Telling the patients about diagnosis and outcome of schizophrenia: what, when and how?. Early Intervention in Psychiatry, 10(2), 101-102. https://doi.org/10.1111/eip.12310

Informing patients about the diagnosis and outcome of a serious disorder is a key clinical skill and a basic ethical duty in a therapeutic encounter. How clinicians meet this challenge in schizophrenia, which is arguably one of the most serious menta... Read More about Telling the patients about diagnosis and outcome of schizophrenia: what, when and how?.

Cognitive Behaviour Therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals: Results of a feasibility study (2016)
Journal Article
Farooq. (2016). Cognitive Behaviour Therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals: Results of a feasibility study. Schizophrenia Research, 69-74. https://doi.org/10.1016/j.schres.2016.03.003

Availability of Cognitive Behavior Therapy for psychosis (CBTp) is limited in spite of strong evidence base. The purpose of this study was to determine the feasibility of a CBTp based Guided Self-help (CBTp-GSH) in comparison to Treatment As Usual (T... Read More about Cognitive Behaviour Therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals: Results of a feasibility study.

Development of fixed dose combination tablets of aripiprazole plus divalproex sodium and their simultaneous determination using HPLC-UV (2016)
Journal Article
Ahmed, Z., Subhan, F., Ahmed, S., Abdur Rasheed, Q., Ahmed, S., Shahid, M., & Farooq, S. (2016). Development of fixed dose combination tablets of aripiprazole plus divalproex sodium and their simultaneous determination using HPLC-UV. Drug Development and Industrial Pharmacy, 42(9), 1393-1405. https://doi.org/10.3109/03639045.2015.1137305

A vast majority of psychiatric patients are effectively treated with combination of drugs to improve efficacy and adherence, but due to limited research and development in fixed dose combination (FDC) in psychiatry, these products are not commonly av... Read More about Development of fixed dose combination tablets of aripiprazole plus divalproex sodium and their simultaneous determination using HPLC-UV.

Development, Testing and Reporting of Mobile Apps for Psycho-social Interventions: Lessons from the Pharmaceuticals. (2015)
Journal Article
Farooq. (2015). Development, Testing and Reporting of Mobile Apps for Psycho-social Interventions: Lessons from the Pharmaceuticals. https://doi.org/10.4172/2168-9784.1000.191

The mobile Health offers great potential for delivery of Psycho-social Interventions. So far, the researchers have focused mainly on efficacy, and to some extent feasibility of Psycho-social Interventions. Poor reporting of development and initial te... Read More about Development, Testing and Reporting of Mobile Apps for Psycho-social Interventions: Lessons from the Pharmaceuticals..

Interventions for psychotic symptoms concomitant with epilepsy (2015)
Journal Article
Farooq, S., & Sherin, A. Interventions for psychotic symptoms concomitant with epilepsy. Cochrane Database of Systematic Reviews, 2020(4), https://doi.org/10.1002/14651858.cd006118.pub3

Background This is an updated version of the original Cochrane review published in Issue 4, 2008. People suffering from epilepsy have an increased risk of experiencing psychotic symptoms. The psychotic syndromes associated with epilepsy have gene... Read More about Interventions for psychotic symptoms concomitant with epilepsy.

Requirement of research as a learning tool in medical education - less is more (2015)
Journal Article
Farooq, S. (2015). Requirement of research as a learning tool in medical education - less is more. Journal of Postgraduate Medical Institute, 29(3),

The importance of research in providing evidence based solutions can't be overemphasized. Therefore almost all curricula both in under and postgraduate medical training have some components of training in research. This varies from teaching in statis... Read More about Requirement of research as a learning tool in medical education - less is more.

Pharmacological interventions for acute and transient psychotic disorder (ATPD) (2015)
Journal Article
Farooq, S., Rehman, M., & Naeem, F. Pharmacological interventions for acute and transient psychotic disorder (ATPD). Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd011974

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate the effects of pharmacological interventions, including cost‐effectiveness, when compared to placebo or between different pharmacological agents in... Read More about Pharmacological interventions for acute and transient psychotic disorder (ATPD).

Apps in mental health practice: uses, opportunities and challenges. (2015)
Journal Article
Farooq. (2015). Apps in mental health practice: uses, opportunities and challenges. BJPsych Bulletin, 288 - 290. https://doi.org/10.1192/pb.bp.114.050005

Smartphones are used by patients and clinicians alike. Vast numbers of software applications (apps) run on smartphones and carry out useful functions. Clinician- and patient-oriented mental health apps have been developed. In this article, we provide... Read More about Apps in mental health practice: uses, opportunities and challenges..

Problem Management Plus (PM+) for common mental disorders in a humanitarian setting in Pakistan; study protocol for a randomised controlled trial (RCT) (2015)
Journal Article
Sijbrandij, M., Farooq, S., Bryant, R. A., Dawson, K., Hamdani, S. U., Chiumento, A., …van Ommeren, M. (2015). Problem Management Plus (PM+) for common mental disorders in a humanitarian setting in Pakistan; study protocol for a randomised controlled trial (RCT). BMC Psychiatry, 15(1), Article 232. https://doi.org/10.1186/s12888-015-0602-y

Background In humanitarian settings common mental disorders (depression, anxiety disorders, posttraumatic stress disorder) are highly prevalent. The World Health Organization (WHO) has developed Problem Management Plus (PM+), a 5-session, individual... Read More about Problem Management Plus (PM+) for common mental disorders in a humanitarian setting in Pakistan; study protocol for a randomised controlled trial (RCT).

Schizophrenia diagnosis and treatment by general practitioners: A cross-sectional study in district Peshawar, Pakistan (2015)
Journal Article
Irfan, M., Miguel Caldas de Almeida, J., MP Irfan, U., Ahmad Raza, U., & Farooq, S. (2015). Schizophrenia diagnosis and treatment by general practitioners: A cross-sectional study in district Peshawar, Pakistan. Journal of the Pakistan Medical Association, 65(9), 937-942

Objective: To assess the knowledge and practices of general practitioners about diagnosis and treatment of schizophrenia and determine their association with clinical exposure to such cases in practice. Methods: The cross-sectional study was conduct... Read More about Schizophrenia diagnosis and treatment by general practitioners: A cross-sectional study in district Peshawar, Pakistan.

Acceptance and Commitment Therapy for schizophrenia and related disorders (2015)
Journal Article
Naeem, F., Asmer, M. S., Khoury, B., Kingdon, D., & Farooq, S. Acceptance and Commitment Therapy for schizophrenia and related disorders. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd011734

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To compare the efficacy of ACT for people with schizophrenia compared with (a) treatment as usual and (b) other psychosocial interventions.

Explanatory models of psychosis amongst British South Asians (2015)
Journal Article
Bhikha, A., Farooq, S., Chaudhry, N., Naeem, F., & Husain, N. (2015). Explanatory models of psychosis amongst British South Asians. Asian Journal of Psychiatry, 16, 48-54. https://doi.org/10.1016/j.ajp.2015.05.042

Purpose A strong interest in the understanding, exploring, and extracting explanatory models of psychosis has recently arisen. Explanatory models (EMs) offer justifications and propose explanations when coping with and treating illnesses. Therefore,... Read More about Explanatory models of psychosis amongst British South Asians.

Brief culturally adapted CBT for psychosis (CaCBTp): A randomized controlled trial from a low income country (2015)
Journal Article
Naeem, F., Saeed, S., Irfan, M., Kiran, T., Mehmood, N., Gul, M., …Kingdon, D. (2015). Brief culturally adapted CBT for psychosis (CaCBTp): A randomized controlled trial from a low income country. Schizophrenia Research, 164(1-3), 143-148. https://doi.org/10.1016/j.schres.2015.02.015

Evidence for the effectiveness of Culturally adapted CBT for psychosis in Low And Middle Income Countries (LAMIC) is limited. Therefore, brief Culturally adapted CBT for psychosis (CaCBTp) targeted at symptoms of schizophrenia for outpatients plus tr... Read More about Brief culturally adapted CBT for psychosis (CaCBTp): A randomized controlled trial from a low income country.

Self-help and guided self-help interventions for schizophrenia and related disorders (2015)
Journal Article
Naeem, F., Xiang, S., Munshi, T. A., Kingdon, D., & Farooq, S. Self-help and guided self-help interventions for schizophrenia and related disorders. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd011698

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate evidence from randomised controlled trials (RCTs) for the efficacy of self‐help/guided self‐help for people with schizophrenia or related disorders... Read More about Self-help and guided self-help interventions for schizophrenia and related disorders.

Brief Culturally adapted CBT (CaCBT) for depression: A randomized controlled trial from Pakistan (2015)
Journal Article
Naeem, F., Gul, M., Irfan, M., Munshi, T., Asif, A., Rashid, S., …Ayub, M. (2015). Brief Culturally adapted CBT (CaCBT) for depression: A randomized controlled trial from Pakistan. Journal of Affective Disorders, 177, 101-107. https://doi.org/10.1016/j.jad.2015.02.012

Objectives To determine the efficacy of brief Culturally adapted CBT (CaCBT) for depression when added to Treatment As usual (TAU)—delivered by trained therapists using a manual compared with alone TAU. Methods This was an assessor-blinded, rand... Read More about Brief Culturally adapted CBT (CaCBT) for depression: A randomized controlled trial from Pakistan.

Interventions Following Traumatic Event in Children and Adolescents: An Evidence-Based Response (2015)
Journal Article
Farooq, S. (2015). Interventions Following Traumatic Event in Children and Adolescents: An Evidence-Based Response. https://doi.org/10.4172/Psychiatry.1000269

Introduction - Recent attack on the Army Public School in Peshawar, Pakistan, is perhaps one the worst act of terrorism committed involving children and adolescent. There have been numerous acts of school shootings reported from Western and Americ... Read More about Interventions Following Traumatic Event in Children and Adolescents: An Evidence-Based Response.

Working through interpreters in old age psychiatry: a literature review (2015)
Journal Article
Farooq, S., Kingston, P., & Regan, J. (2015). Working through interpreters in old age psychiatry: a literature review. Mental Health Review Journal, 20(1), 36-47. https://doi.org/10.1108/mhrj-12-2013-0040

Purpose The purpose of this paper is to systematically appraise the effect of use of interpreters for mental health problems in old age. The primary objective of the review is to assess the impact of a language barrier for assessment and management... Read More about Working through interpreters in old age psychiatry: a literature review.

Clozapine prescribing in the UK: views and experience of consultant psychiatrists (2015)
Journal Article
Tungaraza, T. E., & Farooq, S. (2015). Clozapine prescribing in the UK: views and experience of consultant psychiatrists. Therapeutic Advances in Psychopharmacology, 5(2), 88-96. https://doi.org/10.1177/2045125314566808

Objectives: It has been repeatedly shown that clozapine is underutilized and there is delayed use of it in clinical practice. Method: An online survey was sent to 2771 consultant psychiatrists registered with the Royal College of Psychiatrists in... Read More about Clozapine prescribing in the UK: views and experience of consultant psychiatrists.

A Qualitative Study to Explore Patients’, Carers’ and Health Professionals’ Views to Culturally Adapt CBT for Psychosis (CBTp) in Pakistan (2014)
Journal Article
Naeem, F., Habib, N., Gul, M., Khalid, M., Saeed, S., Farooq, S., …Kingdon, D. (2016). A Qualitative Study to Explore Patients’, Carers’ and Health Professionals’ Views to Culturally Adapt CBT for Psychosis (CBTp) in Pakistan. Behavioural and Cognitive Psychotherapy, 44(1), 43-55. https://doi.org/10.1017/s1352465814000332

Background: Cognitive Behaviour Therapy (CBT) has an established evidence base and is recommended by the national organizations in United Kingdom and the United States. CBT remains under utilized in low and middle income countries. CBT was developed... Read More about A Qualitative Study to Explore Patients’, Carers’ and Health Professionals’ Views to Culturally Adapt CBT for Psychosis (CBTp) in Pakistan.

Fixed dose-combination products in psychiatry: Systematic review and meta-analysis (2014)
Journal Article
Farooq, S., & Singh, S. P. (2015). Fixed dose-combination products in psychiatry: Systematic review and meta-analysis. Journal of Psychopharmacology, 29(5), 556-564. https://doi.org/10.1177/0269881114541016

Despite highly prevalent use of drug combinations in psychiatry, combination products are not commonly available. We aimed to systematically review the evidence for the use and efficacy of combination products in the practice of psychiatry. Systemati... Read More about Fixed dose-combination products in psychiatry: Systematic review and meta-analysis.

Cognitive Behavioral Therapy (Brief vs Standard Duration) for Schizophrenia (2014)
Journal Article
Naeem, F., Farooq, S., & Kingdon, D. (2014). Cognitive Behavioral Therapy (Brief vs Standard Duration) for Schizophrenia. Schizophrenia Bulletin, 40(5), 958-959. https://doi.org/10.1093/schbul/sbu113

There is some evidence from research that suggests that cognitive behavioral therapy for psychosis (CBTp) might offer some advantage if offered in combination with pharmacological treatments for people with schizophrenia. There are, however, limitati... Read More about Cognitive Behavioral Therapy (Brief vs Standard Duration) for Schizophrenia.

Tackling nonadherence in psychiatric disorders: current opinion (2014)
Journal Article
Farooq, S., & Naeem, F. (in press). Tackling nonadherence in psychiatric disorders: current opinion. Neuropsychiatric Disease and Treatment, 2014(10), 1069—1077. https://doi.org/10.2147/ndt.s40777

Abstract: Nonadherence to treatment is a major challenge in all fields of medicine, and it has been claimed that increasing the effectiveness of adherence interventions may have far greater impact on the health of the population than any improvement... Read More about Tackling nonadherence in psychiatric disorders: current opinion.

Effect of fasting on serum lithium levels: an experimental study in animal models. (2014)
Journal Article
Ahmed, Z., Subhan, F., Tahir Shah, M., & Farooq, S. (2014). Effect of fasting on serum lithium levels: an experimental study in animal models. Pakistan Journal of Pharmaceutical Sciences, 27(1), 33-37

Muslims throughout the world observe dawn to dusk fast in the month of Holy Ramadan. This study aims to investigate the effect of fasting on serum lithium levels in an animal model under typical conditions of Ramadan. Animals were categorized into or... Read More about Effect of fasting on serum lithium levels: an experimental study in animal models..

THE EARLY AND EFFECTIVE TREATMENT FOR SEVERE MENTAL ILLNESS (SMI) IN LOW AND MIDDLE INCOME (LAMI) COUNTRIES: A PUBLIC HEALTH CHALLENGE (2013)
Journal Article
Farooq, S. (in press). THE EARLY AND EFFECTIVE TREATMENT FOR SEVERE MENTAL ILLNESS (SMI) IN LOW AND MIDDLE INCOME (LAMI) COUNTRIES: A PUBLIC HEALTH CHALLENGE. Khyber Medical University Journal, 5(4), 177-178

The common mental disorders such as depression and anxiety are highly prevalent psychiatric disorders. Only one disorder i.e. depression is to become second leading cause of burden of disease in developing countries and it is appropriate that these d... Read More about THE EARLY AND EFFECTIVE TREATMENT FOR SEVERE MENTAL ILLNESS (SMI) IN LOW AND MIDDLE INCOME (LAMI) COUNTRIES: A PUBLIC HEALTH CHALLENGE.

Cognitive behaviour therapy (brief versus standard duration) for schizophrenia (2013)
Journal Article
Naeem, F., Farooq, S., & Kingdon, D. Cognitive behaviour therapy (brief versus standard duration) for schizophrenia. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd010646

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To compare the effects of brief cognitive behavioural therapy against standard cognitive behavioural therapy for schizophrenia.

Early intervention for psychosis in low- and middle-income countries needs a public health approach (2013)
Journal Article
Farooq, S. (2013). Early intervention for psychosis in low- and middle-income countries needs a public health approach. British Journal of Psychiatry, 202(3), 168-169. https://doi.org/10.1192/bjp.bp.112.113761

Early intervention in psychosis has significantly improved outcomes compared with standard treatment but it is considered as a luxury for low- and middle-income (LAMI) countries. However, a public health approach that is based on the principles of su... Read More about Early intervention for psychosis in low- and middle-income countries needs a public health approach.

Collaborative care for depression: a literature review and a model for implementation in developing countries (2013)
Journal Article
Farooq, S. (2013). Collaborative care for depression: a literature review and a model for implementation in developing countries. International Health, 5(1), 24-28. https://doi.org/10.1093/inthealth/ihs015

Depression will soon be the leading cause of disability in developing countries but effective treatments are not widely available. There is compelling evidence for the effectiveness and cost-effectiveness of the multicondition collaborative care (MCC... Read More about Collaborative care for depression: a literature review and a model for implementation in developing countries.