Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery
(2018)
Journal Article
Foley, D. W., Pathak, R. B., Phillips, T. R., Wilson, G. L., Bailey, P. D., Pieri, M., …Meredith, D. (2018). Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery. European Journal of Medicinal Chemistry, 156, 180-189. https://doi.org/10.1016/j.ejmech.2018.06.064
The broad substrate capacity of the intestinal oligopeptide transporter, PepT1, has made it a key target of research into drug delivery. Whilst the substrate capacity of this transporter is broad, studies have largely been limited to small peptides a... Read More about Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery.