A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome (2025)
Journal Article
Harrington, G. M. B., Cool, P., Hulme, C., Stokes-Fisher, J., Peffers, M., El Masri, W., …Wright, K. (2025). A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome. Journal of Neurotrauma, 42(3-4), https://doi.org/10.1101/2022.07.12.499696

Spinal cord injury (SCI) is a major cause of disability, with complications postinjury often leading to lifelong health issues with the need for extensive treatment. Neurological outcome post-SCI can be variable and difficult to predict, particularly... Read More about A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome.

A Rare Presentation of a Solitary Melanoma Bone Metastasis. (2022)
Journal Article
Cool. (2022). A Rare Presentation of a Solitary Melanoma Bone Metastasis. Cureus, e21479 - ?. https://doi.org/10.7759/cureus.21479

A 74-year-old woman presented with sudden onset pain and swelling in her right wrist. Plain radiographs showed a pathological fracture through a lytic lesion. The patient had a past medical history of melanoma on her right thigh, which had been excis... Read More about A Rare Presentation of a Solitary Melanoma Bone Metastasis..

Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations (2021)
Journal Article
Cool, Lyskjær, I., Davies, C., Strobl, A., Hindley, J., James, S., …Flanagan, A. M. (2021). Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations. Molecular Oncology, 15(12), 3679-3690. https://doi.org/10.1002/1878-0261.13102

Chondrosarcoma (CS) is a rare tumour type and the most common primary malignant bone cancer in adults. The prognosis, currently based on tumour grade, imaging and anatomical location, is not reliable and more objective biomarkers are required. We aim... Read More about Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations.

Routinely Measured Hematological Markers Can Help to Predict American Spinal Injury Association Impairment Scale Scores after Spinal Cord Injury (2020)
Journal Article
Harrington, G. M. B., Cool, P., Hulme, C., Osman, A., Roy Chowdhury, J., Kumar, N., …Wright, K. (2020). Routinely Measured Hematological Markers Can Help to Predict American Spinal Injury Association Impairment Scale Scores after Spinal Cord Injury. Journal of Neurotrauma, 38(3), https://doi.org/10.1089/neu.2020.7144

Neurological outcomes following spinal cord injury (SCI) are currently difficult to predict. Whilst the initial American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade can give an estimate of outcome, the high remaining degree of uncer... Read More about Routinely Measured Hematological Markers Can Help to Predict American Spinal Injury Association Impairment Scale Scores after Spinal Cord Injury.

Comorbidities and Pregnancy Do Not Affect Local Recurrence in Patients With Giant Cell Tumour of Bone (2020)
Journal Article
Howard, E. L., Gregory, J., Tsoi, K., Evans, S., Flanagan, A., & Cool, P. (2020). Comorbidities and Pregnancy Do Not Affect Local Recurrence in Patients With Giant Cell Tumour of Bone. Cureus, 12(7), Article e9164. https://doi.org/10.7759/cureus.9164

This study evaluates the relationship between pregnancy, comorbid conditions and giant cell tumour of bone. Furthermore, it examines if pregnancy and comorbid conditions affect the outcome following treatment for this tumour. A multi-centre retrospec... Read More about Comorbidities and Pregnancy Do Not Affect Local Recurrence in Patients With Giant Cell Tumour of Bone.

Radiological Features of Giant Cell Tumours of Bone (2020)
Journal Article
Howard, E. L., Gregory, J., Winn, N., Flanagan, A., & Cool, P. (2020). Radiological Features of Giant Cell Tumours of Bone. Cureus, 12(6), Article e8793. https://doi.org/10.7759/cureus.8793

Introduction The aim of this study was to evaluate radiological measurements to establish the origin of giant cell tumours of bone. Methods A multi-centre retrospective review was conducted of patients with histologically confirmed giant cell tumours... Read More about Radiological Features of Giant Cell Tumours of Bone.

Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI (2020)
Journal Article
Cool. (2020). Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI. Skeletal Radiology, 49, 869–881. https://doi.org/10.1007/s00256-019-03363-1

OBJECTIVE: To predict accurately whether a soft tissue mass was benign or malignant and to characterize its type using ultrasound, shear wave elastography and MRI. We hypothesized that with the addition of shear wave elastography, it would be possibl... Read More about Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI.