Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. (2025)
Journal Article
Williams, M. M., Smith, N. R., Uyl-de Groot, C. A., den Uil, C. A., Ross, J. S., Mohamed, M. O., …Cram, P. (in press). Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. Circulation: Cardiovascular Quality and Outcomes, Article e011636. https://doi.org/10.1161/CIRCOUTCOMES.124.011636

The authorization process and coverage/reimbursement mechanisms for medical devices play critical roles in device adoption and usage. However, international variation in these processes remains poorly characterized, especially with regard to data tra... Read More about Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries..

Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis. (2025)
Journal Article
Ibrahim, A., Shalabi, L., Zreigh, S., Ramadan, S., Mourad, S., Eljadid, G., …Mamas, M. (in press). Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis. Catheterization and Cardiovascular Interventions, 1-9. https://doi.org/10.1002/ccd.31461

Left atrial appendage occlusion (LAAO) is an alternative to chronic oral anticoagulation (OAT) for stroke prevention in nonvalvular atrial fibrillation (NVAF) patients with contraindications to OAT. Postprocedure antithrombotic therapy (ATT) is essen... Read More about Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis..

Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study (2025)
Journal Article
Dafaalla, M., Costa, F., Jia, H., Wijeysundera, H., Rashid, M., Graham, M. M., …Mamas, M. A. (in press). Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study. European Heart Journal Open, Article oeaf012. https://doi.org/10.1093/ehjopen/oeaf012

Background Treatment of patients with cancer presenting with ST-elevation myocardial infarction (STEMI) is complex given the increased risk of both thrombotic and major bleeding complications. Methods A nationally-linked cohort of STEMI patients betw... Read More about Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study.

Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective. (2025)
Journal Article
Doolub, G., Raichman, A., Abramov, D., Bang, V., Parwani, P., Karunanithi, K., …Mamas, M. A. (in press). Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective. Expert Review of Cardiovascular Therapy, 23(1-2), 35-43. https://doi.org/10.1080/14779072.2025.2463332

We present an analysis of cardiovascular-related deaths specific to hematological cancer patients in the United States from 1999 to 2020, examining trends in relation to age, gender, and type of hematological cancer. Utilizing the Multiple Cause of D... Read More about Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective..

Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society (2025)
Journal Article
Curzen, N., Routledge, H., McGrath, S., Abouelasaad, M., Mamas, M., Kinnaird, T., …Hildick-Smith, D. (in press). Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society. Interventional Cardiology: Reviews, Research, Resources, 20, https://doi.org/10.15420/icr.2024.43

Percutaneous techniques to treat obstructive coronary artery disease continue to evolve and the evidence base informing our practice is shared and summarised in international guidelines. In the UK, the British Cardiovascular Intervention Society repr... Read More about Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society.

Sex differences in patients with working diagnosis of myocardial infarction with nonobstructive coronary arteries (MINOCA) (2025)
Journal Article
Milewski, M., Desperak, A., Koźlik, M., Bujak, M., Gierlotka, M., Milewski, K., …Gasior, P. (in press). Sex differences in patients with working diagnosis of myocardial infarction with nonobstructive coronary arteries (MINOCA). Scientific Reports, 15(1), 1-11. https://doi.org/10.1038/s41598-025-87121-5

Myocardial infarction with nonobstructive coronary arteries (MINOCA) constitutes 3–15% of all acute myocardial infarctions. Women are more frequently diagnosed with MINOCA, although the influence of sex on long-term outcomes is still unclear. In this... Read More about Sex differences in patients with working diagnosis of myocardial infarction with nonobstructive coronary arteries (MINOCA).

Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization (2025)
Journal Article
Averbuch, T., Zafari, A., Islam, S., Lee, S. F., Sankaranarayanan, R., Greene, S. J., …Van Spall, H. G. (in press). Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization. ESC Heart Failure, 1-10. https://doi.org/10.1002/ehf2.15129

Aims: Risk prediction indices used in worsening heart failure (HF) vary in complexity, performance, and the type of datasets in which they were validated. We compared the performance of seven risk prediction indices in a contemporary cohort of patien... Read More about Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization.

The impact of specialist cardiology inpatient care on the long-term outcomes of non-ST-segment elevation myocardial infarction (NSTEMI): A nationwide cohort study. (2025)
Journal Article
Moledina, S. M., Weight, N., Cole, A., Rashid, M., Kontopantelis, E., & Mamas, M. A. (in press). The impact of specialist cardiology inpatient care on the long-term outcomes of non-ST-segment elevation myocardial infarction (NSTEMI): A nationwide cohort study. International Journal of Cardiology, 423, 1-10. https://doi.org/10.1016/j.ijcard.2025.132990

Specialist cardiac care has been shown to reduce inpatient mortality following non-ST segment myocardial infarction (NSTEMI), but whether this benefit extends beyond index admission is unclear. Using the linked Myocardial Ischaemia National Audit Pro... Read More about The impact of specialist cardiology inpatient care on the long-term outcomes of non-ST-segment elevation myocardial infarction (NSTEMI): A nationwide cohort study..

Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach. (2024)
Journal Article
Chew, N. W. S., Mehta, A., Goh, R. S. J., Zhang, A., Chen, Y., Chong, B., …Sperling, L. S. (2025). Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach. Circulation, 151(1), 98-119. https://doi.org/10.1161/CIRCULATIONAHA.124.070535

There is a new awareness of the widespread nature of metabolic dysfunction-associated steatotic liver disease (MASLD) and its connection to cardiovascular disease (CVD). This has catalyzed collaboration between cardiologists, hepatologists, endocrino... Read More about Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach..

Correction: Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. (2024)
Journal Article
Cole, A., Weight, N., Misra, S., Grapsa, J., Rutter, M. K., Siudak, Z., …Mamas, M. A. (in press). Correction: Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. Diabetologia, https://doi.org/10.1007/s00125-024-06337-8

Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data. (2024)
Journal Article
Cipolletta, E., Nakafero, G., McCormick, N., Yokose, C., Avery, A. J., Mamas, M. A., …Abhishek, A. (in press). Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data. The Lancet Rheumatology, 1-12. https://doi.org/10.1016/S2665-9913%2824%2900248-0

Initiating urate-lowering therapy can trigger gout flares. Gout flares have been associated with a temporally increased risk of cardiovascular events. Therefore, we aimed to estimate the risk of cardiovascular events in patients with gout initiating... Read More about Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data..

Intravascular Ultrasound‐Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review, Meta‐Analysis, and Meta‐Regression of Randomized Control Trials (2024)
Journal Article
Ahmed, M., Nadeem, Z. A., Ahsan, A., Javaid, H., Jain, H., Shahid, F., …Mamas, M. A. (in press). Intravascular Ultrasound‐Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review, Meta‐Analysis, and Meta‐Regression of Randomized Control Trials. Catheterization and Cardiovascular Interventions, 105(1), 68-271. https://doi.org/10.1002/ccd.31352

ABSTRACTBackgroundIntravascular ultrasound (IVUS) guidance during percutaneous coronary intervention (PCI) allows better assessment of coronary artery lesion characteristics than angiography alone. This systematic review and meta‐analysis aimed to co... Read More about Intravascular Ultrasound‐Guided Versus Angiography‐Guided Percutaneous Coronary Intervention: A Systematic Review, Meta‐Analysis, and Meta‐Regression of Randomized Control Trials.

Disparities in Peripheral Artery Disease-related Mortality in Chronic Inflammatory Disease in the United States from 1999 to 2020 (2024)
Journal Article
Olson, A., Pham, H. N., Ibrahim, R., Salih, M., Singh, A., & Mamas, M. A. (2024). Disparities in Peripheral Artery Disease-related Mortality in Chronic Inflammatory Disease in the United States from 1999 to 2020. Current Cardiology Reviews, 21, Article e1573403X353038. https://doi.org/10.2174/011573403x353038241125050631

Introduction: Peripheral arterial disease (PAD) is a marker of significant atherosclerotic cardiovascular disease and is associated with greater healthcare burden and worse prognosis in individuals with chronic inflammatory disease (CID). We aimed to... Read More about Disparities in Peripheral Artery Disease-related Mortality in Chronic Inflammatory Disease in the United States from 1999 to 2020.

Sex Differences in Patients Undergoing Left Main Stem Percutaneous Coronary Intervention for Stable Angina: Data From a National Registry. (2024)
Journal Article
Shamkhani, W., Zathar, Z., Khattak, S., Nolan, J., Chieffo, A., Kinnaird, T., & Mamas, M. A. (2024). Sex Differences in Patients Undergoing Left Main Stem Percutaneous Coronary Intervention for Stable Angina: Data From a National Registry. Journal of the American Heart Association, 13(22), Article e036569. https://doi.org/10.1161/JAHA.124.036569

Percutaneous coronary intervention (PCI) of the left main coronary artery (LMCA) for stable angina has steadily increased. Outcomes stratified by sex are inconclusive and limited. We assessed sex-based trends and differences in clinical outcomes amon... Read More about Sex Differences in Patients Undergoing Left Main Stem Percutaneous Coronary Intervention for Stable Angina: Data From a National Registry..

Abstract 4134687: Takotsubo Cardiomyopathy Complicating Stroke (2024)
Journal Article
Jang, S. H., Sposato, L., Choi, Y.-H., Geressu, A., Mamas, M., & Bagur, R. (2024). Abstract 4134687: Takotsubo Cardiomyopathy Complicating Stroke. Circulation, 150(Suppl_1), Article A4134687. https://doi.org/10.1161/circ.150.suppl_1.4134687

Background: There have been studies suggesting Takotsubo cardiomyopathy (TCM) as a potential complication following cerebrovascular accident (CVA), but the association, contributing factors, and prognosis significance have not been well-characterized... Read More about Abstract 4134687: Takotsubo Cardiomyopathy Complicating Stroke.

Correction to: same-day discharge after elective percutaneous coronary intervention for chronic total occlusion in the UK. (2024)
Journal Article
Taxiarchi, P., Kontopantelis, E., Kinnaird, T., Curzen, N., Ahmed, J., Zaman, A., …Mamas, M. A. (in press). Correction to: same-day discharge after elective percutaneous coronary intervention for chronic total occlusion in the UK. Journal of Invasive Cardiology, https://doi.org/10.25270/jic/21.00036.cx

This corrects the article doi: 10.25270/jic/21.00036.

Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study. (2024)
Journal Article
Istanbuly, S., Matetić, A., Bang, V., Sharma, K., Golwala, H., Kheiri, B., …Mamas, M. A. (2024). Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study. Croatian Medical Journal, 65(5), 405-416

To evaluate outcomes after percutaneous coronary intervention (PCI) in patients with cancer and atrial fibrillation (AF). Data of all adult discharges undergoing PCI between October 2015 and December 2018 were obtained from the National Inpatient Sam... Read More about Outcomes of 1.3 million patients undergoing percutaneous coronary intervention according to the presence of cancer and atrial fibrillation: a retrospective study..

TCT-59 Optimal Versus Sub-Optimal Intravascular Imaging-guided Percutaneous Coronary Intervention: A Meta-Analysis (2024)
Journal Article
Hamed, M., Elseidy, S., Ahmed, A., Gabr, E., Kahan, J., & Mamas, M. (2024). TCT-59 Optimal Versus Sub-Optimal Intravascular Imaging-guided Percutaneous Coronary Intervention: A Meta-Analysis. Journal of the American College of Cardiology, 84(18), B176. https://doi.org/10.1016/j.jacc.2024.09.606

Background
Intravascular imaging–guided percutaneous coronary intervention (PCI) has shown promising results. Our study aimed to compare the outcomes of optimal vs suboptimal intravascular imaging–guided PCI.

Ischemic and bleeding risk after ST-segment elevated myocardial infarction in patients with active cancer (2024)
Journal Article
Dafaalla, M., Costa, F., Jia, H., Wijeysundera, H., Rashid, M., Graham, M., …Mamas, M. (2024). Ischemic and bleeding risk after ST-segment elevated myocardial infarction in patients with active cancer. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.2633

Background Treatment of patients with cancer presenting with ST-elevation myocardial infarction (STEMI) is complex given the increased risk of both thrombotic and major bleeding complications. We evaluated the risk of major bleeding and re-infarction... Read More about Ischemic and bleeding risk after ST-segment elevated myocardial infarction in patients with active cancer.

Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD (2024)
Journal Article
Kobo, O., Kaur, G., Gulati, M., & Mamas, M. (2024). Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD. European Heart Journal, 45(Supplement_1), https://doi.org/10.1093/eurheartj/ehae666.3071

Background The American Heart Association’s Life’s Essential 8 (LE8) score is a helpful tool to quantify cardiovascular health (CVH) metrics. Sex differences in relation to LE8 and its association with mortality are not known. Methods The National He... Read More about Sex sifferences in lifes essential eight and its association with mortality among adults without known CVD.