Impact of education in patients undergoing physiotherapy for lower back pain: a level I systematic review and meta-analysis (2025)
Journal Article
Migliorini, F., Maffulli, N., Schäfer, L., Manocchio, N., Bossa, M., Foti, C., …Kubach, J. (in press). Impact of education in patients undergoing physiotherapy for lower back pain: a level I systematic review and meta-analysis. European Journal of Trauma and Emergency Surgery, 51(1), 1-19. https://doi.org/10.1007/s00068-025-02788-9

Introduction: Lower back pain (LBP) is one of the most common musculoskeletal disorders in modern society, with a lifetime incidence of up to 90%. According to most national and international guidelines, educational interventions play a central role... Read More about Impact of education in patients undergoing physiotherapy for lower back pain: a level I systematic review and meta-analysis.

Anterior Cruciate Ligament Reconstruction Using Lateral Extra-Articular Procedures: A Systematic Review (2025)
Journal Article
Migliorini, F., Lucenti, L., Mok, Y. R., Bardazzi, T., D’Ambrosi, R., De Carli, A., …Maffulli, N. (in press). Anterior Cruciate Ligament Reconstruction Using Lateral Extra-Articular Procedures: A Systematic Review. Medicina, 61(2), 1-18. https://doi.org/10.3390/medicina61020294

Background and Objectives: The present systematic review investigated the efficacy of lateral extra-articular tenodesis (LET) and anterolateral ligament (ALL) as lateral extra-articular procedures (LEAPs) for anterior cruciate ligament (ACL) reconstr... Read More about Anterior Cruciate Ligament Reconstruction Using Lateral Extra-Articular Procedures: A Systematic Review.

Augmentation with the inferior extensor retinaculum may facilitate earlier recovery in all-inside arthroscopic management of chronic lateral ankle instability (2025)
Journal Article
Luo, X., Xue, C., Xue, Y., Fehske, K., Zhang, Z.-H., Maffulli, N., …Feng, S.-M. (in press). Augmentation with the inferior extensor retinaculum may facilitate earlier recovery in all-inside arthroscopic management of chronic lateral ankle instability. Journal of Orthopaedic Surgery and Research, 20(1), 1-11. https://doi.org/10.1186/s13018-024-05437-w

Background: To compare the clinical outcomes of inferior extensor retinaculum (IER) augmentation following repair of the anterior talofibular ligament (ATFL) with isolated ATFL repair in patients with an arthroscopically confirmed grade 3 lesion of t... Read More about Augmentation with the inferior extensor retinaculum may facilitate earlier recovery in all-inside arthroscopic management of chronic lateral ankle instability.

Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis. (2024)
Journal Article
Migliorini, F., Schäfer, L., Pilone, M., Bell, A., Simeone, F., & Maffulli, N. (in press). Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis. Archives of Orthopaedic and Trauma Surgery, 145(1), 68. https://doi.org/10.1007/s00402-024-05614-w

The present meta-analysis compared the efficacy of intra-articular hyaluronic acid (HA) injections in patients with early to mild knee osteoarthritis (OA) (Kellgren Lawrence I-II) versus other commonly injected biologically active compounds using pat... Read More about Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis..

Percutaneous repair of the Achilles tendon with one knot offers equivalent results as the same procedure with two knots. A comparative prospective study. (2024)
Journal Article
Maffulli, N., Christidis, G., Gougoulias, N., Christidis, P., Poku, D., Hassan, R., …Oliva, F. (in press). Percutaneous repair of the Achilles tendon with one knot offers equivalent results as the same procedure with two knots. A comparative prospective study. British Medical Bulletin, 1-9. https://doi.org/10.1093/bmb/ldae019

The present prospective comparative study included patients with acute Achilles tendon rupture (ATR) who underwent percutaneous repair with one knot compared to percutaneous repair with two knots. All patients underwent the procedure under local anes... Read More about Percutaneous repair of the Achilles tendon with one knot offers equivalent results as the same procedure with two knots. A comparative prospective study..

Prognostic Factors in Patients Undergoing Physiotherapy for Chronic Low Back Pain: A Level I Systematic Review (2024)
Journal Article
Baroncini, A., Maffulli, N., Pilone, M., Pipino, G., Memminger, M. K., Pappalardo, G., & Migliorini, F. (2024). Prognostic Factors in Patients Undergoing Physiotherapy for Chronic Low Back Pain: A Level I Systematic Review. Journal of Clinical Medicine, 13(22), 1-27. https://doi.org/10.3390/jcm13226864

Background: Low back pain is common. For patients with mechanic or non-specific chronic LBP (cLBP), the current guidelines suggest conservative, nonpharmacologic treatment as a first-line treatment. Among the available strategies, physiotherapy repre... Read More about Prognostic Factors in Patients Undergoing Physiotherapy for Chronic Low Back Pain: A Level I Systematic Review.

Subsidence of the Corail stem in total hip arthroplasty: no influence of bony contact (2024)
Journal Article
Migliorini, F., Maffulli, N., Pilone, M., Kämmer, D., Hofmann, U. K., Nobili, A., …Bell, A. (2024). Subsidence of the Corail stem in total hip arthroplasty: no influence of bony contact. Journal of Orthopaedics and Traumatology, 25(1), 1-9. https://doi.org/10.1186/s10195-024-00794-y

Introduction: This study investigated stem subsidence following primary total hip arthroplasty (THA) with a Corail stem in patients who underwent two-staged bilateral THA. The second outcome of interest was to investigate whether a specific single co... Read More about Subsidence of the Corail stem in total hip arthroplasty: no influence of bony contact.

Management of knee osteoarthritis using bone marrow aspirate concentrate: a systematic review (2024)
Journal Article
Migliorini, F., Pilone, M., Ascani, J., Schäfer, L., Jeyaraman, M., & Maffulli, N. (2024). Management of knee osteoarthritis using bone marrow aspirate concentrate: a systematic review. British Medical Bulletin, 1-13. https://doi.org/10.1093/bmb/ldae016

Introduction Knee osteoarthritis (OA) is a common degenerative joint condition and a major cause of disability in the general population. Source of data Recent published literature identified from PubMed, EMBASE, Google Scholar, and Scopus. Areas of... Read More about Management of knee osteoarthritis using bone marrow aspirate concentrate: a systematic review.

High-volume injections in Achilles tendinopathy: a systematic review (2024)
Journal Article
Hassan, R., Poku, D., Miah, N., & Maffulli, N. (2024). High-volume injections in Achilles tendinopathy: a systematic review. British Medical Bulletin, 1-13. https://doi.org/10.1093/bmb/ldae015

Introduction Achilles tendinopathy (AT) is common, particularly in runners. High-volume injections (HVIs) may be beneficial in the management of AT compared to other conservative management options, including exercise regimens, platelet-rich plasma (... Read More about High-volume injections in Achilles tendinopathy: a systematic review.

Sacroiliac joint pain: what treatment and when. (2024)
Journal Article
Cocconi, F., Maffulli, N., Bell, A., Memminger, M. K., Simeone, F., & Migliorini, F. (in press). Sacroiliac joint pain: what treatment and when. Expert Review of Neurotherapeutics, 1-8. https://doi.org/10.1080/14737175.2024.2400682

Spinal and non-spinal pathologies can cause low back pain. Non-spinal sources of low back pain include the sacroiliac joint (SIJ) and the hip. SIJ pain can be treated either conservatively or surgically. Current strategies for managing sacroiliac joi... Read More about Sacroiliac joint pain: what treatment and when..

Pharmacological management of secondary chronic spinal cord injury: a systematic review (2024)
Journal Article
Migliorini, F., Cocconi, F., Schäfer, L., Simeone, F., Jeyaraman, M., & Maffulli, N. (2024). Pharmacological management of secondary chronic spinal cord injury: a systematic review. British Medical Bulletin, 151(1), 49–68. https://doi.org/10.1093/bmb/ldae009

Introduction Spinal cord injury (SCI) may bring lifelong consequences for affected patients and a high financial burden to the health care system. Source of data Published peer-reviewed scientific articles identified from EMBASE, Google Scholar, PubM... Read More about Pharmacological management of secondary chronic spinal cord injury: a systematic review.

Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Murugan, S., Ramasubramanian, S., Balaji, S., Maffulli, N., & Jeyaraman, M. (in press). Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review. Journal of Clinical Medicine, 13(16), Article 4794. https://doi.org/10.3390/jcm13164794

Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties. Despite being in use since the 1920s, its mechanism of action still n... Read More about Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review.

Angioembolization in the management of joint pain: current concepts. (2024)
Journal Article
Jeyaraman, N., Migliorini, F., Ramkumar, V., Ramasubramanian, S., Patro, B. P., Maffulli, N., & Jeyaraman, M. (in press). Angioembolization in the management of joint pain: current concepts. Die Orthopädie, https://doi.org/10.1007/s00132-024-04531-5

Joint pain is a common complaint owing to its origin in inflammatory and degenerative joint diseases. Recent research has helped narrow down inadequate angiogenesis as one of the causes. Angioembolization has emerged as a treatment option for this co... Read More about Angioembolization in the management of joint pain: current concepts..