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Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. (2025)
Journal Article
Williams, M. M., Smith, N. R., Uyl-de Groot, C. A., den Uil, C. A., Ross, J. S., Mohamed, M. O., …Cram, P. (in press). Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. Circulation: Cardiovascular Quality and Outcomes, Article e011636. https://doi.org/10.1161/CIRCOUTCOMES.124.011636

The authorization process and coverage/reimbursement mechanisms for medical devices play critical roles in device adoption and usage. However, international variation in these processes remains poorly characterized, especially with regard to data tra... Read More about Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries..

Poor glycemic control and its predictors among people living with diabetes in low- and middle-income countries: a systematic review and meta-analysis (2025)
Journal Article
Azagew, A. W., Mekonnen, C. K., Lambie, M., Shepherd, T., & Babatunde, O. O. (in press). Poor glycemic control and its predictors among people living with diabetes in low- and middle-income countries: a systematic review and meta-analysis. BMC Public Health, 25(1), 1-26. https://doi.org/10.1186/s12889-025-21828-y

Introduction: Variability in blood glucose remains a challenge in diabetic management. Therefore, this review aimed to estimate the overall poor glycemic control and identify its predictors among people living with diabetes in low- and middle-income... Read More about Poor glycemic control and its predictors among people living with diabetes in low- and middle-income countries: a systematic review and meta-analysis.

Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis. (2025)
Journal Article
Ibrahim, A., Shalabi, L., Zreigh, S., Ramadan, S., Mourad, S., Eljadid, G., …Mamas, M. (in press). Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis. Catheterization and Cardiovascular Interventions, 1-9. https://doi.org/10.1002/ccd.31461

Left atrial appendage occlusion (LAAO) is an alternative to chronic oral anticoagulation (OAT) for stroke prevention in nonvalvular atrial fibrillation (NVAF) patients with contraindications to OAT. Postprocedure antithrombotic therapy (ATT) is essen... Read More about Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis..

Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis (2025)
Journal Article
Nunes, A. R., Karaba, F., Geddes, O., Bickerton, A., Atherton, H., Dahlmann, F., …Dale, J. (2025). Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis. BMJ Open, 15(2), 1-9. https://doi.org/10.1136/bmjopen-2024-091404

Objectives: To summarise and synthesise existing literature on the implementation of decarbonisation actions in general practice, to outline the actions being implemented, factors influencing decarbonisation, identify evidence gaps and questions for... Read More about Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis.

Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study (2025)
Journal Article
Dafaalla, M., Costa, F., Jia, H., Wijeysundera, H., Rashid, M., Graham, M. M., …Mamas, M. A. (in press). Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study. European Heart Journal Open, Article oeaf012. https://doi.org/10.1093/ehjopen/oeaf012

Background Treatment of patients with cancer presenting with ST-elevation myocardial infarction (STEMI) is complex given the increased risk of both thrombotic and major bleeding complications. Methods A nationally-linked cohort of STEMI patients betw... Read More about Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study.

Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective. (2025)
Journal Article
Doolub, G., Raichman, A., Abramov, D., Bang, V., Parwani, P., Karunanithi, K., …Mamas, M. A. (in press). Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective. Expert Review of Cardiovascular Therapy, 23(1-2), 35-43. https://doi.org/10.1080/14779072.2025.2463332

We present an analysis of cardiovascular-related deaths specific to hematological cancer patients in the United States from 1999 to 2020, examining trends in relation to age, gender, and type of hematological cancer. Utilizing the Multiple Cause of D... Read More about Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective..

The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study (2025)
Journal Article
Allison, K., Nelligan, R. K., Lawford, B., Jones, S. E., Hinman, R. S., Pardo, J., …Bennell, K. L. (in press). The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study. Brazilian Journal of Physical Therapy, 29(2), 1-8. https://doi.org/10.1016/j.bjpt.2025.101172

Background
Exercise and weight loss are core treatments for knee osteoarthritis (OA). While physical therapists are considered well placed to engage in weight management alongside exercise (not replacing dietician care), evidence surrounding physica... Read More about The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study.

Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society (2025)
Journal Article
Curzen, N., Routledge, H., McGrath, S., Abouelasaad, M., Mamas, M., Kinnaird, T., …Hildick-Smith, D. (in press). Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society. Interventional Cardiology: Reviews, Research, Resources, 20, https://doi.org/10.15420/icr.2024.43

Percutaneous techniques to treat obstructive coronary artery disease continue to evolve and the evidence base informing our practice is shared and summarised in international guidelines. In the UK, the British Cardiovascular Intervention Society repr... Read More about Percutaneous Coronary Intervention in the UK: Recommendations of the British Cardiovascular Intervention Society.

Sex differences in patients with working diagnosis of myocardial infarction with nonobstructive coronary arteries (MINOCA) (2025)
Journal Article
Milewski, M., Desperak, A., Koźlik, M., Bujak, M., Gierlotka, M., Milewski, K., …Gasior, P. (in press). Sex differences in patients with working diagnosis of myocardial infarction with nonobstructive coronary arteries (MINOCA). Scientific Reports, 15(1), 1-11. https://doi.org/10.1038/s41598-025-87121-5

Myocardial infarction with nonobstructive coronary arteries (MINOCA) constitutes 3–15% of all acute myocardial infarctions. Women are more frequently diagnosed with MINOCA, although the influence of sex on long-term outcomes is still unclear. In this... Read More about Sex differences in patients with working diagnosis of myocardial infarction with nonobstructive coronary arteries (MINOCA).

Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization (2025)
Journal Article
Averbuch, T., Zafari, A., Islam, S., Lee, S. F., Sankaranarayanan, R., Greene, S. J., …Van Spall, H. G. (in press). Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization. ESC Heart Failure, 1-10. https://doi.org/10.1002/ehf2.15129

Aims: Risk prediction indices used in worsening heart failure (HF) vary in complexity, performance, and the type of datasets in which they were validated. We compared the performance of seven risk prediction indices in a contemporary cohort of patien... Read More about Comparative performance of risk prediction indices for mortality or readmission following heart failure hospitalization.

The impact of specialist cardiology inpatient care on the long-term outcomes of non-ST-segment elevation myocardial infarction (NSTEMI): A nationwide cohort study. (2025)
Journal Article
Moledina, S. M., Weight, N., Cole, A., Rashid, M., Kontopantelis, E., & Mamas, M. A. (in press). The impact of specialist cardiology inpatient care on the long-term outcomes of non-ST-segment elevation myocardial infarction (NSTEMI): A nationwide cohort study. International Journal of Cardiology, 423, 1-10. https://doi.org/10.1016/j.ijcard.2025.132990

Specialist cardiac care has been shown to reduce inpatient mortality following non-ST segment myocardial infarction (NSTEMI), but whether this benefit extends beyond index admission is unclear. Using the linked Myocardial Ischaemia National Audit Pro... Read More about The impact of specialist cardiology inpatient care on the long-term outcomes of non-ST-segment elevation myocardial infarction (NSTEMI): A nationwide cohort study..

Managing thyroid hormone replacement after total thyroidectomy: Guidance for family medicine (2025)
Journal Article
Ahmad, A., Mughal, Z., Jangan, A., Diakos, E., Minhas, S., & Mughal, F. (in press). Managing thyroid hormone replacement after total thyroidectomy: Guidance for family medicine. Journal of Family Medicine and Primary Care, 14(1), 4-7. https://doi.org/10.4103/jfmpc.jfmpc_947_24

Thyroid hormones are among the most prescribed medications to patients worldwide and are commonly used to treat hypothyroidism. Thyroxine is also indicated after total thyroidectomy for Graves’ disease or a multinodular goitre. In this commentary, we... Read More about Managing thyroid hormone replacement after total thyroidectomy: Guidance for family medicine.

A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts. (2025)
Journal Article
Wiseman, J., Basit, R. H., Suto, A., Middya, S., Kabiri, B., Evans, M., …Chari, D. M. (in press). A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts. Neural Regeneration Research, 20(12), 3539-3552. https://doi.org/10.4103/NRR.NRR-D-24-00422

Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies. Biomaterial therapies show promise as medical materials for neural repair through immunomodulation, structural support, and delivery of t... Read More about A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts..

Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach. (2024)
Journal Article
Chew, N. W. S., Mehta, A., Goh, R. S. J., Zhang, A., Chen, Y., Chong, B., …Sperling, L. S. (2025). Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach. Circulation, 151(1), 98-119. https://doi.org/10.1161/CIRCULATIONAHA.124.070535

There is a new awareness of the widespread nature of metabolic dysfunction-associated steatotic liver disease (MASLD) and its connection to cardiovascular disease (CVD). This has catalyzed collaboration between cardiologists, hepatologists, endocrino... Read More about Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach..

How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. (2024)
Journal Article
Murphy, A. C., Carroll, W., Gotsell, M., Potter, C., Quint, J. K., & Malone, R. (in press). How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey. BMJ Open Respiratory Research, 11(1), e002579. https://doi.org/10.1136/bmjresp-2024-002579

Inhalers are widely used for the management of asthma and chronic obstructive pulmonary disease. However, there is little knowledge about the extent to which an inhaler is used and when it is disposed of, despite the implications for an individual's... Read More about How do patients determine when their inhaler is empty? Insights from an analysis of returned inhalers and a patient survey..

Correction: Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. (2024)
Journal Article
Cole, A., Weight, N., Misra, S., Grapsa, J., Rutter, M. K., Siudak, Z., …Mamas, M. A. (in press). Correction: Addressing disparities in the long-term mortality risk in individuals with non-ST segment myocardial infarction (NSTEMI) by diabetes mellitus status: a nationwide cohort study. Diabetologia, https://doi.org/10.1007/s00125-024-06337-8

A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides (2024)
Journal Article
Shen, Z., Simard, M., Brand, D., Andrei, V., Al-Khader, A., Oumlil, F., …Collins-Fekete, C.-A. (in press). A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides. Communications Biology, 7(1), 1674. https://doi.org/10.1038/s42003-024-07398-6

Mitotic activity is an important feature for grading several cancer types. However, counting mitotic figures (cells in division) is a time-consuming and laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incor... Read More about A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides.

Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data. (2024)
Journal Article
Cipolletta, E., Nakafero, G., McCormick, N., Yokose, C., Avery, A. J., Mamas, M. A., …Abhishek, A. (in press). Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data. The Lancet Rheumatology, 1-12. https://doi.org/10.1016/S2665-9913%2824%2900248-0

Initiating urate-lowering therapy can trigger gout flares. Gout flares have been associated with a temporally increased risk of cardiovascular events. Therefore, we aimed to estimate the risk of cardiovascular events in patients with gout initiating... Read More about Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data..