Calcification Microstructure Reflects Breast Tissue Microenvironment (2019)
Journal Article
Gosling, S., Scott, R., Greenwood, C., Bouzy, P., Nallala, J., D. Lyburn, I., …Rogers, K. (2019). Calcification Microstructure Reflects Breast Tissue Microenvironment. Journal of Mammary Gland Biology and Neoplasia, 333-342. https://doi.org/10.1007/s10911-019-09441-3

Microcalcifications are important diagnostic indicators of disease in breast tissue. Tissue microenvironments differ in many aspects between normal and cancerous cells, notably extracellular pH and glycolytic respiration. Hydroxyapatite microcalcific... Read More about Calcification Microstructure Reflects Breast Tissue Microenvironment.

Developing focal construct technology for in vivo diagnosis of osteoporosis (2019)
Conference Proceeding
Greenwood, C., Rogers, K., Wilson, M., Lyburn, I., Evans, P., & Prokopiou, D. (2019). Developing focal construct technology for in vivo diagnosis of osteoporosis. In Journal of Physics: Conference Series. https://doi.org/10.1088/1742-6596/1151/1/012020

Osteoporosis is a prevalent bone disease around the world, characterised by low bone mineral density and increased fracture risk. Currently, the gold standard for identifying osteoporosis and increased fracture risk is through quantification of bone... Read More about Developing focal construct technology for in vivo diagnosis of osteoporosis.

Age Related Changes in Femoral Head Trabecular Architecture (2018)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Rogers, K. (2018). Age Related Changes in Femoral Head Trabecular Architecture. Aging and Disease, 9(6), 976-987. https://doi.org/10.14336/AD.2018.0124

Osteoporosis is a prevalent bone condition, characterised by low bone mineral density and increased fracture risk. Currently, the gold standard for identifying osteoporosis and increased fracture risk is through quantification of bone mineral density... Read More about Age Related Changes in Femoral Head Trabecular Architecture.

Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter (2016)
Journal Article
Dicken, A., Evans, J., Rogers, K., Stone, N., Greenwood, C., Godber, S., …Zioupos, P. (2016). Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter. Scientific reports, 6, Article 29011. https://doi.org/10.1038/srep29011

Osteoporotic fractures present a significant social and economic burden, which is set to rise
commensurately with the aging population. Greater understanding of the physicochemical differences
between osteoporotic and normal conditions will facilit... Read More about Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter.

The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue (2015)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Zioupos, P. (2015). The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue. Bone Reports, 3, 67 - 75. https://doi.org/10.1016/j.bonr.2015.10.001

Osteoporosis is clinically assessed from bone mineral density measurements using dual energy X-ray absorption (DXA). However, these measurements do not always provide an accurate fracture prediction, arguably because DXA does not grapple with ‘bone q... Read More about The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue.

X-ray diffraction from bone employing annular and semi-annular beams (2015)
Journal Article
Dicken, A., Evans, J., Rogers, K., Stone, N., Greenwood, C., Godber, S., …Zioupos, P. (2015). X-ray diffraction from bone employing annular and semi-annular beams. Physics in Medicine and Biology, 60(15), 5803 - 5812. https://doi.org/10.1088/0031-9155/60/15/5803

There is a compelling need for accurate, low cost diagnostics to identify osteotissues that are associated with a high risk of fracture within an individual. To satisfy this requirement the quantification of bone characteristics such as ‘bone quality... Read More about X-ray diffraction from bone employing annular and semi-annular beams.