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How do people with knee osteoarthritis perceive and manage flares? A qualitative study (2021)
Journal Article
Parry, E., Dikomitis, L., Peat, G., & Chew-Graham, C. (2022). How do people with knee osteoarthritis perceive and manage flares? A qualitative study. British Journal of General Practice Open (BJGP Open), 6(2), BJGPO.2021.0086 - BJGPO.2021.0086. https://doi.org/10.3399/BJGPO.2021.0086

Background Acute flares in people with osteoarthritis (OA) are poorly understood. There is uncertainty around the nature of flares, their impact, and how these are managed.

Aim To explore understandings and experiences of flares in people with kne... Read More about How do people with knee osteoarthritis perceive and manage flares? A qualitative study.

Best-practice clinical management of flares in people with osteoarthritis: A scoping review of behavioral, lifestyle and adjunctive treatments. (2021)
Journal Article
Bowden, J. L., Kobayashi, S., Hunter, D. J., Mills, K., Peat, G., Guillemin, F., …Eyles, J. P. (2021). Best-practice clinical management of flares in people with osteoarthritis: A scoping review of behavioral, lifestyle and adjunctive treatments. Seminars in Arthritis and Rheumatism, 51(4), 749 - 760. https://doi.org/10.1016/j.semarthrit.2021.04.017

INTRODUCTION: Transient episodes of increased pain, stiffness or swelling are common in people with osteoarthritis (OA). Yet, evidence-based management strategies for lessening the impact of OA flares are rarely covered in clinical guidelines and hav... Read More about Best-practice clinical management of flares in people with osteoarthritis: A scoping review of behavioral, lifestyle and adjunctive treatments..

Triggers for acute flare in adults with, or at risk of, knee osteoarthritis: a web-based case-crossover study in community-dwelling adults. (2021)
Journal Article
Thomas, M., Rathod-Mistry, T., Parry, E., Pope, C., Neogi, T., & Peat, G. (2021). Triggers for acute flare in adults with, or at risk of, knee osteoarthritis: a web-based case-crossover study in community-dwelling adults. Osteoarthritis and Cartilage, 29(7), 956-964. https://doi.org/10.1016/j.joca.2021.04.007

OBJECTIVE: To identify proximate causes ('triggers') of flares in adults with, or at risk of, knee osteoarthritis (OA), estimate their course and consequences, and determine higher risk individuals. METHODS: In this 13-week web-based case-crossover s... Read More about Triggers for acute flare in adults with, or at risk of, knee osteoarthritis: a web-based case-crossover study in community-dwelling adults..

Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis (2019)
Journal Article
Thomas, M., Yu, D., Nicholls, E., Bierma‐Zeinstra, S., Conaghan, P. G., Stoner, K. J., …Peat, G. (2020). Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis. Arthritis Care and Research, 72(12), 1687-1692. https://doi.org/10.1002/acr.24088

Objective
To identify distinct recovery trajectories of acute flares of knee pain and associated participant characteristics.

Methods
Data were from FLARE RCT, a multicentre trial in 27 primary care centres in UK and Netherlands of three regimes... Read More about Short-term recovery trajectories of acute flares in knee pain: a UK-Netherlands multi-centre prospective cohort analysis.

‘Acute Flare-Ups’ In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis (2019)
Report
Parry, E., Ogollah, R., & Peat, G. (2019). ‘Acute Flare-Ups’ In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis

Objective
To determine the natural history of flare-ups in knee osteoarthritis and their relation to physical exposures.

Design
Adults aged =45 years with a recent primary care consultation for knee OA/arthralgia completed a daily pen-and-paper... Read More about ‘Acute Flare-Ups’ In Patients With, Or At High Risk Of, Knee Osteoarthritis: A Daily Diary Study With Case-Crossover Analysis.

Significant pain variability in persons with, or at high risk of, knee osteoarthritis: preliminary investigation based on secondary analysis of cohort data (2017)
Journal Article
Parry, E., Ogollah, R., & Peat, G. (2017). Significant pain variability in persons with, or at high risk of, knee osteoarthritis: preliminary investigation based on secondary analysis of cohort data. BMC Musculoskeletal Disorders, 18, Article 80. https://doi.org/10.1186/s12891-017-1434-3

BACKGROUND: While knee osteoarthritis (OA) is characterised as a slowly progressive disease, acute flares, episodes of severe pain, and substantial fluctuations in pain intensity appear to be part of the natural history for some patients. We sought t... Read More about Significant pain variability in persons with, or at high risk of, knee osteoarthritis: preliminary investigation based on secondary analysis of cohort data.

Prodromal symptoms in knee osteoarthritis: a nested case–control study using data from the Osteoarthritis Initiative (2015)
Journal Article
Case, R., Thomas, E., Clarke, E., & Peat, G. (2015). Prodromal symptoms in knee osteoarthritis: a nested case–control study using data from the Osteoarthritis Initiative. Osteoarthritis and Cartilage, 23(7), 1083 - 1089. https://doi.org/10.1016/j.joca.2014.12.026

OBJECTIVE: In order to gain a better understanding of the timing of emergent symptoms of osteoarthritis, we sought to investigate the existence, duration and nature of a prodromal symptomatic phase preceding incident radiographic knee osteoarthritis... Read More about Prodromal symptoms in knee osteoarthritis: a nested case–control study using data from the Osteoarthritis Initiative.