Skip to main content

Research Repository

Advanced Search

THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE (2021)
Presentation / Conference
Roffe, C., Bath, P., Warusevitane, A., Smith, C., Dixit, A., Sprigg, N., …Ogollah, R. (2021, November). THE METOCLOPRAMIDE FOR AVOIDING PNEUMONIA AFTER STROKE (MAPS-2) TRIAL: A SINGLE-BLIND RCT OF METOCLOPRAMIDE FOR THE PREVENTION OF PNEUMONIA IN PATIENTS WITH DYSPHAGIA AFTER STROKE. Presented at UK Stroke Forum 2021, Virtual

Sensory Stimulation of the Foot and Ankle Early Post-stroke: A Pilot and Feasibility Study (2021)
Journal Article
Aries, A., Pomeroy, V., Sim, J., Read, S., & Hunter, S. (2021). Sensory Stimulation of the Foot and Ankle Early Post-stroke: A Pilot and Feasibility Study. Frontiers in Neurology, https://doi.org/10.3389/fneur.2021.675106

Background: Somatosensory stimulation of the lower extremity could improve motor recovery and walking post-stroke. This pilot study investigated the feasibility of a subsequent randomized controlled trial (RCT) to determine whether task-specific gait... Read More about Sensory Stimulation of the Foot and Ankle Early Post-stroke: A Pilot and Feasibility Study.

Mechanical thrombectomy: can it be safely delivered out of hours in the UK? (2020)
Journal Article
Weddell, J., Parr, E., Knight, S., Muddegowda, G., Natarajan, I., Chembala, J., …Roffe, C. (2020). Mechanical thrombectomy: can it be safely delivered out of hours in the UK?. BMC Neurology, 20, Article 326. https://doi.org/10.1186/s12883-020-01909-8

BACKGROUND: Mechanical thrombectomy was approved by NICE as a treatment for stroke in 2016. However, most of the evidence is from studies conducted during working hours. Only few centres in the UK perform thrombectomies out-of-hours. The Royal Stoke... Read More about Mechanical thrombectomy: can it be safely delivered out of hours in the UK?.

Cardiopulmonary Function and Aerobic Exercise in Parkinson's: A Systematic Review of the Literature (2020)
Journal Article
Aburub, A., Ledger, S. J., Sim, J., & Hunter, S. (2020). Cardiopulmonary Function and Aerobic Exercise in Parkinson's: A Systematic Review of the Literature. Movement Disorders Clinical Practice, 599-606. https://doi.org/10.1002/mdc3.13011

Background
Cardiorespiratory impairments are considered the main cause of mortality in the late stages of Parkinson's. Aerobic exercise has been shown to improve pulmonary function in asthmatic patients and in healthy people. However, effects of aer... Read More about Cardiopulmonary Function and Aerobic Exercise in Parkinson's: A Systematic Review of the Literature.

Authors' reply re: Laparoscopic ablation or excision with helium thermal coagulator versus electrodiathermy for the treatment of mild-to-moderate endometriosis: randomised controlled trial (2020)
Journal Article
Misra, G., Sim, J., Watts, K., & Coia, T. (2020). Authors' reply re: Laparoscopic ablation or excision with helium thermal coagulator versus electrodiathermy for the treatment of mild-to-moderate endometriosis: randomised controlled trial. BJOG: An International Journal of Obstetrics and Gynaecology, 127(12), https://doi.org/10.1111/1471-0528.16333

'No abstract'

The experience of upper-limb dysfunction after stroke: a phenomenological study (2020)
Journal Article
Purton, J., Sim, J., & Hunter, S. (2020). The experience of upper-limb dysfunction after stroke: a phenomenological study. Disability and Rehabilitation, 43(23), 1 - 10. https://doi.org/10.1080/09638288.2020.1743775

Background: Stroke can bring about a profound disruption to people's lives, but what is less understood is the effect that specific dysfunctions can have. The aim of this study was to explore stroke survivors' experiences of upper-limb dysfunction ov... Read More about The experience of upper-limb dysfunction after stroke: a phenomenological study.

Interpreting intracorporeal landscapes: how patients visualize pathophysiology and utilize medical images in their understanding of chronic musculoskeletal illness (2018)
Journal Article
Moore, A. J., Richardson, J. C., Bernard, M., & Sim, J. (2019). Interpreting intracorporeal landscapes: how patients visualize pathophysiology and utilize medical images in their understanding of chronic musculoskeletal illness. Disability and Rehabilitation, 41(14), 1647 - 1654. https://doi.org/10.1080/09638288.2018.1443162

Medical science and other sources, such as the media, increasingly inform the general public's understanding of disease. There is often discordance between this understanding and the diagnostic interpretations of health care practitioners (HCPs). In... Read More about Interpreting intracorporeal landscapes: how patients visualize pathophysiology and utilize medical images in their understanding of chronic musculoskeletal illness.

Feasibility of a randomized single-blind crossover trial to assess the effects of the second-generation slow-release dopamine agonists pramipexole and ropinirole on cued recall memory in idiopathic mild or moderate Parkinson’s disease without cognitive impairment (2017)
Journal Article
Shepherd, T. A., Edelstyn, N. M., Longshaw, L., Sim, J., Watts, K., Mayes, A. R., …Ellis, S. J. (2017). Feasibility of a randomized single-blind crossover trial to assess the effects of the second-generation slow-release dopamine agonists pramipexole and ropinirole on cued recall memory in idiopathic mild or moderate Parkinson’s disease without cognitive impairment. Pilot and Feasibility Studies, https://doi.org/10.1186/s40814-017-0154-7

BACKGROUND: The aim was to assess the feasibility of a single-centre, single-blind, randomized, crossover design to explore the effects of two slow-release dopamine agonists, ropinirole and pramipexole, on cued recall in Parkinson's disease. As the d... Read More about Feasibility of a randomized single-blind crossover trial to assess the effects of the second-generation slow-release dopamine agonists pramipexole and ropinirole on cued recall memory in idiopathic mild or moderate Parkinson’s disease without cognitive impairment.

Rationale and design of BISTRO: a randomized controlled trial to determine whether bioimpedance spectroscopy-guided fluid management maintains residual kidney function in incident haemodialysis patients (2017)
Journal Article
Davie, S., Coyle, D., Dasgupta, I., Andronis, L., Farrington, K., Wilkie, M., …Caskey, F. (2017). Rationale and design of BISTRO: a randomized controlled trial to determine whether bioimpedance spectroscopy-guided fluid management maintains residual kidney function in incident haemodialysis patients. BMC Nephrology, 18, Article 138. https://doi.org/10.1186/s12882-017-0554-1

BACKGROUND: Preserved residual kidney function (RKF) and normal fluid status are associated with better patient outcomes in incident haemodialysis patients. The objective of this trial is to determine whether using bioimpedance technology in prescrib... Read More about Rationale and design of BISTRO: a randomized controlled trial to determine whether bioimpedance spectroscopy-guided fluid management maintains residual kidney function in incident haemodialysis patients.

The stroke oxygen pilot study: a randomized controlled trial of the effects of routine oxygen supplementation early after acute stroke--effect on key outcomes at six months (2013)
Journal Article
Ali, K., Warusevitane, A., Lally, F., Sim, J., Sills, S., Pountain, S., …Roffe, C. (2013). The stroke oxygen pilot study: a randomized controlled trial of the effects of routine oxygen supplementation early after acute stroke--effect on key outcomes at six months. PloS one, 8(6), Article e59274. https://doi.org/10.1371/journal.pone.0059274

INTRODUCTION: Post-stroke hypoxia is common, and may adversely affect outcome. We have recently shown that oxygen supplementation may improve early neurological recovery. Here, we report the six-month outcomes of this pilot study. METHODS: Patients w... Read More about The stroke oxygen pilot study: a randomized controlled trial of the effects of routine oxygen supplementation early after acute stroke--effect on key outcomes at six months.