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Mechanisms Underlying the Association of Chronic Obstructive Pulmonary Disease With Heart Failure (2021)
Journal Article
Lagan LEKARZ, J., Schelbert, E. B., Naish, J. H., Vestbo, J., Fortune, C., Bradley, J., …Miller, C. A. (2021). Mechanisms Underlying the Association of Chronic Obstructive Pulmonary Disease With Heart Failure. JACC: Cardiovascular Imaging, 14(10), 1963-1973. https://doi.org/10.1016/j.jcmg.2021.03.026

OBJECTIVES: The purposes of this study were to determine why chronic obstructive pulmonary disease (COPD) is associated with heart failure (HF). Specific objectives included whether COPD is associated with myocardial fibrosis, whether myocardial fibr... Read More about Mechanisms Underlying the Association of Chronic Obstructive Pulmonary Disease With Heart Failure.

Implications for the design of a Diagnostic Decision Support System (DDSS) to reduce time and cost to diagnosis in paediatric shoulder instability (2021)
Journal Article
Faux-Nightingale, A., De Quincey, E., Philp, F., Woolley, S., Pandyan, A., & de Quincey, E. (in press). Implications for the design of a Diagnostic Decision Support System (DDSS) to reduce time and cost to diagnosis in paediatric shoulder instability. BMC Medical Informatics and Decision Making, 21(1), Article ARTN 78. https://doi.org/10.1186/s12911-021-01446-5

<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Currently the diagnosis of shoulder instability, particularly in children, is difficult and can take time. These diagnostic delays can lead to poorer outcome and... Read More about Implications for the design of a Diagnostic Decision Support System (DDSS) to reduce time and cost to diagnosis in paediatric shoulder instability.

The Effect of Pain Conditioning on Experimentally Evoked Cough: Evidence of Impaired Endogenous Inhibitory Control Mechanisms in Refractory Chronic Cough (2020)
Journal Article
Hilton, E., Satia, I., Holt, K., Woodcock, A. A., Belcher, J., & Smith, J. A. (2020). The Effect of Pain Conditioning on Experimentally Evoked Cough: Evidence of Impaired Endogenous Inhibitory Control Mechanisms in Refractory Chronic Cough. European Respiratory Journal, 56(6), 2001387 - 2001387. https://doi.org/10.1183/13993003.01387-2020

Background: The pathophysiology of refractory chronic cough (RCC) is unclear. We hypothesised that endogenous inhibitory control mechanisms, such as those activated by painful stimuli (conditioned pain modulation (CPM)), may be capable of inhibiting... Read More about The Effect of Pain Conditioning on Experimentally Evoked Cough: Evidence of Impaired Endogenous Inhibitory Control Mechanisms in Refractory Chronic Cough.

Predictive equation for optimal continuous positive airway pressure in children with obstructive sleep apnoea (2020)
Journal Article
Chong, J., Bajpai, R., Teoh, O. H., Pugalenthi, A., Allen, J. C., Cheng, Z. R., …Thomas, B. (2020). Predictive equation for optimal continuous positive airway pressure in children with obstructive sleep apnoea. ERJ Open Research, 6(2), Article 00312-2019. https://doi.org/10.1183/23120541.00312-2019

<jats:sec><jats:title>Aim</jats:title><jats:p>A subgroup of children with obstructive sleep apnoea (OSA) requires treatment with continuous positive airway pressure (CPAP). This study's aims were: 1) to determine if the optimal CPAP for the treatment... Read More about Predictive equation for optimal continuous positive airway pressure in children with obstructive sleep apnoea.

Development and validation of a Patient Reported Experience Measure (PREM) for patients with rheumatoid arthritis (RA) and other rheumatic conditions (2015)
Journal Article
O'Brien, A., Bosworth, A., Cox, M., Jones, P., Sargeant, I., Elliot, A., & Bukhari, M. (2015). Development and validation of a Patient Reported Experience Measure (PREM) for patients with rheumatoid arthritis (RA) and other rheumatic conditions. Current Rheumatology Reviews, 1-7. https://doi.org/10.2174/1573397111666150522093712

Methods: Focus groups were held with RA patients to identify key elements of the patient experience. These were mapped against the UK Department of Health Patient Experience Framework and a PREM questionnaire developed with questions specifically rel... Read More about Development and validation of a Patient Reported Experience Measure (PREM) for patients with rheumatoid arthritis (RA) and other rheumatic conditions.