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Dementia, women and sexuality: how the intersection of ageing, gender and sexuality magnify dementia concerns among lesbian and bisexual women (2014)
Journal Article
(2014). Dementia, women and sexuality: how the intersection of ageing, gender and sexuality magnify dementia concerns among lesbian and bisexual women. Dementia, 1494-1514. https://doi.org/10.1177/1471301214564446

There is a growing appreciation of the significance of socio-cultural context for the experiences of an individual living with dementia. There is, too, an emergent awareness that dementia is a gendered issue, disproportionately affecting women compar... Read More about Dementia, women and sexuality: how the intersection of ageing, gender and sexuality magnify dementia concerns among lesbian and bisexual women.

Acceptability of a 'guidebook' for the management of Osteoarthritis: a qualitative study of patient and clinician's perspectives (2014)
Journal Article
Morden, A., Jinks, C., Nio Ong, B., Porcheret, M., & Dziedzic, K. S. (2014). Acceptability of a 'guidebook' for the management of Osteoarthritis: a qualitative study of patient and clinician's perspectives. BMC Musculoskeletal Disorders, 15, Article 427. https://doi.org/10.1186/1471-2474-15-427

BACKGROUND: Written information can be of benefit to both practitioners and patients and the provision of quality information is emphasised as a core intervention by United Kingdom National Institute of Clinical Excellence (NICE) OA guidelines. Resea... Read More about Acceptability of a 'guidebook' for the management of Osteoarthritis: a qualitative study of patient and clinician's perspectives.

Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity? (2014)
Journal Article
Marshall, M., Nicholls, E., Kwok, W., Peat, G., Kloppenburg, M., Van Der Windt, D., …Dziedzic, K. (2014). Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity?. Annals of the Rheumatic Diseases, 74(1), 136 - 141. https://doi.org/10.1136/annrheumdis-2013-203948

OBJECTIVES: To determine whether erosive osteoarthritis shares the same pattern of joint involvement and risk profile as increasing grades of non-erosive hand osteoarthritis. METHODS: Participants were from two population-based cohorts, aged =50 year... Read More about Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity?.

Measurement properties of asthma-specific quality-of-life measures: protocol for a systematic review (2014)
Journal Article
Apfelbacher, C., Paudyal, P., Bülbül, A., & Smith, H. (2014). Measurement properties of asthma-specific quality-of-life measures: protocol for a systematic review. Systematic Reviews, https://doi.org/10.1186/2046-4053-3-83

Background Asthma is a frequent chronic inflammatory disease of the airways, and the assessment of health-related quality of life (HrQoL) is important in both research and routine care. Various asthma-specific measures of HrQoL exist but there is unc... Read More about Measurement properties of asthma-specific quality-of-life measures: protocol for a systematic review.

Understanding the challenges to implementing case management for people with dementia in English primary care using Normalisation Process Theory (2014)
Journal Article
Chew-Graham. (2014). Understanding the challenges to implementing case management for people with dementia in English primary care using Normalisation Process Theory. BMC Health Services Research, https://doi.org/10.1186/s12913-014-0549-6

Background
Case management has been suggested as a way of improving the quality and cost-effectiveness of support for people with dementia. In this study we adapted and implemented a successful United States’ model of case management in primary care... Read More about Understanding the challenges to implementing case management for people with dementia in English primary care using Normalisation Process Theory.

Demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis: cross-sectional findings from the Clinical Assessment Study of the Foot (2014)
Journal Article
Menz, H., Roddy, E., Marshall, M., Thomas, M., Rathod, T., Myers, H., …Peat, G. (2015). Demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis: cross-sectional findings from the Clinical Assessment Study of the Foot. Osteoarthritis and Cartilage, 23(1), 77 -82. https://doi.org/10.1016/j.joca.2014.10.007

OBJECTIVE: To explore demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis (OA) (First MTPJ OA). DESIGN: Adults aged =50 years registered with four general practices were mailed a He... Read More about Demographic and clinical factors associated with radiographic severity of first metatarsophalangeal joint osteoarthritis: cross-sectional findings from the Clinical Assessment Study of the Foot.

Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials (2014)
Journal Article
Oppong, R., Jowett, S., Nicholls, E., Whitehurst, D., Hill, S., Hammond, A., …Dziedzic, K. (2015). Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials. Rheumatology, 54(5), 876 - 883. https://doi.org/10.1093/rheumatology/keu389

OBJECTIVES: Evidence regarding the cost-effectiveness of joint protection and hand exercises for the management of hand OA is not well established. The primary aim of this study is to assess the cost-effectiveness (cost-utility) of these management o... Read More about Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials.

A motivational intervention for patients with COPD in primary care: qualitative evaluation of a new practitioner role (2014)
Journal Article
Langer, S., Chew-Graham, C. A., Drinkwater, J., Afzal, C., Keane, K., Hunter, C., …Salmon, P. (2014). A motivational intervention for patients with COPD in primary care: qualitative evaluation of a new practitioner role. BMC Family Practice, 15, Article 164. https://doi.org/10.1186/1471-2296-15-164

BACKGROUND: Long-term conditions such as chronic obstructive pulmonary disease (COPD) are growing challenges for health services. Psychosocial co-morbidity is associated with poorer quality of life and greater use of health care in these patients but... Read More about A motivational intervention for patients with COPD in primary care: qualitative evaluation of a new practitioner role.

Bacterial distribution in the lungs of children with protracted bacterial bronchitis (2014)
Journal Article
Narang, R., Bakewell, K., Peach, J., Clayton, S., Samuels, M., Alexander, J., …Gilchrist, F. J. (2014). Bacterial distribution in the lungs of children with protracted bacterial bronchitis. PloS one, 9(9), Article e108523. https://doi.org/10.1371/journal.pone.0108523

OBJECTIVES: Flexible bronchoscopy with bronchoalveolar lavage (FB-BAL) is increasingly used for the microbiological confirmation of protracted bacterial bronchitis (PBB) in children with a chronic wet cough. At our centre, when performing FB-BAL for... Read More about Bacterial distribution in the lungs of children with protracted bacterial bronchitis.

Symptom complexes in patients with seropositive arthralgia and in patients newly diagnosed with rheumatoid arthritis: a qualitative exploration of symptom development. (2014)
Journal Article
Mallen. (2014). Symptom complexes in patients with seropositive arthralgia and in patients newly diagnosed with rheumatoid arthritis: a qualitative exploration of symptom development. https://doi.org/10.1093/rheumatology/keu159

OBJECTIVE: The aim of this study was to explore symptoms and symptom development during the earliest phases of RA in patients with seropositive arthralgia and patients newly diagnosed with RA. METHODS: Interviews were conducted with 15 seropositive p... Read More about Symptom complexes in patients with seropositive arthralgia and in patients newly diagnosed with rheumatoid arthritis: a qualitative exploration of symptom development..

Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations. (2014)
Journal Article
(2014). Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations. Journal of Neurology, 1662 - 1676. https://doi.org/10.1007/s00415-013-7209-3

Neuro-Behçet's disease (NBD) is one of the more serious manifestations of Behçet's disease (BD), which is a relapsing inflammatory multisystem disease with an interesting epidemiology. Though NBD is relatively uncommon, being potentially treatable, n... Read More about Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations..

Implementing the NICE osteoarthritis guidelines: a mixed methods study and cluster randomised trial of a model osteoarthritis consultation in primary care - the Management of OsteoArthritis In Consultations (MOSAICS) study protocol (2014)
Journal Article
Dziedzic, K. S., Healey, E. L., Porcheret, M., Nio Ong, B., Main, C. J., Jordan, K. P., …Hay, E. M. (2014). Implementing the NICE osteoarthritis guidelines: a mixed methods study and cluster randomised trial of a model osteoarthritis consultation in primary care - the Management of OsteoArthritis In Consultations (MOSAICS) study protocol. Implementation Science, 9, Article 95. https://doi.org/10.1186/s13012-014-0095-y

Backgroundhere is as yet no evidence on the feasibility of implementing recommendations from the National Institute of Health and Care Excellence (NICE) osteoarthritis (OA) guidelines in primary care, or of the effect these recommendations on the con... Read More about Implementing the NICE osteoarthritis guidelines: a mixed methods study and cluster randomised trial of a model osteoarthritis consultation in primary care - the Management of OsteoArthritis In Consultations (MOSAICS) study protocol.

Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice (2014)
Journal Article
Kehoe, O., Kalia, N., King, S., Eustace, A., Middleton, J., Boyes, C., …Patterson, A. (2014). Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice. Arthritis Research and Therapy, R148 -?. https://doi.org/10.1186/ar4610

INTRODUCTION: Syndecans are heparan sulphate proteoglycans expressed by endothelial cells. Syndecan-3 is expressed by synovial endothelial cells of rheumatoid arthritis (RA) patients where it binds chemokines, suggesting a role in leukocyte trafficki... Read More about Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice.

Clinicalcodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records (2014)
Journal Article
(2014). Clinicalcodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records. PloS one, e99825 - e99825. https://doi.org/10.1371/journal.pone.0099825

Lists of clinical codes are the foundation for research undertaken using electronic medical records (EMRs). If clinical code lists are not available, reviewers are unable to determine the validity of research, full study replication is impossible, re... Read More about Clinicalcodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records.

'...I've found once the weight had gone off, i've had a few twinges, but nothing like before'. Exploring weight and self-management of knee pain. (2014)
Journal Article
Jinks. (2014). '...I've found once the weight had gone off, i've had a few twinges, but nothing like before'. Exploring weight and self-management of knee pain. Musculoskeletal Care, 63 - 73. https://doi.org/10.1002/msc.1054

OBJECTIVES: Being overweight or obese is a key risk factor for the onset and exacerbation of knee pain. Policy and clinical guidelines encourage lifestyle changes as part of prevention or supported self-management. The present study explores how peop... Read More about '...I've found once the weight had gone off, i've had a few twinges, but nothing like before'. Exploring weight and self-management of knee pain..

Impact of pain intensity on relationship quality between couples where one has back pain (2014)
Journal Article
Vivekanantham, A., Campbell, P., Mallen, C., & Dunn, K. (2014). Impact of pain intensity on relationship quality between couples where one has back pain. Pain Medicine, 832 - 841. https://doi.org/10.1111/pme.12366

OBJECTIVES: To investigate associations of pain intensity in those with long-term back pain, with their partners' rating of key constructs of relationship quality: cohesion (activities together), consensus (affection, sexual relations), satisfaction... Read More about Impact of pain intensity on relationship quality between couples where one has back pain.

The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry (2014)
Journal Article
Fuller, H. R., Hurtado, M. L., Wishart, T. M., & Gates, M. A. (2014). The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry. Proteome Science, 1-20. https://doi.org/10.1186/1477-5956-12-20

BACKGROUND: Idiopathic Parkinson's disease is marked by degeneration of dopamine neurons projecting from the substantia nigra to the striatum. Although proteins expressed by the target striatum can positively affect the viability and growth of dopami... Read More about The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry.

Development of a behaviour change intervention: a case study on the practical application of theory (2014)
Journal Article
Porcheret, M., Main, C., Croft, P., McKinley, R., Hassell, A., & Dziedzic, K. (2014). Development of a behaviour change intervention: a case study on the practical application of theory. Implementation Science, 9, Article 42. https://doi.org/10.1186/1748-5908-9-42

BACKGROUND: Use of theory in implementation of complex interventions is widely recommended. A complex trial intervention, to enhance self-management support for people with osteoarthritis (OA) in primary care, needed to be implemented in the Managing... Read More about Development of a behaviour change intervention: a case study on the practical application of theory.

Changing policy and practice: making sense of national guidelines for osteoarthritis. (2014)
Journal Article
Dziedzic, & jinks. (2014). Changing policy and practice: making sense of national guidelines for osteoarthritis. Social Science and Medicine, 101 -109. https://doi.org/10.1016/j.socscimed.2014.01.036

Understanding uptake of complex interventions is an increasingly prominent area of research. The interplay of macro (such as changing health policy), meso (re-organisation of professional work) and micro (rationalisation of clinical care) factors upo... Read More about Changing policy and practice: making sense of national guidelines for osteoarthritis..