Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome (2020)
Journal Article
Rashid, & Mamas. (2020). Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome. International Journal of Cardiology, https://doi.org/10.1016/j.ijcard.2020.12.063

Background
Risk factors for further bleeding and ischemic events after acute coronary syndrome (ACS) often overlap. Little is known about sex-based differences in the management and outcomes of ACS patients according to their combined bleeding-ische... Read More about Sex differences in distribution, management and outcomes of combined ischemic-bleeding risk following acute coronary syndrome.

Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis. (2020)
Journal Article
Mamas. (2020). Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis. European Journal of Epidemiology, https://doi.org/10.1007/s10654-020-00710-8

The role of dietary calcium in cardiovascular disease prevention is unclear. We aimed to determine the association between calcium intake and incident cardiovascular disease and mortality. Data were extracted from the European Prospective Investigati... Read More about Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis..

Paclitaxel is effective for controlling astrocyte proliferation in vitro: Implications for generating ventral mesencephalic cultures enriched with dopamine neurons. (2020)
Journal Article
Gómez-Gálvez, Y., & Gates, M. (2020). Paclitaxel is effective for controlling astrocyte proliferation in vitro: Implications for generating ventral mesencephalic cultures enriched with dopamine neurons. Journal of Neuroscience Methods, 109065 - ?. https://doi.org/10.1016/j.jneumeth.2020.109065

BACKGROUND: Primary embryonic ventral mesencephalic (VM) cultures are a high throughput tool for understanding and manipulating dopamine neurons, to study the mechanisms that trigger their degeneration during Parkinson's disease (PD), and to test new... Read More about Paclitaxel is effective for controlling astrocyte proliferation in vitro: Implications for generating ventral mesencephalic cultures enriched with dopamine neurons..

Indicators of dementia disease progression in primary care: an electronic health record cohort study (2020)
Journal Article
Rathod-Mistry, T., Marshall, M., Campbell, P., Bailey, J., Chew-Graham, C. A., Croft, P., …Jordan, K. P. (2021). Indicators of dementia disease progression in primary care: an electronic health record cohort study. European Journal of Neurology, 28(5), 1499-1510. https://doi.org/10.1111/ene.14710

BACKGROUND: The objectives were to assess the feasibility and validity of using markers of dementia-related health as indicators of dementia progression in primary care, by assessing the frequency they are recorded and by testing the hypothesis they... Read More about Indicators of dementia disease progression in primary care: an electronic health record cohort study.

Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes. (2020)
Journal Article
Roddy, & Mamas. (2020). Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes. American Journal of Cardiovascular Drugs, https://doi.org/10.1007/s40256-020-00459-1

Hyperuricemia and gout have been linked to an increased risk for cardiovascular (CV) disease, stroke, hypertension, heart failure, and chronic kidney disease, possibly through a proinflammatory milieu. However, not all the drugs used in gout treatmen... Read More about Gout Pharmacotherapy in Cardiovascular Diseases: A Review of Utility and Outcomes..

Rehabilitation following rotator cuff repair: A nested qualitative study exploring the perceptions and experiences of participants in a randomised controlled trial (2020)
Journal Article
(2020). Rehabilitation following rotator cuff repair: A nested qualitative study exploring the perceptions and experiences of participants in a randomised controlled trial. Clinical Rehabilitation, 269215520984025 - ?

OBJECTIVE: To investigate acceptability, barriers to adherence with the interventions, and which outcome measures best reflect the participants' rehabilitation goals in a pilot and feasibility randomised controlled trial evaluating early patient-dire... Read More about Rehabilitation following rotator cuff repair: A nested qualitative study exploring the perceptions and experiences of participants in a randomised controlled trial.

Acute glycaemic management before, during and after exercise for cardiac rehabilitation participants with diabetes mellitus: a joint statement of the British and Canadian Associations of Cardiovascular Prevention and Rehabilitation, the International Council for Cardiovascular Prevention and Rehabilitation and the British Association of Sport and Exercise Sciences. (2020)
Journal Article
Buckley, J., Riddell, M., Mellor, D., Bracken, R., Poirier, P., LaGerche, A., & Ross, M. (2020). Acute glycaemic management before, during and after exercise for cardiac rehabilitation participants with diabetes mellitus: a joint statement of the British and Canadian Associations of Cardiovascular Prevention and Rehabilitation, the International Council for Cardiovascular Prevention and Rehabilitation and the British Association of Sport and Exercise Sciences. British Journal of Sports Medicine, https://doi.org/10.1136/bjsports-2020-102446

Type 1 (T1) and type 2 (T2) diabetes mellitus (DM) are significant precursors and comorbidities to cardiovascular disease and prevalence of both types is still rising globally. Currently,~25% of participants (and rising) attending cardiac rehabilitat... Read More about Acute glycaemic management before, during and after exercise for cardiac rehabilitation participants with diabetes mellitus: a joint statement of the British and Canadian Associations of Cardiovascular Prevention and Rehabilitation, the International Council for Cardiovascular Prevention and Rehabilitation and the British Association of Sport and Exercise Sciences..

Place and causes of acute cardiovascular mortality during the COVID-19 pandemic. (2020)
Journal Article
Mamas. (2020). Place and causes of acute cardiovascular mortality during the COVID-19 pandemic. Heart, 113-119. https://doi.org/10.1101/2020.07.14.20153734

Objective. To describe the place and causes of acute cardiovascular death during the COVID-19 pandemic.
Methods. Retrospective cohort of adult (age =18 years) acute cardiovascular deaths (n=587,225) in England and Wales, 1st January 2014 to 30th Jun... Read More about Place and causes of acute cardiovascular mortality during the COVID-19 pandemic..

How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia. (2020)
Journal Article
Allen, K., Damery, S. L., Sein, K., Johnson, D. W., Davies, S. J., Lambie, M., …Combes, G. M. (2020). How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 42(3), https://doi.org/10.1177/0896860820975596

BACKGROUND: While numerous studies have explored the patient experience of dialysis or other end-stage kidney disease (ESKD) treatments, few have explored the process of transitioning between dialysis modalities. This study aimed to develop an in-dep... Read More about How do patients and their family members experience the transition from peritoneal dialysis to incentre haemodialysis? A multisite qualitative study in England and Australia..

Struggling for normality: experiences of patients with diabetic lower extremity amputations and post-amputation wounds in primary care. (2020)
Journal Article
(2020). Struggling for normality: experiences of patients with diabetic lower extremity amputations and post-amputation wounds in primary care. Primary Health Care Research and Development, -. https://doi.org/10.1017/S146342362000064X%5BOpens+in+a+new+window%5D

AIM: To explore the experiences of patients living with diabetic lower extremity amputation (DLEA) and its post-amputation wound in primary care. BACKGROUND: DLEA, including both minor and major amputation, is a life-altering condition that brings nu... Read More about Struggling for normality: experiences of patients with diabetic lower extremity amputations and post-amputation wounds in primary care..

Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. (2020)
Journal Article
Twohig, H., Owen, C., Muller, S., Mallen, C., Mitchell, C., Hider, S., …Hill, C. (2021). Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review. Journal of Rheumatology, 48(6), 883-893. https://doi.org/10.3899/jrheum.200248

OBJECTIVE: To systematically identify the outcome measures and instruments used in clinical studies of polymyalgia rheumatica (PMR) and to evaluate evidence about their measurement properties. METHODS: Searches based on the MeSH term 'polymyalgia rhe... Read More about Outcomes Measured in Polymyalgia Rheumatica and Measurement Properties of Instruments Considered for the OMERACT Core Outcome Set: A Systematic Review..

Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR) (2020)
Journal Article
Littlewood, C., Bateman, M., Butler-Walley, S., Bathers, S., Bromley, K., Lewis, M., …Foster, N. E. (2020). Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR). Clinical Rehabilitation, 35(6), 829-839. https://doi.org/10.1177/0269215520978859

OBJECTIVE: To evaluate the feasibility of a multi-centre randomised controlled trial to compare the clinical and cost-effectiveness of early patient-directed rehabilitation versus standard rehabilitation following surgical repair of the rotator cuff... Read More about Rehabilitation following rotator cuff repair: A multi-centre pilot & feasibility randomised controlled trial (RaCeR).

Characterization of regional meniscal cell and chondrocyte phenotypes and chondrogenic differentiation with histological analysis in osteoarthritic donor-matched tissues (2020)
Journal Article
Wang, J., Roberts, S., Kuiper, J., Zhang, W., Garcia, J., Cui, Z., & Wright, K. (2020). Characterization of regional meniscal cell and chondrocyte phenotypes and chondrogenic differentiation with histological analysis in osteoarthritic donor-matched tissues. Scientific reports, 10, Article 21658. https://doi.org/10.1038/s41598-020-78757-6

Meniscus degeneration is closely related to the progression of knee osteoarthritis (OA). However, there is currently a lack of quantitative and objective metrics to assess OA meniscal cell phenotypes. In this study we investigated the phenotypic mark... Read More about Characterization of regional meniscal cell and chondrocyte phenotypes and chondrogenic differentiation with histological analysis in osteoarthritic donor-matched tissues.

Dementia Research Activity in Sri Lanka: A Review (2020)
Journal Article
Abhayasinghe, K., Dissanayake, L., Saunders, B., Campbell, P., & Sumathipala, A. (2020). Dementia Research Activity in Sri Lanka: A Review. Journal of Neurodegenerative Disorders, 3(1), 89-100. https://doi.org/10.36959/459/603

Background: As a result of the global rise in life expectancy, dementia has become a major global health concern; it is considered to be one of the most burdensome conditions of later life. Despite 66% of older adults with dementia living in Low-and-... Read More about Dementia Research Activity in Sri Lanka: A Review.

The complete evaluation of tube potential on clinical image quality when using direct digital detectors for pelvis and lumbar spine radiography: Re: 'An evaluation of the effect of tube potential on clinical image quality using direct digital detectors for pelvis and lumbar spine radiographs' by Peacock, Steward and Riley. (2020)
Journal Article
(2020). The complete evaluation of tube potential on clinical image quality when using direct digital detectors for pelvis and lumbar spine radiography: Re: 'An evaluation of the effect of tube potential on clinical image quality using direct digital detectors for pelvis and lumbar spine radiographs' by Peacock, Steward and Riley. Journal of Medical Radiation Sciences, https://doi.org/10.1002/jmrs.429

Correspondence, Re: ‘An evaluation of the effect of tube potential on clinical image quality using direct digital detectors for pelvis and lumbar spine radiographs’ by Peacock, Steward and Riley.

The LENT index predicts 30 day outcomes following hospitalization for heart failure (2020)
Journal Article
Mamas. (2020). The LENT index predicts 30 day outcomes following hospitalization for heart failure. ESC Heart Failure, https://doi.org/10.1002/ehf2.13109

AIMS: The LE index (Length of hospitalization plus number of Emergent visits =6 months) predicts 30 day all-cause readmission or death following hospitalization for heart failure (HF). We combined N-terminal pro-B type natriuretic peptide (NT-proBNP)... Read More about The LENT index predicts 30 day outcomes following hospitalization for heart failure.

Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register. (2020)
Journal Article
Iskandar, I., Warren, R., Lunt, M., Mason, K., Evans, I., McElhone, K., …Ashcroft, D. (2020). Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register. JAMA Dermatology, 157(1), 66-73. https://doi.org/10.1001/jamadermatol.2020.4202

Importance: Treatments for psoriasis may be less effective in everyday practice than in clinical trials. Emulating a target trial using data from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) can provide t... Read More about Randomized Trial Replication Using Observational Data for Comparative Effectiveness of Secukinumab and Ustekinumab in Psoriasis: A Study From the British Association of Dermatologists Biologics and Immunomodulators Register..

Periodization in Anterior Cruciate Ligament Rehabilitation: A Novel Framework (2020)
Journal Article
(2020). Periodization in Anterior Cruciate Ligament Rehabilitation: A Novel Framework. Medical Principles and Practice, 1 - 8. https://doi.org/10.1159/000511228

More than 250,000 anterior cruciate ligament (ACL) injuries occur each year in the USA, and approximately 65% of these injuries undergo reconstructive surgery. Appropriate rehabilitation after ACL reconstruction can yield predictably good outcomes, w... Read More about Periodization in Anterior Cruciate Ligament Rehabilitation: A Novel Framework.

Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. (2020)
Journal Article
Mamas. (2020). Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample. Resuscitation, 166 - 173. https://doi.org/10.1016/j.resuscitation.2020.10.005

AIMS: The aim of this study is to analyse the causes of cardiac arrests (CA) in the emergency departments (ED) in the United States and their clinical outcomes according to whether they had a primary or a secondary diagnosis of CA. METHODS: Data from... Read More about Cardiac arrest and related mortality in emergency departments in the United States: Analysis of the nationwide emergency department sample..

The prognostic value of Tei index in acute myocardial infarction: a systematic review (2020)
Journal Article
(2020). The prognostic value of Tei index in acute myocardial infarction: a systematic review. Echo Research and Practice, 49 - 58. https://doi.org/10.1530/ERP-20-0017

Background: Echocardiographic evaluation of left ventricular ejection fraction (LVEF) is used in the risk stratification of patients with an acute myocardial infarction (AMI). However, the prognostic value of the Tei index, an alternative measure of... Read More about The prognostic value of Tei index in acute myocardial infarction: a systematic review.