An interpretive phenomenological study of nursing insights into the formation of the therapeutic nurse patient relationship within acute psychiatric wards (2022)
Thesis
Fieldhouse, C. J. (2022). An interpretive phenomenological study of nursing insights into the formation of the therapeutic nurse patient relationship within acute psychiatric wards. (Thesis). Keele University

This study has concerned itself with the therapeutic nature of the relationship between psychiatric nurses and the inpatients of acute psychiatric wards. In particular it sought the insights that those nurses held in relation to their strategic endea... Read More about An interpretive phenomenological study of nursing insights into the formation of the therapeutic nurse patient relationship within acute psychiatric wards.

Assessing the impact of comorbidity measures on outcomes following acute coronary syndrome (2022)
Thesis
Zhang, F. (2022). Assessing the impact of comorbidity measures on outcomes following acute coronary syndrome. (Thesis). Keele University

Acute coronary syndromes (ACS) are a common acute presentation of cardiovascular disease (CVD) associated with significant morbidity, mortality and societal economic burden. With improvements in medical care and post- ACS survival rates, ACS patients... Read More about Assessing the impact of comorbidity measures on outcomes following acute coronary syndrome.

The impact of the COVID-19 pandemic and stringent social distancing measures on health-related quality of life and COVID-19 infection rates in patients with rheumatic disease: a longitudinal analysis through the pandemic (2022)
Journal Article
Cox, N., R Raizada, S., Barkham, N., Venkatachalam, S., Sheeran, T. P., Adizie, T., …Bateman, J. (2022). The impact of the COVID-19 pandemic and stringent social distancing measures on health-related quality of life and COVID-19 infection rates in patients with rheumatic disease: a longitudinal analysis through the pandemic. Rheumatology Advances in Practice, 7(1), Article rkad009. https://doi.org/10.1093/rap/rkad009

Objective The aim was to evaluate the impact of the coronavirus disease 2019 (COVID-19) pandemic and stringent social isolation measures on patients with rheumatic disease (RD) from the beginning of the pandemic (April 2020). Methods In this UK-based... Read More about The impact of the COVID-19 pandemic and stringent social distancing measures on health-related quality of life and COVID-19 infection rates in patients with rheumatic disease: a longitudinal analysis through the pandemic.

Risk-based stratified primary care for common musculoskeletal pain presentations: qualitative findings from the STarT MSK cluster randomised controlled trial. (2022)
Journal Article
Saunders, B., Chudyk, A., Protheroe, J., Cooper, V., Bartlam, B., Birkinshaw, H., …Hill, J. C. (2022). Risk-based stratified primary care for common musculoskeletal pain presentations: qualitative findings from the STarT MSK cluster randomised controlled trial. BMC Primary Care, 23, Article 326. https://doi.org/10.1186/s12875-022-01924-3

BACKGROUND: The STarT MSK cluster randomised controlled trial (RCT) investigated the clinical- and cost-effectiveness of risk-based stratified primary care versus usual care for patients with back, neck, shoulder, knee or multi-site pain. Trial quant... Read More about Risk-based stratified primary care for common musculoskeletal pain presentations: qualitative findings from the STarT MSK cluster randomised controlled trial..

Ethnic differences in 25-year risk of incident chronic kidney disease among people with type 2 diabetes in New Zealand (2022)
Journal Article
Orr-Walker, B., Yu, D., Wang, Z., Cai, Y., Osuagwu, U., Pickering, K., …Simmons, D. (2022). Ethnic differences in 25-year risk of incident chronic kidney disease among people with type 2 diabetes in New Zealand. BMJ Open Diabetes Research and Care, https://doi.org/10.1136/bmjdrc-2022-003077

INTRODUCTION: Insights into ethnic differences in the natural history of chronic kidney disease (CKD) among people with type 2 diabetes mellitus (T2DM) might inform clinical strategies to address disparities in hospitalization and mortality. Risks of... Read More about Ethnic differences in 25-year risk of incident chronic kidney disease among people with type 2 diabetes in New Zealand.

Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. (2022)
Journal Article
Mamas. (2022). Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. PloS one, e0276731 - ?. https://doi.org/10.1371/journal.pone.0276731

BACKGROUND: Asthma is a prevalent chronic respiratory condition and remains a common cause for hospitalization. However, contemporary data on asthma hospitalization rates, comorbidity burden, and in-hospital outcomes are lacking.

METHODS: Survey-... Read More about Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study..

Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors (2022)
Journal Article
Makos, A., Kuiper, J., Kehoe, O., & Amarasena, R. (2022). Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors. Inflammopharmacology, 77-87. https://doi.org/10.1007/s10787-022-01092-x

Psoriatic arthritis (PsA) is a chronic and painful inflammatory immune-mediated disease. It affects up to 40% of people with psoriasis and it is associated with several comorbidities such as obesity, diabetes, metabolic syndrome and hypertension. PsA... Read More about Psoriatic arthritis: review of potential biomarkers predicting response to TNF inhibitors.

Open‐labelled study to monitor the effect of an amino acid formula on symptom management in children with spinal muscular atrophy type I: The SMAAF pilot study (2022)
Journal Article
Bowerman, M., O'Connor, G., Edel, L., Raquq, S., Szmurlo, A., Simpson, Z., …Baranello, G. (2023). Open‐labelled study to monitor the effect of an amino acid formula on symptom management in children with spinal muscular atrophy type I: The SMAAF pilot study. Nutrition in Clinical Practice, 38(4), 871-880. https://doi.org/10.1002/ncp.10940

Background: An increasing number of families of spinal muscular atrophy (SMA) children are incorporating an amino acid-based enteral formula into their child’s feeding regimens. Other components of the amino acidbased formula include added carbohydra... Read More about Open‐labelled study to monitor the effect of an amino acid formula on symptom management in children with spinal muscular atrophy type I: The SMAAF pilot study.

A Critical Evaluation of Patient Pathways and Missed Opportunities in Treatment for Heart Failure. (2022)
Journal Article
Shing Kwok, C., Satchithananda, D., Ahmed, F. Z., Chue, C. D., Barker, D., Patwala, A., …Mallen, C. D. (2022). A Critical Evaluation of Patient Pathways and Missed Opportunities in Treatment for Heart Failure. Journal of Cardiovascular Development and Disease, 9(12. Special issue Heart Failure: Clinical Diagnostics and Treatment), https://doi.org/10.3390/jcdd9120455

BACKGROUND: Heart failure (HF) is a global problem responsible for significant morbidity and mortality. METHODS: This review describes the patient pathways and missed opportunities related to treatment for patients with HF. RESULTS: The contemporary... Read More about A Critical Evaluation of Patient Pathways and Missed Opportunities in Treatment for Heart Failure..

A systematic review of the global prevalence and incidence of shoulder pain (2022)
Journal Article
Lucas, J., van Doorn, P., Hegedus, E., Lewis, J., & Van Der Windt, D. (2022). A systematic review of the global prevalence and incidence of shoulder pain. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-022-05973-8

Background and objectives
Studies reporting on the population burden of people living with shoulder pain show wide heterogeneity in terms of case definition, study samples, and occurrence. This systematic review aims to summarize evidence pertaining... Read More about A systematic review of the global prevalence and incidence of shoulder pain.

Predictors of perceived risk in first-degree relatives of patients with rheumatoid arthritis. (2022)
Journal Article
Bunnewell, S., Wells, I., Zemedikun, D., Simons, G., Mallen, C. D., Raza, K., & Falahee, M. (2022). Predictors of perceived risk in first-degree relatives of patients with rheumatoid arthritis. RMD Open, https://doi.org/10.1136/rmdopen-2022-002606

OBJECTIVES: To define variables associated with perceived risk of developing rheumatoid arthritis (RA) in first-degree relatives (FDRs) of patients with RA. METHODS: Patients with RA and their FDRs were invited to complete cross-sectional surveys. FD... Read More about Predictors of perceived risk in first-degree relatives of patients with rheumatoid arthritis..

Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019 (2022)
Journal Article
Yu, D., Jordan, K. P., Wilkie, R., Bailey, J., Fitzpatrick, J., Ali, N., …Peat, G. (2022). Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019. Rheumatology Advances in Practice, 7(1), https://doi.org/10.1093/rap/rkac106

Objective
To determine whether socioeconomic inequalities in primary care consultation rates for two major, disabling musculoskeletal conditions in England narrowed or widened between 2004-2019.

Methods
We analysed data from Clinical Practice Re... Read More about Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019.

Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial (2022)
Journal Article
Roffe. (2022). Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial. BMC Emergency Medicine, https://doi.org/10.1186/s12873-021-00560-x

Background: Prehospital stroke trials will inevitably recruit patients with non-stroke conditions, so called stroke mimics. We undertook a pre-specified analysis to determine outcomes in patients with mimics in the second Rapid Intervention with Glyc... Read More about Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial.

Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes (2022)
Journal Article
Mamas. (2022). Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes. Scientific reports, https://doi.org/10.1038/s41598-022-04929-1

<jats:title>Abstract</jats:title><jats:p>Mitochondrial dysfunction is a feature of type I and type II diabetes, but there is a lack of consistency between reports and links to disease development. We aimed to investigate if mitochondrial structure–fu... Read More about Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes.

Management of Concomitant Inflammatory Bowel Disease or Uveitis in Patients With Psoriatic Arthritis: An Updated Review Informing the 2021 GRAPPA Treatment Recommendations (2022)
Journal Article
R. Jadon, D., Corp, N., Van Der Windt, D., C. Coates, L., R. Soriano, E., Kavanaugh, A., …Elaine Husni, M. (2023). Management of Concomitant Inflammatory Bowel Disease or Uveitis in Patients With Psoriatic Arthritis: An Updated Review Informing the 2021 GRAPPA Treatment Recommendations. The Journal of Rheumatology, 50(3), 438-450. https://doi.org/10.3899/jrheum.220317

Objective: Several advanced therapies have been licensed across the related conditions of psoriatic arthritis (PsA), Crohn disease (CD), ulcerative colitis (UC), and noninfectious uveitis. We sought to summarize results from randomized controlled tri... Read More about Management of Concomitant Inflammatory Bowel Disease or Uveitis in Patients With Psoriatic Arthritis: An Updated Review Informing the 2021 GRAPPA Treatment Recommendations.

Effectiveness of adding motivational interviewing or a stratified vocational advice intervention to usual case management on return to work for people with musculoskeletal disorders: the MI-NAV randomised controlled trial. (2022)
Journal Article
Aanesen, F., Grotle, M., Rysstad, T., Storheim, K., Tveter, A., Tingulstad, A., …Øiestad, B. (2022). Effectiveness of adding motivational interviewing or a stratified vocational advice intervention to usual case management on return to work for people with musculoskeletal disorders: the MI-NAV randomised controlled trial. Occupational and Environmental Medicine, 42-50. https://doi.org/10.1136/oemed-2022-108637

OBJECTIVES: To evaluate if adding motivational interviewing (MI) or a stratified vocational advice intervention (SVAI) to usual case management (UC), reduced sickness absence over 6 months for workers on sick leave due to musculoskeletal disorders. M... Read More about Effectiveness of adding motivational interviewing or a stratified vocational advice intervention to usual case management on return to work for people with musculoskeletal disorders: the MI-NAV randomised controlled trial..

The use of plain radiography in diagnosing osteoarthritis: A systematic review and time trend analysis (2022)
Journal Article
Henry-Blake, C., Marshall, M., Treadwell, K., Parmar, S., Higgs, J., Edwards, J. J., & Peat, G. (2022). The use of plain radiography in diagnosing osteoarthritis: A systematic review and time trend analysis. Musculoskeletal Care, 21(2), 462-477. https://doi.org/10.1002/msc.1718

Introduction
The National Institute for Health and Care Excellence (NICE) suggest there is no role for routine radiography in the diagnosis of osteoarthritis (OA). It is not known how consistent this recommendation is across international guidelines... Read More about The use of plain radiography in diagnosing osteoarthritis: A systematic review and time trend analysis.

Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis (2022)
Journal Article
Gilchrist, F., Aspey, M., Bowler, R., Brodlie, M., Desai, S., Harris, C., …Carroll, W. D. (2022). Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis. BMJ Paediatrics Open, e001722 - e001722. https://doi.org/10.1136/bmjpo-2022-001722

Background Protracted bacterial bronchitis (PBB) is an endobronchial infection and a the most common cause of chronic wet cough in young children. It is treated with antibiotics, which can only be targeted if the causative organism is known. As most... Read More about Protocol for CLASSIC PBB: comparison of lower airway sampling strategies in children with protracted bacterial bronchitis.

Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults (2022)
Journal Article
Narayanasamy, M., Bishop, S., Sahota, O., Paskins, Z., Gittoes, N., & Langley, T. (2022). Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults. Age and ageing, https://doi.org/10.1093/ageing/afac255

Background: Osteoporosis is common in older adults leading to fragility fractures at enormous individual and economic cost. Improving long-term adherence with bisphosphonate treatments reduces fracture risk, but adherence rates for first line oral bi... Read More about Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults.

Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. (2022)
Journal Article
Wright, F. L., Cheema, K., Goldacre, R., Hall, N., Herz, N., Islam, N., …Banerjee, A. (2023). Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries. European Heart Journal - Quality of Care and Clinical Outcomes, 9(4), 377-388. https://doi.org/10.1093/ehjqcco/qcac077

Background
Although morbidity and mortality from COVID-19 have been widely reported, the indirect effects of the pandemic beyond 2020 on other major diseases and health service activity have not been well described.

Methods and results
Analyses... Read More about Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries..