Advancing Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion-Mutated Non-small Cell Lung Cancer (NSCLC) Management Through Molecular Diagnostics and Targeted Therapies.

Giridharan, Selvaraj; Ansari, Jawaher; Hussain, Imran

doi:10.7759/cureus.82573

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Two-stage crystallisation of the MFI zeolite: kinetic control for efficient catalyst development (2025)
Journal Article
Pavlov, V. S., Bruter, D. V., Efimov, A. V., Popov, A. G., Ivanova, I. I., & Zholobenko, V. L. (2025). Two-stage crystallisation of the MFI zeolite: kinetic control for efficient catalyst development. Microporous and Mesoporous Materials, 392(15 June 2025), Article 113649. https://doi.org/10.1016/j.micromeso.2025.113649

A detailed investigation of the MFI zeolite crystallisation mechanism in an alkaline synthetic gel system has been carried out using XRD, SEM, nitrogen adsorption, ammonia TPD, elemental analysis, NMR and FTIR spectroscopy. During the first stage of... Read More about Two-stage crystallisation of the MFI zeolite: kinetic control for efficient catalyst development.

How can we improve care for perinatal anxiety (PNA) in primary care? Insights from a community engagement and involvement event (2025)
Presentation / Conference Contribution
Silverwood, V., Proctor, J., Fisher, T., Kingstone, T., Turner, K., & Chew-Graham, C. (2025, March). How can we improve care for perinatal anxiety (PNA) in primary care? Insights from a community engagement and involvement event. Presented at BJGP Research and Publishing conference, The Lowry Hotel, Manchester, England

Background Perinatal anxiety (PNA) is anxiety that occurs during pregnancy or in the twelve months postpartum. Experienced by approximately 21% of women worldwide, PNA can have a negative impact on mothers, children and their families.

Aim A commu... Read More about How can we improve care for perinatal anxiety (PNA) in primary care? Insights from a community engagement and involvement event.

The importance of diagnosis from the perspectives of young people with Long COVID, their parents, and healthcare professionals (2025)
Presentation / Conference Contribution
Faux-Nightingale, A., Saunders, B., Burton, C., Chew-Graham, C. A., Somayajula, G., Twohig, H., & Welsh, V. (2025, March). The importance of diagnosis from the perspectives of young people with Long COVID, their parents, and healthcare professionals. Presented at BJGP Research and Publishing conference, The Lowry Hotel, Manchester, England

Background Long COVID describes symptoms persisting after an acute COVID-19 infection.

Aim This study explores the meaning and importance of a Long COVID diagnosis from the perspectives of children and young people (CYP) with Long COVID, their par... Read More about The importance of diagnosis from the perspectives of young people with Long COVID, their parents, and healthcare professionals.

How, why, for whom and when do help-seeking interventions for anxiety and depression work among older adults? A realist review (2025)
Presentation / Conference Contribution
Fisher, T., Chew-Graham, C., Corp, N., Hider, S., Southam, J., Wong, G., & Kingstone, T. (2025, March). How, why, for whom and when do help-seeking interventions for anxiety and depression work among older adults? A realist review. Presented at BJGP Research and Publishing conference, The Lowry Hotel, Manchester, England

Background A quarter of older adults (aged ≥60 years) in the UK experience a mental health problem each year. Older adults may not seek help due to limited awareness of symptoms of mental ill-health; fear of losing independence; limited access to ser... Read More about How, why, for whom and when do help-seeking interventions for anxiety and depression work among older adults? A realist review.

Advancing Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion-Mutated Non-small Cell Lung Cancer (NSCLC) Management Through Molecular Diagnostics and Targeted Therapies. (2025)
Journal Article
Giridharan, S., Ansari, J., & Hussain, I. (in press). Advancing Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion-Mutated Non-small Cell Lung Cancer (NSCLC) Management Through Molecular Diagnostics and Targeted Therapies. Cureus, 17(4), Article e82573. https://doi.org/10.7759/cureus.82573

Non-small cell lung cancer (NSCLC) associated with epidermal growth factor receptor (EGFR) mutations has experienced notable therapeutic advancements; however, exon 20 insertion mutations continue to pose a significant challenge, demonstrating resist... Read More about Advancing Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion-Mutated Non-small Cell Lung Cancer (NSCLC) Management Through Molecular Diagnostics and Targeted Therapies..