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A mixed-methods approach exploring acceptability and feasibility of trials designed to test drugs targeting prevention of post-traumatic osteoarthritis after knee injury (2024)
Journal Article
Kalsoum, R., Minns Lowe, C. J., Gilbert, S., McCaskie, A. W., Snow, M., Wright, K., …Watt, F. E. (in press). A mixed-methods approach exploring acceptability and feasibility of trials designed to test drugs targeting prevention of post-traumatic osteoarthritis after knee injury. Bone & Joint Research, 13(9), 513-524. https://doi.org/10.1302/2046-3758.139.bjr-2024-0109

Aims
To explore key stakeholder views around feasibility and acceptability of trials seeking to prevent post-traumatic osteoarthritis (PTOA) following knee injury, and provide guidance for next steps in PTOA trial design.

Methods
Healthcare prof... Read More about A mixed-methods approach exploring acceptability and feasibility of trials designed to test drugs targeting prevention of post-traumatic osteoarthritis after knee injury.

The Intersection of Socioeconomic Differences and Sex in the Management and Outcomes of Acute Myocardial Infarction: A Nationwide Cohort Study (2024)
Journal Article
Weight, N., Moledina, S., Lawson, C. A., Van Spall, H. G. C., Wijeysundera, H. C., Rashid, M., …Mamas, M. A. (in press). The Intersection of Socioeconomic Differences and Sex in the Management and Outcomes of Acute Myocardial Infarction: A Nationwide Cohort Study. Angiology, https://doi.org/10.1177/00033197241273433

Patients with lower socioeconomic status (SES) have poorer outcomes following acute myocardial infarction (AMI) than patients with higher SES; however, how sex modifies socioeconomic differences is unclear. Using the United Kingdom (UK) Myocardial Is... Read More about The Intersection of Socioeconomic Differences and Sex in the Management and Outcomes of Acute Myocardial Infarction: A Nationwide Cohort Study.

Bifunctional Imine Reductase Cascades for the Synthesis of Saturated N-Heterocycles (2024)
Journal Article
Ramsden, J. I., Zucoloto da Costa, B., Heath, R. S., Marshall, J. R., Derrington, S. R., Mangas-Sanchez, J., …Turner, N. J. (2024). Bifunctional Imine Reductase Cascades for the Synthesis of Saturated N-Heterocycles. ACS catalysis, 14(19), 14703-14710. https://doi.org/10.1021/acscatal.4c03832

Saturated N-heterocycles constitute a vital scaffold for pharmaceutical chemistry but are challenging to access synthetically, particularly asymmetrically. Here, we demonstrate how imine reductases can achieve annulation through tandem inter- and int... Read More about Bifunctional Imine Reductase Cascades for the Synthesis of Saturated N-Heterocycles.

Rediscussion of eclipsing binaries. Paper XX. HO Tel checkout (2024)
Journal Article
Southqorth, J. (2024). Rediscussion of eclipsing binaries. Paper XX. HO Tel checkout. Observatory, 144(1302), https://doi.org/10.48550/arXiv.2408.12955

We present a detailed analysis of the detached eclipsing binary system HO Telescopii, which contains two A-type stars in a circular orbit of period 1.613 d. We use light curves from the Transiting Exoplanet Survey Satellite (TESS), which observed HO... Read More about Rediscussion of eclipsing binaries. Paper XX. HO Tel checkout.

Rediscussion of eclipsing binaries. Paper XIX. The long-period solar-type system V454 Aurigae (2024)
Journal Article
Southworth, J. (2024). Rediscussion of eclipsing binaries. Paper XIX. The long-period solar-type system V454 Aurigae. Observatory, 144(1301), https://doi.org/10.48550/arXiv.2404.19443

V454 Aur is an eclipsing binary system containing two solar- type stars on an orbit of relatively long period (P P = 2702 d) and large eccentricity (e e = 0381). Eclipses were detected using data from the Hipparcos satellite, and a high-quality doubl... Read More about Rediscussion of eclipsing binaries. Paper XIX. The long-period solar-type system V454 Aurigae.