Outputs (12)

Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT) (2019)
Presentation / Conference Contribution
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., Hall, A., Holden, M., Oppong, R., Stevenson, K., Menon, A., Roberts, P., Peat, G., Jinks, C., Foster, N., Mallen, C., & Roddy, E. (2019, November). Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT). Paper presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT).

Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain. (2019)
Journal Article
Lewis. (2019). Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain. Physical Therapy, 1551-1561. https://doi.org/10.1093/ptj/pzz107

BACKGROUND: Pregnancy-related low back pain and pelvic girdle pain (LBP/PGP) are common and negatively impact the lives of many pregnant women. Several patient-based outcome instruments measure treatment effect but there is no consensus about which m... Read More about Responsiveness and Minimal Important Change for Pain and Disability Outcome Measures in Pregnancy-Related Low Back and Pelvic Girdle Pain..

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care (2019)
Journal Article
Roddy, E., Clarkson, K., Bucknall, M., Mehta, R., Oppong, R., Avery, A., Hay, E., Heneghan, C., Hartshorne, L., Hooper, J., Hughes, G., Jowett, S., Lewis, M., Little, P., McCartney, K., Mahtani, K., Nunan, D., Santer, M., Williams, S., & Mallen, C. (2019). Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Annals of the Rheumatic Diseases, 79(2), https://doi.org/10.1136/annrheumdis-2019-216154

OBJECTIVES: To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care.

METHODS: This was a multicentre open-label randomised trial. Adults with a gout flare recruited from 100 general prac... Read More about Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs (2019)
Presentation / Conference Contribution
Lewis, M., Bromley, K., McCray, G., Sutton, C., & Lancaster, G. Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs. Presented at 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK

Introduction: The current CONSORT guidelines for reporting of pilot
trials do not recommend hypothesis testing of clinical outcomes on
the basis of a pilot trial being under-powered to detect such differences and this being the aim of the main tria... Read More about Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs.

Effect-based traffic light progression criteria for pilot studies (2019)
Presentation / Conference Contribution
McCray, G., Lewis, M., Bromley, K., & Lancaster, G. (2019, October). Effect-based traffic light progression criteria for pilot studies. Paper presented at 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK

Meeting abstract, from the 5th International Clinical Trials Methodology Conference (ICTMC 2019).

Predictors of Functional Outcome in Musculoskeletal Healthcare: An Umbrella Review (2019)
Journal Article
Burgess, R., Mansell, G., Bishop, A., Lewis, M., & Hill, J. (2019). Predictors of Functional Outcome in Musculoskeletal Healthcare: An Umbrella Review. European Journal of Pain, 24(1), 51-70. https://doi.org/10.1002/ejp.1483

BACKGROUND
Multiple cohort and systematic review studies exist, reporting independent predictive factors associated with outcome in musculoskeletal populations. These studies have found evidence for a number of 'generic' factors that have been shown... Read More about Predictors of Functional Outcome in Musculoskeletal Healthcare: An Umbrella Review.

Systematic Review of Decision Analytic Modelling in Economic Evaluations of Low Back Pain and Sciatica. (2019)
Journal Article
Hall, J. A., Konstantinou, K., Lewis, M., Oppong, R., Ogollah, R., & Jowett, S. (2019). Systematic Review of Decision Analytic Modelling in Economic Evaluations of Low Back Pain and Sciatica. Applied Health Economics and Health Policy, 17, 467-491. https://doi.org/10.1007/s40258-019-00471-w

BACKGROUND:
Low back pain (LBP) and sciatica place significant burden on individuals and healthcare systems, with societal costs alone likely to be in excess of £15 billion. Two recent systematic reviews for LBP and sciatica identified a shortage of... Read More about Systematic Review of Decision Analytic Modelling in Economic Evaluations of Low Back Pain and Sciatica..

Can patients with low health literacy be identified from routine primary care health records? A cross-sectional and prospective analysis. (2019)
Journal Article
Campbell, P., Lewis, M., Chen, Y., Lacey, R., Rowlands, G., & Protheroe, J. (2019). Can patients with low health literacy be identified from routine primary care health records? A cross-sectional and prospective analysis. BMC Family Practice, 101 -?. https://doi.org/10.1186/s12875-019-0994-8

BACKGROUND:
People with low health literacy (HL) are at increased risk of poor health outcomes, and receive less benefit from healthcare services. However, healthcare practitioners can effectively adapt healthcare information if they are aware of th... Read More about Can patients with low health literacy be identified from routine primary care health records? A cross-sectional and prospective analysis..

Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm (2019)
Journal Article
Konstantinou, K., Dunn, K., Windt, D., Ogollah, R., Jasani, V., & Foster, N. (2019). Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm. BMC Musculoskeletal Disorders, https://doi.org/10.1186/s12891-019-2686-x

Background
Sciatica is a painful condition managed by a stepped care approach for most patients. Currently, there are no decision-making tools to guide matching care pathways for patients with sciatica without evidence of serious pathology, early in... Read More about Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm.

Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis (2019)
Journal Article
Kigozi, J., Konstantinou, K., Ogollah, R., Dunn, K., Lewis, M., & Jowett, S. (2019). Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis. BMC Health Services Research, https://doi.org/10.1186/s12913-019-4257-0

Background
There is limited research on the economic burden of low back-related leg pain, including sciatica. The aim of this study was to describe healthcare resource utilisation and factors associated with cost and health outcomes in primary care... Read More about Factors associated with costs and health outcomes in patients with Back and leg pain in primary care: a prospective cohort analysis.