Outputs (45)

Investigating multisite pain as a predictor of self-reported falls and falls requiring health care use in an older population: A prospective cohort study. (2019)
Journal Article
Welsh, V., Mallen, C., Ogollah, R., Wilkie, R., & McBeth, J. (2019). Investigating multisite pain as a predictor of self-reported falls and falls requiring health care use in an older population: A prospective cohort study. PloS one, -. https://doi.org/10.1371/journal.pone.0226268

Older people are continuing to fall despite fall prevention guidelines targeting known falls' risk factors. Multisite pain is a potential novel falls' risk factor requiring further exploration. This study hypothesises that: (1) an increasing number o... Read More about Investigating multisite pain as a predictor of self-reported falls and falls requiring health care use in an older population: A prospective cohort study..

Naproxen or low-dose colchicine for gout flares in primary care? Response to: 'Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care' by Parperis et al. (2019)
Journal Article
Roddy, E., & Mallen, C. (2019). Naproxen or low-dose colchicine for gout flares in primary care? Response to: 'Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care' by Parperis et al. Annals of the Rheumatic Diseases, https://doi.org/10.1136/annrheumdis-2019-216671

Correspondence response.

Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study (2019)
Journal Article
Muller, S., Whittle, R., Hider, S. L., Belcher, J., Helliwell, T., Morton, C., Hughes, E., Lawton, S. A., & Mallen, C. D. (2020). Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study. Rheumatology, 59(8), 1906-1915. https://doi.org/10.1093/rheumatology/kez533

Objectives. To investigate potential subgroups of primary care diagnosed patients with polymyalgia rheumatica (PMR) based on self-reported pain and stiffness severity over time.

Methods. 652 people with an incident PMR diagnosis were recruited fro... Read More about Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study.

Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT) (2019)
Presentation / Conference Contribution
Paskins, Z., Bromley, K., Lewis, M., Hughes, G., Hughes, E., Cherrington, A., Hall, A., Holden, M., Oppong, R., Stevenson, K., Menon, A., Roberts, P., Peat, G., Jinks, C., Foster, N., Mallen, C., & Roddy, E. (2019, November). Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT). Paper presented at 2019 ACR/ARP Annual Meeting, Atlanta, GA, USA

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT).

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care (2019)
Journal Article
Roddy, E., Clarkson, K., Bucknall, M., Mehta, R., Oppong, R., Avery, A., Hay, E., Heneghan, C., Hartshorne, L., Hooper, J., Hughes, G., Jowett, S., Lewis, M., Little, P., McCartney, K., Mahtani, K., Nunan, D., Santer, M., Williams, S., & Mallen, C. (2019). Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care. Annals of the Rheumatic Diseases, 79(2), https://doi.org/10.1136/annrheumdis-2019-216154

OBJECTIVES: To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care.

METHODS: This was a multicentre open-label randomised trial. Adults with a gout flare recruited from 100 general prac... Read More about Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia (2019)
Journal Article
Jayaweera, K., M Craig, J., M S Zavos, H., Abeysinghe, N., De Alwis, S., Andras, A., Dissanayake, L., Dziedzic, K., Fernando, B., Glozier, N., Hewamalage, A., Ives, J., Jordan, K. P., Kodituwakku, G., Mallen, C., Rahman, O., Zafar, S., Saxena, A., Rijsdijk, F., Saffery, R., …Sumathipala, A. (2019). Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia. BMJ Open, 9(10), Article e029332. https://doi.org/10.1136/bmjopen-2019-029332

INTRODUCTION: Worldwide, 10%-20% of children and adolescents experience mental health conditions. However, most such disorders remain undiagnosed until adolescence or adulthood. Little is known about the factors that influence mental health in childr... Read More about Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia.

Prognostic value of comorbidity indices and lung diseases in early rheumatoid arthritis: a UK population-based study (2019)
Journal Article
Mallen. (2019). Prognostic value of comorbidity indices and lung diseases in early rheumatoid arthritis: a UK population-based study. Rheumatology, 1296-1305. https://doi.org/10.1093/rheumatology/kez409

We assessed comorbidity burden in people with RA at diagnosis and early disease (3 years) and its association with early mortality and joint destruction. The association between lung disease and mortality in RA is not well studied; we also explored t... Read More about Prognostic value of comorbidity indices and lung diseases in early rheumatoid arthritis: a UK population-based study.

The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis. (2019)
Journal Article
Chen, W. M., Subesinghe, S., Muller, S., Hider, S. L., Mallen, C. D., & Scott, I. C. (2019). The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism, 50(2), 252-260. https://doi.org/10.1016/j.semarthrit.2019.09.003

OBJECTIVE: To establish if gravidity and parity associate with the development of rheumatoid arthritis (RA), and to establish if this effect is influenced by the time elapsed since pregnancy/childbirth, the number of pregnancies/childbirths, and sero... Read More about The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis..

DIabetes Severity SCOre (DISSCO) improves hospitalisation and mortality prediction: model development and validation in 139,626 people with type 2 diabetes (2019)
Presentation / Conference Contribution
Zghebi, S., Mamas, M., Ashcroft, D. M., Salisbury, C., Mallen, C., Chew-Graham, C., Reeves, D., Van marwijk, H., Qureshi, N., Weng, S., Holt, T., Buchan, I., Peek, N., Rutter, M., & Kontopantelis, E. (2019, September). DIabetes Severity SCOre (DISSCO) improves hospitalisation and mortality prediction: model development and validation in 139,626 people with type 2 diabetes. Paper presented at 55th EASD Annual Meeting of the European Association for the Study of Diabetes, Barcelona, Spain

Haematological abnormalities in new onset rheumatoid arthritis and risk of common infections: a population-based study (2019)
Journal Article
Nikiphorou, E., de Lusignan, S., Mallen, C., Khavandi, K., Roberts, J., Buckley, C. D., Galloway, J., & Raza, K. (2020). Haematological abnormalities in new onset rheumatoid arthritis and risk of common infections: a population-based study. Rheumatology, 59(5), 997-1005. https://doi.org/10.1093/rheumatology/kez344

Objectives To describe the prevalence of haematological abnormalities in individuals with rheumatoid arthritis (RA) at the point of diagnosis in primary care, and the associations between haematological abnormalities, vaccinations and subsequent risk... Read More about Haematological abnormalities in new onset rheumatoid arthritis and risk of common infections: a population-based study.