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The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations (2021)
Journal Article
Mallen, C., Khunti, K., & Mughal, F. (2021). The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations. Journal of Family Medicine and Primary Care, 4345-4349. https://doi.org/10.4103/jfmpc.jfmpc_756_21

COVID-19 has changed health systems and services. In this commentary, we outline the impact COVID-19 has had on the delivery of primary health care, and on primary care teams, and describe the NHS response. We highlight the challenges of managing lon... Read More about The impact of COVID-19 on primary care: insights from the National Health Service (NHS) and future recommendations.

Misdiagnosis of aortic dissection: A systematic review of the literature (2021)
Journal Article
Mallen. (2021). Misdiagnosis of aortic dissection: A systematic review of the literature. American Journal of Emergency Medicine, https://doi.org/10.1016/j.ajem.2021.11.047

Background
Aortic dissection is a rare but potentially catastrophic condition. Misdiagnosis of aortic dissection is not uncommon as symptoms can overlap with other diagnoses.

Objective
We conducted a systematic review to better understand the fa... Read More about Misdiagnosis of aortic dissection: A systematic review of the literature.

An evaluation of the use of investigations in a nurse-led rapid access chest pain clinic (2021)
Journal Article
Mallen. (2021). An evaluation of the use of investigations in a nurse-led rapid access chest pain clinic. British Journal of Cardiac Nursing, 1 - 14. https://doi.org/10.12968/bjca.2021.0084

<jats:sec><jats:title>Background/Aims</jats:title><jats:p> Chest pain is a common symptom, but its presentation and cause varies widely, making diagnosis a challenge. This study describes the authors' experience of a nurse-led rapid access chest pain... Read More about An evaluation of the use of investigations in a nurse-led rapid access chest pain clinic.

Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients (2021)
Journal Article
Mallen, Wells, I., T Zemedikun, D., Simons, G., J Stack, R., D Mallen, C., Raza, K., & Falahee, M. (2022). Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients. Rheumatology, 61(8), https://doi.org/10.1093/rheumatology/keab890

OBJECTIVES: There is increasing interest in prediction and prevention of rheumatoid arthritis (RA). It is important to understand the views of those at risk to inform the development of effective approaches. First-degree relatives (FDRs) of RA patien... Read More about Predictors of interest in predictive testing for rheumatoid arthritis among first degree relatives of rheumatoid arthritis patients.

Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study (2021)
Journal Article
Paskins, Z., Sokhal, B. S., Hider, S. L., Mallen, C. D., & Muller, S. (2021). Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study. Rheumatology Advances in Practice, Article rkab094. https://doi.org/10.1093/rap/rkab094

OBJECTIVES: PMR is a common indication for long-term glucocorticoid treatment, leading to an increased risk of osteoporosis and fragility fractures. Guidelines recommend calcium and vitamin D for all patients, in addition to anti-resorptive agents fo... Read More about Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study.

Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data (2021)
Journal Article
Scott, I. C., Bailey, J., White, C. R., Mallen, C., & Muller, S. (2022). Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data. Rheumatology, 61(8), 3201–3211. https://doi.org/10.1093/rheumatology/keab870

OBJECTIVES: International data suggest inflammatory arthritis (IA) pain management frequently involves opioid prescribing, despite little evidence of efficacy, and potential harms. We evaluated analgesia prescribing in English National Health Service... Read More about Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data.

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference Contribution
Mason, K., Jordan, K., Achana, F., Bailey, J., Chen, Y., Frisher, M., Heron, N., Huntley, A., Mallen, C., Mamas, M., Marshall, M., Png, M., Tatton, S., White, S., & Edwards, J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Poster presented at 2021 SAPC North, Virtual

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference Contribution
Mason, K., Jordan, K. P., Achana, F., Bailey, J., Chen, Y., Frisher, M., Heron, N., Huntley, A., Mallen, C. D., Mamas, M. A., Marshall, M., Png, M., Tatton, S., White, S., & Edwards, J. J. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Paper presented at 2021 SAPC North, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM) (2021)
Presentation / Conference Contribution
Mallen, Mason, K., Frisher, Mamas, Jordan, Marshall, Heron, & White. (2021, November). Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM). Presented at SAPC North 2021, Virtual

Background: There is evidence that painful musculoskeletal conditions are associated with increased risk of cardiovascular disease, but less is known about whether this impacts on prognosis of cardiovascular disease. The aim was to determine whether... Read More about Musculoskeletal pain and its impact on prognosis following hospitalisation for acute coronary syndrome or cerebrovascular accident: a linked electronic health record cohort study (MSKCOM).

Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum (2021)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Taal, M. W., Aithal, G. P., Zhang, W., Doherty, M., Fox, C. P., Mallen, C. D., & Abhishek, A. (2022). Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum. Rheumatology, 61(7), 2783–2791. https://doi.org/10.1093/rheumatology/keab790

OBJECTIVE: To develop and validate a prognostic model for leflunomide discontinuation with abnormal blood-test results. METHODS: Data from CPRD Gold and Aurum were used for model development and external validation respectively. Participants prescrib... Read More about Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum.