Outputs (2)

Decline in Rate of Colonization of Oligodendrocyte Progenitor Cell (OPC)-Depleted Tissue by Adult OPCs with Age (2003)
Journal Article
Chari, D. M., Crang, A. J., & Blakemore, W. F. (2003). Decline in Rate of Colonization of Oligodendrocyte Progenitor Cell (OPC)-Depleted Tissue by Adult OPCs with Age. Journal of Neuropathology and Experimental Neurology, 62(9), 908-916. https://doi.org/10.1093/jnen/62.9.908

Rates of remyelination decline with age and this has been attributed to slower recruitment of oligodendrocyte progenitor cells (OPCs) into areas of demyelination and slower differentiation of OPCs into remyelinating oligodendrocytes. When considering... Read More about Decline in Rate of Colonization of Oligodendrocyte Progenitor Cell (OPC)-Depleted Tissue by Adult OPCs with Age.

Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue (2003)
Journal Article
Chari, D., Huang, W., & Blakemore, W. (2003). Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue. Journal of Neuroscience Research, 73(6), 787-793. https://doi.org/10.1002/jnr.10700

We have attempted to extend a previously described rat model of focal oligodendrocyte progenitor cell (OPC) depletion, using 40 Gy X-irradiation (Chari and Blakemore [2002] Glia 37:307–313), to the adult mouse spinal cord, to examine the ability of O... Read More about Dysfunctional oligodendrocyte progenitor cell (OPC) populations may inhibit repopulation of OPC depleted tissue.