Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs
(2019)
Presentation / Conference Contribution
Lewis, M., Bromley, K., McCray, G., Sutton, C., & Lancaster, G. Determining sample size for progression criteria using hypothesis testing in pragmatic pilot RCTs. Presented at 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK
Introduction: The current CONSORT guidelines for reporting of pilot
trials do not recommend hypothesis testing of clinical outcomes on
the basis of a pilot trial being under-powered to detect such differences and this being the aim of the main tria...
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