Skip to main content

Research Repository

Advanced Search

Outputs (9)

Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum (2024)
Journal Article
Scott, I. C., Daud, N., Bailey, J., Twohig, H., Hider, S. L., Mallen, C. D., Jordan, K. P., & Muller, S. (2024). Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum. BMC Medicine, 22(1), 575. https://doi.org/10.1186/s12916-024-03774-5

Background: Gabapentinoids are increasingly prescribed in inflammatory arthritis (IA), despite no trial evidence for efficacy at managing pain in this population. Observational studies in non-IA populations suggest gabapentinoids are associated with... Read More about Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum.

Association of air pollution from a landfill site with primary care consultation (2024)
Preprint / Working Paper
Jordan, K. P., Muller, S., Usman, M., Bailey, J., Burton, C., Lawton, S. A., Mallen, C. D., Mason, K. J., Wathall, S., & van der Windt, D. A. Association of air pollution from a landfill site with primary care consultation

Background Waste landfill sites are associated with gaseous emissions and this air pollution can cause unpleasant smells (“malodour”). This causes concerns about its impact on the health of the local population. This study assessed change in general... Read More about Association of air pollution from a landfill site with primary care consultation.

Management of musculoskeletal pain in children and young people with mental health or neurodivergent comorbidity (CLIMB Study) (2024)
Presentation / Conference
Jenkinson, D., Bailey, J., Mughal, F., Dunn, K., & Mason, K. (2024, July). Management of musculoskeletal pain in children and young people with mental health or neurodivergent comorbidity (CLIMB Study). Presented at SAPC ASM 2024, Bristol

SNOMED Clinical terminology and Clinical Practice Record Datalink (CPRD) AURUM dataset code lists from the CLIMB Study:

The aim of the CLIMB study is to investigate whether children and young people (aged 8-18 years) with musculoskeletal pain are... Read More about Management of musculoskeletal pain in children and young people with mental health or neurodivergent comorbidity (CLIMB Study).

AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM (2024)
Presentation / Conference Contribution
Scott, I., Daud, N., Bailey, J., Twohig, H., Hider, S., Mallen, C., Jordan, K., & Muller, S. AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM. Presented at EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria, Vienna

Background: Recent observational studies suggest gabapentinoids associate with an increased risk of fractures. The potential for confounding inherent to non-randomised studies of interventions, however, alongside th... Read More about AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM.

Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study (2024)
Presentation / Conference Contribution
Fisher, T., Archer, C., Bailey, J., Evans, J., Kessler, D. S., Kingstone, T., Petersen, I., Proctor, J., Shivji, N., Spruce, A., Silverwood, V., Smith, H., Turner, K., Wu, P., Yu, D., & Chew-Graham, C. (2024, March). Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study. Presented at BJGP Research & Publishing Conference, RCGP Headquarters in London, England, UK

Perinatal anxiety (PNA) occurs throughout the antenatal period or up to 1 year after childbirth, with a prevalence of 21%. To investigate if primary care records could be used to identify women at 'higher risk' of PNA. Mixed-methods approach using qu... Read More about Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study.

P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study (2024)
Presentation / Conference Contribution
Mason, K. J., Jordan, K. P., Bailey, J., Jöud, A., Jowett, S., Protheroe, J., Mughal, F., Snell, K. I. E., Thomas, M., & Dunn, K. M. (2024, April). P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims
Musculoskeletal pain in childhood increases the risk of such pain in adulthood but there is an absence of management guidance for this group, not helped by a lack of evidence on the extent and nature of pain in children. The aim was... Read More about P051 Trends in consultations for musculoskeletal pain in children and young people presenting to United Kingdom primary care: an electronic health record study.

Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study. (2024)
Journal Article
Ghosal, S., Heron, N., Mason, K., Bailey, J., & Jordan, K. (2024). Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study. British Journal of General Practice (BJGP), BJGP.2023.0684. https://doi.org/10.3399/bjgp.2023.0684

Orlistat is recommended as an adjunct to diet and exercise for weight loss in type 2 diabetes mellitus (T2DM). The aims were to explore (i) associations between patient characteristics and orlistat prescribing and to determine (ii) associations of or... Read More about Weight Management with Orlistat in Type 2 Diabetes - An Electronic Healthcare Records Study..

Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study (2024)
Journal Article
Muller, S., Bailey, J., Bajpai, R., Helliwell, T., Harrisson, S. A., Whittle, R., Mallen, C. D., & Ashworth, J. (2024). Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study. PAIN, https://doi.org/10.1097/j.pain.0000000000003239

Growing evidence from pharmacovigilance data and postmortem toxicology reports highlights the misuse potential of gabapentinoids. This study aimed to investigate the risk of serious adverse outcomes (drug misuse, overdose, major trauma), and their ri... Read More about Risk of adverse outcomes during gabapentinoid therapy and factors associated with increased risk in UK primary care using the clinical practice research datalink: a cohort study.

The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation (2024)
Journal Article
Stevenson, K., Hadley‐Barrows, T., Evans, N., Campbell, L., Southam, J., Chudyk, A., Ellington, D., Jeeves, B., Jenson, C., Kleberg, S., Birkinshaw, H., Mair, F., Dziedzic, K., Peat, G., Jordan, K. P., Yu, D., Bailey, J., Braybooke, A., Mallen, C. D., & Hill, J. C. (2024). The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation. Musculoskeletal Care, 22(1), Article e1876. https://doi.org/10.1002/msc.1876

Introduction
Globally, back pain is the leading cause of years of disability. In the United Kingdom, over 20 million people live with musculoskeletal (MSK) pain, with low back pain being one of the most common causes. National strategies promote sel... Read More about The SelfSTarT intervention for low back pain patients presenting to first contact physiotherapists: A mixed methods service evaluation.