Outputs (3)

Long non-coding RNA HAND2-AS1 inhibits invasion and metastasis in endometrioid endometrial carcinoma through inactivating neuromedin U (2017)
Journal Article
Yang, X., Wang, C. C., Lee, W. Y. W., Trovik, J., Chung, T. K. H., & Kwong, J. (2018). Long non-coding RNA HAND2-AS1 inhibits invasion and metastasis in endometrioid endometrial carcinoma through inactivating neuromedin U. Cancer Letters, 413, 23-34. https://doi.org/10.1016/j.canlet.2017.10.028

Endometrioid endometrial carcinoma (EEC) is one of the common causes of cancer-related mortality in women. Mounting evidences suggest that long noncoding RNAs (lncRNAs) function in multiple cancers. In this study, we discovered that HAND2-AS1, a lncR... Read More about Long non-coding RNA HAND2-AS1 inhibits invasion and metastasis in endometrioid endometrial carcinoma through inactivating neuromedin U.

A prodrug of green tea polyphenol (–)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancer (2017)
Journal Article
Wang, J., Man, G. C. W., Chan, T. H., Kwong, J., & Wang, C. C. (2018). A prodrug of green tea polyphenol (–)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancer. Cancer Letters, 412, 10-20. https://doi.org/10.1016/j.canlet.2017.09.054

Anti-angiogenesis effect of a prodrug of green tea polyphenol (–)-epigallocatechin-3-gallate (Pro-EGCG) in malignant tumors is not well studied. Here, we investigated how the treatment with Pro-EGCG inhibited tumor angiogenesis in endometrial cancer.... Read More about A prodrug of green tea polyphenol (–)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancer.

A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFa-TGFa-EGFR. (2017)
Journal Article
Kwong. (2017). A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFa-TGFa-EGFR. Oncogene, 3576 - 3587. https://doi.org/10.1038/onc.2016.509

Peritoneum is the most common site for ovarian cancer metastasis. Here we investigate how cancer epigenetics regulates reciprocal tumor-stromal interactions in peritoneal metastasis of ovarian cancer. Firstly, we find that omental stromal fibroblasts... Read More about A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFa-TGFa-EGFR..