Outputs (3)

Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system. (2018)
Journal Article
Kwong, J. (2018). Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system. Journal of Ovarian Research, 36 - ?. https://doi.org/10.1186/s13048-018-0403-2

BACKGROUND: Ovarian cancer stem cells (OCSCs) contribute to the poor prognosis of ovarian cancer. Involvement of the androgen receptor (AR) in the malignant behaviors of other tumors has been reported. However, whether AR associates with Nanog (a ste... Read More about Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system..

MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target (2018)
Journal Article
Zhang, T., Zhou, J., Man, G. C. W., Leung, K. T., Liang, B., Xiao, B., Ma, X., Huang, S., Huang, H., Hegde, V. L., Zhong, Y., Li, Y., Kong, G. W. S., Yiu, A. K. W., Kwong, J., Ng, P. C., Lessey, B. A., Nagarkatti, P. S., Nagarkatti, M., & Wang, C. C. (2018). MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target. European Journal of Immunology, 48(6), 1059-1073. https://doi.org/10.1002/eji.201747417

Endometriosis affects women of reproductive age via unclear immunological mechanism(s). Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid cells with potent immunosuppressive and angiogenic properties. Here, we found MDSCs... Read More about MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target.

Clinicopathological and prognostic significance of blood microvessel density in endometrial cancer: a meta-analysis and subgroup analysis (2018)
Journal Article
Wang, J. Z., Xiong, Y. J., Man, G. C. W., Chen, X. Y., Kwong, J., & Wang, C. C. (2018). Clinicopathological and prognostic significance of blood microvessel density in endometrial cancer: a meta-analysis and subgroup analysis. Archives of Gynecology and Obstetrics, 297(3), 731-740. https://doi.org/10.1007/s00404-018-4648-1

Objective
The study aimed to systematically review the association between angiogenesis and clinicopathological characteristics and its prognostic value in patients with endometrial cancer.

Methods
Eligible studies were searched in PubMed, Embas... Read More about Clinicopathological and prognostic significance of blood microvessel density in endometrial cancer: a meta-analysis and subgroup analysis.