Outputs (169)

Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019 (2022)
Journal Article
Wei, S., Miranda, J. J., Mamas, M. A., Zühlke, L. J., Kontopantelis, E., Thabane, L., & Van Spall, H. G. C. (2023). Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019. European Heart Journal - Quality of Care and Clinical Outcomes, 9(7), 662-672. https://doi.org/10.1093/ehjqcco/qcac088

Background Heart failure (HF) is a global epidemic. Objective To assess global sex differences in HF epidemiology across country income levels. Methods and results Using Global Burden of Disease (GBD) data from 204 countries and territories 1990–2019... Read More about Sex differences in the etiology and burden of heart failure across country income level: analysis of 204 countries and territories 1990–2019.

Social Deprivation and Post-TAVR Outcomes in Ontario, Canada: A Population-Based Study. (2022)
Journal Article
Patel, R. V., Ravindran, M., Qiu, F., Manoragavan, R., Sud, M., Tam, D. Y., Madan, M., Marcus, G., Mamas, M. A., Elbaz-Greener, G., & Wijeysundera, H. C. (2023). Social Deprivation and Post-TAVR Outcomes in Ontario, Canada: A Population-Based Study. Journal of the American Heart Association, 12(1), Article e028144. https://doi.org/10.1161/JAHA.122.028144

Background Transcatheter aortic valve replacement (TAVR)/intervention has become the standard of care for treatment of severe aortic stenosis across the spectrum of risk. There are socioeconomic disparities in access to TAVR. The impact of these disp... Read More about Social Deprivation and Post-TAVR Outcomes in Ontario, Canada: A Population-Based Study..

Phenotyping for percutaneous coronary intervention and long-term recurrent weighted outcomes (2022)
Journal Article
Mamas. (2022). Phenotyping for percutaneous coronary intervention and long-term recurrent weighted outcomes. International Journal of Cardiology, 374, 12 - 19. https://doi.org/10.1016/j.ijcard.2022.12.035

Introduction Percutaneous coronary interventions (PCI) are often performed in multimorbid patients with heterogeneous characteristics and variable clinical outcomes. We aimed to identify distinct clinical phenotypes utilizing machine learning and exp... Read More about Phenotyping for percutaneous coronary intervention and long-term recurrent weighted outcomes.

Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry (2022)
Journal Article
Mamas. (2022). Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry. European Heart Journal, 5020-5032. https://doi.org/10.1093/eurheartj/ehac511

Background and Aims Postinfarction ventricular septal defect (PIVSD) is a mechanical complication of myocardial infarction (MI) with a poor prognosis. Surgical repair is the mainstay of treatment, although percutaneous closure is increasingly underta... Read More about Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry.

Sex differences in clinical profile and outcome after percutaneous coronary intervention for chronic total occlusion. (2022)
Journal Article
Mamas, & Rashid. (2022). Sex differences in clinical profile and outcome after percutaneous coronary intervention for chronic total occlusion. Cardiovascular Revascularization Medicine, 49, 34-41. https://doi.org/10.1016/j.carrev.2022.12.005

BACKGROUND: There are limited data around sex differences in the risk profile, treatments and outcomes of percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) lesions in contemporary interventional practice. We investigated the i... Read More about Sex differences in clinical profile and outcome after percutaneous coronary intervention for chronic total occlusion..

Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. (2022)
Journal Article
Mamas. (2022). Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study. PloS one, e0276731 - ?. https://doi.org/10.1371/journal.pone.0276731

BACKGROUND: Asthma is a prevalent chronic respiratory condition and remains a common cause for hospitalization. However, contemporary data on asthma hospitalization rates, comorbidity burden, and in-hospital outcomes are lacking.

METHODS: Survey-... Read More about Temporal trends of hospitalizations, comorbidity burden and in-hospital outcomes in patients admitted with asthma in the United States: Population-based study..

Aortic valve treatment: from the first aortic valve replacement to the last decade of revolution (2022)
Journal Article
Paradies, V., & Mamas, M. A. (2022). Aortic valve treatment: from the first aortic valve replacement to the last decade of revolution. Heart, heartjnl-2022-321933. https://doi.org/10.1136/heartjnl-2022-321933

The first aortic valve replacement (AVR) from a human patient performed in 1962 marked the beginning of an evidence-based journey of open-heart surgery for aortic valve stenosis (AVS). Surgical aortic valve replacement (SAVR) has long been the standa... Read More about Aortic valve treatment: from the first aortic valve replacement to the last decade of revolution.

Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes (2022)
Journal Article
Mamas. (2022). Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes. Scientific reports, https://doi.org/10.1038/s41598-022-04929-1

<jats:title>Abstract</jats:title><jats:p>Mitochondrial dysfunction is a feature of type I and type II diabetes, but there is a lack of consistency between reports and links to disease development. We aimed to investigate if mitochondrial structure–fu... Read More about Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes.

Comparison of Transfemoral versus Transsubclavian/Transaxillary access for transcatheter aortic valve replacement: A systematic review and meta-analysis (2022)
Journal Article
Mamas. (2022). Comparison of Transfemoral versus Transsubclavian/Transaxillary access for transcatheter aortic valve replacement: A systematic review and meta-analysis. https://doi.org/10.1016/j.ijcha.2022.101156

Femoral access is the gold standard for transcatheter aortic valve replacement (TAVR). Safe alternative access, that represents about 15 % of TAVR cases, remains important for patients without adequate transfemoral access. We aimed to perform a syste... Read More about Comparison of Transfemoral versus Transsubclavian/Transaxillary access for transcatheter aortic valve replacement: A systematic review and meta-analysis.

Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis. (2022)
Journal Article
Mamas, & Rashid. (2022). Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis. https://doi.org/10.1016/j.ijcha.2022.101135

Background: Individuals who present with STEMI without the standard cardiovascular risk factors (SMuRFs) of diabetes, hypercholesterolemia, hypertension, and smoking, coined SMuRF-less are not uncommon. Little is known about their outcomes as a cohor... Read More about Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis..