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Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank (2023)
Journal Article
Runhaar, J., A Holden, M., Hattle, M., Quicke, J., Healey, E. L., van der Windt, D., …Menek, M. Y. (2023). Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank. RMD Open, 9(3), Article e003220. https://doi.org/10.1136/rmdopen-2023-003220

Objectives: To evaluate mediating factors for the effect of therapeutic exercise on pain and physical function in people with knee/hip osteoarthritis (OA). Methods: For Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (... Read More about Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank.

Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment? (2023)
Journal Article
Nicolson, P. J. A., & Holden, M. A. (2023). Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment?. Current Treatment Options in Rheumatology, 9(3), 120-131. https://doi.org/10.1007/s40674-023-00208-w

Purpose of review: Patient-centred care for people with osteoarthritis requires shared decision making. Understanding and considering patients’ preferences for osteoarthritis treatments is central to this. In this narrative review, we present an over... Read More about Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment?.

Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis (2023)
Journal Article
Holden, M. A., Hattle, M., Runhaar, J., Riley, R. D., Healey, E. L., Quicke, J., …Exercise Collaborative, O. T. B. (2023). Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis. The Lancet Rheumatology, 5(7), e386-e400. https://doi.org/10.1016/S2665-9913%2823%2900122-4

Background Many international clinical guidelines recommend therapeutic exercise as a core treatment for knee and hip osteoarthritis. We aimed to identify individual patient-level moderators of the effect of therapeutic exercise for reducing pain an... Read More about Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis.

Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). (2023)
Journal Article
Foster, N. E., Nicholls, E., Holden, M. A., Healey, E. L., Hay, E. M., & trial team, T. B. (2023). Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). Archives of Rehabilitation Research and Clinical Translation, 5(2), Article 100266. https://doi.org/10.1016/j.arrct.2023.100266

To investigate whether knee osteoarthritis (OA) related pain and function can be improved by offering enhanced physical therapist-led exercise interventions. Three-arm prospectively designed pragmatic randomized controlled trial. General practices an... Read More about Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial)..

Evaluating Osteoarthritis Management Programs: outcome domain recommendations from the OARSI Joint Effort Initiative. (2023)
Journal Article
Allen, K., Huffman, K., Cleveland, R., van der Esch, M., Abbott, J., Abbott, A., …Hinman, R. (2023). Evaluating Osteoarthritis Management Programs: outcome domain recommendations from the OARSI Joint Effort Initiative. Osteoarthritis and Cartilage, 31(7), 954-965. https://doi.org/10.1016/j.joca.2023.02.078

Objective To develop sets of core and optional recommended domains for describing and evaluating Osteoarthritis Management Programs (OAMPs), with a focus on hip and knee Osteoarthritis (OA). Design We conducted a 3-round modified Delphi survey i... Read More about Evaluating Osteoarthritis Management Programs: outcome domain recommendations from the OARSI Joint Effort Initiative..

What should a toolkit to aid the delivery of therapeutic exercise for hip and knee osteoarthritis look like? Qualitative analysis of an international survey of 318 researchers, clinicians, and consumers by the OARSI Rehabilitation Discussion Group (2023)
Journal Article
Holden, M. A., Lawford, B. J., Master, H., Larsen, J. B., Bartholdy, C., Corrigan, P., …White, D. K. (2023). What should a toolkit to aid the delivery of therapeutic exercise for hip and knee osteoarthritis look like? Qualitative analysis of an international survey of 318 researchers, clinicians, and consumers by the OARSI Rehabilitation Discussion Group. Musculoskeletal Care, 21(2), 545-555. https://doi.org/10.1002/msc.1732

BACKGROUND: We aimed to identify important components of, and practical resources relevant for inclusion in, a toolkit to aid exercise delivery for people with hip/knee osteoarthritis. METHOD: An online international multi-disciplinary survey was con... Read More about What should a toolkit to aid the delivery of therapeutic exercise for hip and knee osteoarthritis look like? Qualitative analysis of an international survey of 318 researchers, clinicians, and consumers by the OARSI Rehabilitation Discussion Group.

Conceptualising adherence to exercise for musculoskeletal pain: A concept mapping study (2022)
Journal Article
Bailey, D., Bishop, A., Foster, N. E., & Holden, M. A. (2023). Conceptualising adherence to exercise for musculoskeletal pain: A concept mapping study. Physiotherapy Research International, 28(2), https://doi.org/10.1002/pri.1989

AbstractBackgroundThe concept of adherence to exercise for musculoskeletal (MSK) pain is poorly defined and inadequately measured. This study aimed to, (1) conceptualise adherence to exercise therapy for MSK pain, and (2) identify statements most rep... Read More about Conceptualising adherence to exercise for musculoskeletal pain: A concept mapping study.

Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group (2022)
Journal Article
Holden, M., Metcalf, B., Lawford, B., Hinman, R., Boyd, M., Button, K., …Bennell, K. (2023). Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group. Osteoarthritis and Cartilage, 31(3), 386-396. https://doi.org/10.1016/j.joca.2022.10.009

Objective To develop evidence-informed recommendations to support the delivery of best practice therapeutic exercise for people with knee and/or hip osteoarthritis (OA). Design A multi-stage, evidence-informed, international multi-disciplinary c... Read More about Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group.

Osteoarthritis year in review 2022: rehabilitation (2022)
Journal Article
Holden, M., Nicolson, P., Thomas, M., Corp, N., Hinman, R., & Bennell, K. (2023). Osteoarthritis year in review 2022: rehabilitation. Osteoarthritis and Cartilage, 31(2), 177-186. https://doi.org/10.1016/j.joca.2022.10.004

This year in review presents key highlights from research relating to osteoarthritis (OA) rehabilitation published from the 1st April 2021 to the 18th March 2022. To identify studies for inclusion in the review, an electronic database search was carr... Read More about Osteoarthritis year in review 2022: rehabilitation.

Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial. (2022)
Journal Article
Holden. (2022). Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial. BMC Musculoskeletal Disorders, 733 - ?. https://doi.org/10.1186/s12891-022-05685-z

BACKGROUND: Obesity is associated with knee osteoarthritis (OA). Weight loss, alongside exercise, is a recommended treatment for individuals with knee OA and overweight/obesity. However, many patients cannot access weight loss specialists such as die... Read More about Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial..